Superfamily: HAD-like

usually contains an insertion (sub)domain after strand 1
uperfamily

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: HAD-like [56783]
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456
4. Superfamily: HAD-like [56784]
   usually contains an insertion (sub)domain after strand 1
   uperfamily

Families:

1. Probable phosphatase YrbI [69467] (1)
   the insertion subdomain is a beta-hairpin involved into tetramerisation
2. HAD-related [56785] (3)
   the insertion subdomain is a 4-helical bundle
3. beta-Phosphoglucomutase-like [75173] (9)
   the insertion subdomain is a 4-helical bundle
4. YihX-like [56789] (3)
   the insertion subdomain is a 4-helical bundle
5. Phosphonoacetaldehyde hydrolase-like [56792] (2)
   the insertion subdomain is a 4-helical bundle
6. Phosphoserine phosphatase [64511] (2)
   the insertion subdomain is a 4-helical bundle
7. 5'(3')-deoxyribonucleotidase (dNT-2) [82382] (1)
   the insertion subdomain is a 4-helical bundle; dephosphorylates dUMP and dTMP
8. Homoserine kinase ThrH [102304] (1)
   the insertion subdomain is a rudiment 4-helical bundle
9. Class B acid phosphatase, AphA [102307] (2)
   the insertion subdomain is a helical hairpin
10. Hypothetical protein MW1667 (SA1546) [102310] (1)
    the insertion subdomain is multi-helical
11. phosphatase domain of polynucleotide kinase [82385] (2)
    no insertion subdomains
12. Predicted hydrolases Cof [82388] (13)
    contains an alpha+beta subdomain inserted into a new site after strand 3
13. NagD-like [102317] (6)
    duplication: consists of two segment-swapped domains of this fold; this results in the insertion of a circularly permuted domain after strand 3, analogously to the Cof family
14. Meta-cation ATPase, catalytic domain P [81656] (2)
    interrupted by a large insertion, domain N
15. Trehalose-phosphatase [110506] (1)
    Pfam 02358; contains an insert alpha+beta subdomain; similar overall fold to the Cof family
16. NLI interacting factor-like phosphatase [110509] (1)
    Pfam 03031; NIF; the insertion subdomain is a 3-stranded beta-sheet;
17. Magnesium-dependent phosphatase-1, Mdp1 [117509] (1)
    the insertion subdomain is a 3-stranded beta-sheet different from the NIF family
18. Hypothetical protein VC0232 [117512] (1)
    contains a deletion in the common fold; segment-swapped tetramer
19. Histidinol phosphatase-like [142177] (3)
    no insertion subdomains
20. MtnX-like [142180] (1)
    Pfam 06888; the insertion subdomain is a rudiment 4-helical bundle
21. Pyrimidine 5'-nucleotidase (UMPH-1) [142183] (2)
    Pfam 05822; the insertion subdomain is a rudiment 4-helical bundle
22. Enolase-phosphatase E1 [142186] (2)
    the insertion subdomain is a 4-helical bundle
23. 5' nucleotidase-like [142191] (1)
    Pfam 05761; the insertion domain cosists of 3-helical bundle and a pseudo beta-barrel; contains extra C-terminal long alpha hairpin subdomain (scop_cf 46556)
24. AF1437-like [159537] (1)
    the insertion subdomain is a rudiment 4-helical bundle; extra alpha-hairpin insertion after strand 3
25. BT0820-like [159540] (1)
    PfamB 073209; deletion in the common fold; segment-swapped dimer

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk