Structural Classification of Proteins
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Family: PAPS sulfotransferase

Pfam 00685
similar to the nucleotide/nucleoside kinases but transfer sulphate group

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: P-loop containing nucleoside triphosphate hydrolases [52539]
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily: P-loop containing nucleoside triphosphate hydrolases [52540]
    division into families based on beta-sheet topologies
    link to SUPERFAMILY database - Superfamily
  5. Family: PAPS sulfotransferase [52575]
    Pfam 00685
    similar to the nucleotide/nucleoside kinases but transfer sulphate group

Protein Domains:

  1. Estrogen sulfotransferase (STE, sult1e1) [52576]
    1. Mouse (Mus musculus) [TaxId: 10090] [52577] (3)
      1. 1aqu picpic
        complexed with a3p, est
        1. chain a [31942] picpiclink
        2. chain b [31943] picpiclink
      2. 1aqy picpic
        complexed with a3p
        1. chain a [31944] picpiclink
        2. chain b [31945] picpiclink
      3. 1bo6 picpic
        complexed with a3p, vo4
        1. chain a [31946] picpiclink
        2. chain b [31947] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [75198] (2)
      1. 1g3m picpic
        complexed with a3p, edo, pcq
        1. chain a [83268] picpiclink
        2. chain b [83269] picpiclink
      2. 1hy3 picpic
        complexed with pps; mutant
        1. chain a [71090] picpiclink
        2. chain b [71091] picpiclink
  2. Hydroxysteroid sulfotransferase sult2a1 [52578]
    1. Human (Homo sapiens) [TaxId: 9606] [52579] (3)
      1. 1j99 picpic
        complexed with and, hgi, iod
        1. chain a [71618] picpiclink
      2. 1efh picpic
        complexed with a3p
        1. chain a [31948] picpiclink
        2. chain b [31949] picpiclink
      3. 1ov4 picpic
        complexed with ae2, so4; mutant
        1. chain a [93581] picpiclink
  3. Aryl sulfotransferase sult1a [102346]
    1. Human (Homo sapiens) [TaxId: 9606] [102347] (3)
      1. 1ls6 picpic
        complexed with a3p, npo
        1. chain a [91115] picpiclink
      2. 2d06 picpic
        automatically matched to d1ls6a_
        complexed with a3p, est
        1. region a:8-295 [131061] picpiclink
      3. 2d06 picpic
        automatically matched to d1ls6a_
        complexed with a3p, est
        1. region b:8-295 [131062] picpiclink
  4. Aryl sulfotransferase sult1a3 [52580]
    1. Human (Homo sapiens) [TaxId: 9606] [52581] (3)
      1. 2a3r picpic
        automatically matched to d1cjma_
        complexed with a3p, ldp
        1. region a:9-293 [126094] picpiclink
      2. 2a3r picpic
        automatically matched to d1cjma_
        complexed with a3p, ldp
        1. region b:9-293 [126095] picpiclink
      3. 1cjm picpic
        1. chain a [31950] picpiclink
  5. Pregnenolone sulfotransferase sult2b1a [102348]
    1. Human (Homo sapiens) [TaxId: 9606] [102349] (1)
      cytosolic enzyme
      1. 1q1q picpic
        complexed with a3p, na, nhe
        1. chain a [95599] picpiclink
  6. Cholesterol sulfotransferase sult2b1b [102350]
    1. Human (Homo sapiens) [TaxId: 9606] [102351] (3)
      cytosolic enzyme
      1. 1q20 picpic
        complexed with a3p, na, plo
        1. chain a [95616] picpiclink
      2. 1q1z picpic
        complexed with a3p, na
        1. chain a [95615] picpiclink
      3. 1q22 picpic
        complexed with a3p, and, na
        1. chain a [95617] picpiclink
  7. Putative steroid sulfotransferase rarO47 [102352]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [102353] (2)
      1. 1q44 picpic
        complexed with mla
        1. chain a [95779] picpiclink
      2. 2q3m picpic
        automatically matched to d1q44a_
        complexed with mla
        1. region a:6-325 [139795] picpiclink
  8. Heparan sulfate N-deacetylase/N-sulfotransferase domain [52582]
    1. Human (Homo sapiens) [TaxId: 9606] [52583] (1)
      1. 1nst picpic
        complexed with a3p
        1. chain a [31951] picpiclink
  9. Heparan sulfate 3-O-sulfotransferase [102354]
    1. Mouse (Mus musculus) [TaxId: 10090] [102355] (1)
      SQ O35310 48-311
      1. 1vkj picpic
        complexed with a3p, so4; mutant
        1. chain a [108666] picpiclink
        2. chain b [108667] picpiclink
        3. chain c [108668] picpiclink
  10. Retinol dehydratase [64015]
    1. Fall armyworm (Spodoptera frugiperda) [TaxId: 7108] [64016] (2)
      1. 1fmj picpic
        complexed with a3p, ca, hg, rtl
        1. chain a [59879] picpiclink
        2. chain b [59880] picpiclink
      2. 1fml picpic
        complexed with a3p, ca, rtl
        1. chain a [59881] picpiclink
        2. chain b [59882] picpiclink
  11. Stf0 sulfotransferase [110530]
    1. Mycobacterium smegmatis [TaxId: 1772] [110531] (1)
      SQ P84151
      1. 1tex picpic
        complexed with tre
        1. chain a [106818] picpiclink
        2. chain b [106819] picpiclink
        3. chain c [106820] picpiclink
        4. chain d [106821] picpiclink
  12. Heparan sulfate glucosamine 3-O-sulfotransferase 3 [110532]
    1. Human (Homo sapiens) [TaxId: 9606] [110533] (2)
      SQ Q9Y663 139-406 # isoform 3A1; 100% sequence identity to isoform 3B1 domain (SQ Q9Y662 133-390)
      1. 1t8t picpic
        complexed with a3p, cit
        1. chain a [106685] picpiclink
        2. chain b [106686] picpiclink
      2. 1t8u picpic
        complexed with a3p, ids, na, sgn, so4, uap
        1. chain a [106687] picpiclink
        2. chain b [106688] picpiclink
  13. Thyroid hormone sulfotransferase Sult1b1 [117530]
    1. Human (Homo sapiens) [TaxId: 9606] [117531] (1)
      SQ O43704
      1. 1xv1 picpic
        complexed with a3p
        1. chain a [116074] picpiclink
        2. chain b [116075] picpiclink
  14. Sulfotransferase Sult1c2 [159556]
    1. Human (Homo sapiens) [TaxId: 9606] [159557] (2)
      SQ O00338 12-296
      1. 3bfx picpic
        complexed with a3p; mutant
        1. region a:12-296 [155239] picpiclink
      2. 3bfx picpic
        automatically matched to 3BFX A:12-296
        complexed with a3p; mutant
        1. region b:12-296 [155240] picpiclink

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
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