Structural Classification of Proteins
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Superfamily: Cobalamin (vitamin B12)-binding domain

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Flavodoxin-like [52171]
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. Superfamily: Cobalamin (vitamin B12)-binding domain [52242]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Cobalamin (vitamin B12)-binding domain [52243] (6)
    1. Methionine synthase, C-terminal domain [52244]
      1. Escherichia coli [TaxId: 562] [52245] (4)
        1. 3bul picpicxrefxref
          automatically matched to d1bmta2
          complexed with b12; mutant
          1. region a:741-896 [155621] picpiclink
        2. 1bmt picpicxref
          complexed with cob
          1. region a:741-896 [31235] picpiclink
          2. region b:741-896 [31236] picpiclink
        3. 1k7y picpicxrefxref
          complexed with b12, so4; mutant
          1. region a:741-900 [68273] picpiclink
        4. 1k98 picpicxrefxref
          complexed with b12, so4; mutant
          1. region a:741-900 [68339] picpiclink
    2. Glutamate mutase, small subunit [52246]
      1. Clostridium tetanomorphum [TaxId: 1553] [52247] (3)
        1. 1fmf picpic
          mutant
          1. chain a [65036] picpiclink
        2. 1id8 picpic
          complexed with dbi, fop; mutant
          1. chain a [62295] picpiclink
        3. 1be1 picpic
          mutant
          1. chain a [31237] picpiclink
      2. Clostridium cochlearium [TaxId: 1494] [52248] (4)
        1. 1ccw picpicxref
          complexed with cnc, tar; mutant
          1. chain a [31238] picpiclink
          2. chain c [31239] picpiclink
        2. 1i9c picpicxref
          complexed with 3md, 5ad, b12, glu; mutant
          1. chain a [71136] picpiclink
          2. chain c [71138] picpiclink
        3. 1cb7 picpicxref
          complexed with cob, tar; mutant
          1. chain a [31240] picpiclink
          2. chain c [31241] picpiclink
        4. 1b1a picpic
          mutant
          1. chain a [31242] picpiclink
    3. Methylmalonyl-CoA mutase alpha subunit, C-terminal domain [88717]
      active subunit; binds B12
      1. Propionibacterium freudenreichii, subsp. shermanii [TaxId: 1744] [88718] (8)
        1. 7req picpicxrefxrefxref
          complexed with 2cp, b12, gol; mutant
          1. region a:561-728 [31243] picpiclink
          2. region c:561-728 [31245] picpiclink
        2. 1req picpicxrefxrefxref
          complexed with b12, dca, gol; mutant
          1. region a:561-728 [31247] picpiclink
          2. region c:561-728 [31249] picpiclink
        3. 6req picpicxrefxrefxref
          complexed with 3cp, b12, gol; mutant
          1. region a:561-728 [31251] picpiclink
          2. region c:561-728 [31253] picpiclink
        4. 4req picpicxrefxrefxref
          complexed with 5ad, b12, gol, mca, sca; mutant
          1. region a:561-728 [31255] picpiclink
          2. region c:561-728 [31257] picpiclink
        5. 5req picpicxrefxrefxref
          complexed with b12, gol, mcd, scd; mutant
          1. region a:561-728 [31259] picpiclink
          2. region c:561-728 [31261] picpiclink
        6. 1e1c picpicxrefxrefxref
          complexed with b12, dca; mutant
          1. region a:561-728 [31263] picpiclink
          2. region c:561-728 [31265] picpiclink
        7. 2req picpicxrefxrefxref
          complexed with b12, coa; mutant
          1. region a:561-728 [31267] picpiclink
          2. region c:561-728 [31269] picpiclink
        8. 3req picpicxrefxrefxref
          complexed with aco; mutant
          1. region a:561-728 [31271] picpiclink
    4. Methylmalonyl-CoA mutase beta subunit, C-terminal domain [88719]
      inactive subunit
      1. Propionibacterium freudenreichii, subsp. shermanii [TaxId: 1744] [88720] (8)
        1. 7req picpicxrefxrefxref
          complexed with 2cp, b12, gol; mutant
          1. region b:476-638 [31244] picpiclink
          2. region d:476-638 [31246] picpiclink
        2. 1req picpicxrefxrefxref
          complexed with b12, dca, gol; mutant
          1. region b:476-638 [31248] picpiclink
          2. region d:476-638 [31250] picpiclink
        3. 6req picpicxrefxrefxref
          complexed with 3cp, b12, gol; mutant
          1. region b:476-638 [31252] picpiclink
          2. region d:476-638 [31254] picpiclink
        4. 4req picpicxrefxrefxref
          complexed with 5ad, b12, gol, mca, sca; mutant
          1. region b:476-638 [31256] picpiclink
          2. region d:476-638 [31258] picpiclink
        5. 5req picpicxrefxrefxref
          complexed with b12, gol, mcd, scd; mutant
          1. region b:476-638 [31260] picpiclink
          2. region d:476-638 [31262] picpiclink
        6. 1e1c picpicxrefxrefxref
          complexed with b12, dca; mutant
          1. region b:476-638 [31264] picpiclink
          2. region d:476-638 [31266] picpiclink
        7. 2req picpicxrefxrefxref
          complexed with b12, coa; mutant
          1. region b:476-637 [31268] picpiclink
          2. region d:476-637 [31270] picpiclink
        8. 3req picpicxrefxrefxref
          complexed with aco; mutant
          1. region b:476-637 [31272] picpiclink
    5. D-lysine 5,6-aminomutase beta subunit KamE, C-terminal domain [117477]
      most similar to the glutamate mutase subunit
      1. Clostridium sticklandii [TaxId: 1511] [117478] (1)
        SQ Q9ZFE5
        1. 1xrs picpicxrefxref
          complexed with 5ad, b12, plp
          1. region b:102-261 [115884] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk