Structural Classification of Proteins
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Family: Homocysteine S-methyltransferase

Pfam 02574

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: TIM beta/alpha-barrel [51350]
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily: Homocysteine S-methyltransferase [82282]
    link to SUPERFAMILY database - Superfamily
  5. Family: Homocysteine S-methyltransferase [82283]
    Pfam 02574

Protein Domains:

  1. Betaine-homocysteine S-methyltransferase [82284]
    1. Human (Homo sapiens) [TaxId: 9606] [82285] (2)
      1. 1lt7 picpic
        complexed with cit, sm; mutant
        1. chain a [78184] picpiclink
        2. chain b [78185] picpiclink
      2. 1lt8 picpic
        complexed with cbh, cit, zn; mutant
        1. chain a [78186] picpiclink
        2. chain b [78187] picpiclink
    2. Rat (Rattus norvegicus) [TaxId: 10116] [102107] (1)
      1. 1umy picpic
        complexed with bme, zn
        1. chain a [99635] picpiclink
        2. chain b [99636] picpiclink
        3. chain c [99637] picpiclink
        4. chain d [99638] picpiclink
  2. Cobalamin-dependent methionine synthase MetH, N-terminal domain [102108]
    5-methyltetrahydrofolate homocysteine S-methyltransferase
    1. Thermotoga maritima [TaxId: 2336] [102109] (10)
      1. 3bof picpicxrefxref
        automatically matched to d1q7ma2
        complexed with hcs, k, yt3, zn
        1. region a:1-300 [155446] picpiclink
      2. 3bof picpicxrefxref
        automatically matched to d1q7ma2
        complexed with hcs, k, yt3, zn
        1. region b:1-300 [155448] picpiclink
      3. 1q7z picpicxref
        complexed with cd
        1. region a:1-300 [96091] picpiclink
        2. region b:1-300 [96093] picpiclink
      4. 1q8a picpicxref
        complexed with cd, hcs
        1. region a:1-300 [96198] picpiclink
        2. region b:1-300 [96200] picpiclink
      5. 3bol picpicxrefxref
        automatically matched to d1q7ma2
        complexed with hcs, k, yt3, zn
        1. region a:1-300 [155454] picpiclink
      6. 3bol picpicxrefxref
        automatically matched to d1q7ma2
        complexed with hcs, k, yt3, zn
        1. region b:1-300 [155456] picpiclink
      7. 1q8j picpicxref
        complexed with c2f, cd, hcs
        1. region a:1-300 [96211] picpiclink
        2. region b:1-300 [96213] picpiclink
      8. 1q7m picpicxref
        1. region a:1-300 [96047] picpiclink
        2. region b:1-300 [96049] picpiclink
      9. 1q85 picpicxref
        complexed with cd
        1. region a:1-300 [96159] picpiclink
        2. region b:1-300 [96161] picpiclink
      10. 1q7q picpicxref
        1. region a:1-300 [96051] picpiclink
        2. region b:1-300 [96053] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk