Structural Classification of Proteins
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Family: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain

the subunits are clearly related but only one (alpha) is active

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: TIM beta/alpha-barrel [51350]
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily: Cobalamin (vitamin B12)-dependent enzymes [51703]
    link to SUPERFAMILY database - Superfamily
  5. Family: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain [51704]
    the subunits are clearly related but only one (alpha) is active

Protein Domains:

  1. Methylmalonyl-CoA mutase alpha subunit, domain 1 [88709]
    1. Propionibacterium freudenreichii, subsp. shermanii [TaxId: 1744] [88710] (8)
      1. 7req picpicxrefxrefxref
        complexed with 2cp, b12, gol; mutant
        1. region a:4-560 [29616] picpiclink
        2. region c:4-560 [29618] picpiclink
      2. 1req picpicxrefxrefxref
        complexed with b12, dca, gol; mutant
        1. region a:2-560 [29620] picpiclink
        2. region c:2-560 [29622] picpiclink
      3. 6req picpicxrefxrefxref
        complexed with 3cp, b12, gol; mutant
        1. region a:2-560 [29624] picpiclink
        2. region c:2-560 [29626] picpiclink
      4. 4req picpicxrefxrefxref
        complexed with 5ad, b12, gol, mca, sca; mutant
        1. region a:3-560 [29628] picpiclink
        2. region c:3-560 [29630] picpiclink
      5. 5req picpicxrefxrefxref
        complexed with b12, gol, mcd, scd; mutant
        1. region a:4-560 [29632] picpiclink
        2. region c:4-560 [29634] picpiclink
      6. 1e1c picpicxrefxrefxref
        complexed with b12, dca; mutant
        1. region a:2-560 [29636] picpiclink
        2. region c:2-560 [29638] picpiclink
      7. 2req picpicxrefxrefxref
        complexed with b12, coa; mutant
        1. region a:4-560 [29640] picpiclink
        2. region c:4-560 [29642] picpiclink
      8. 3req picpicxrefxrefxref
        complexed with aco; mutant
        1. region a:4-560 [29644] picpiclink
  2. Methylmalonyl-CoA mutase beta subunit, domain 1 [88711]
    the subunits are clearly related but only one (alpha) is active
    1. Propionibacterium freudenreichii, subsp. shermanii [TaxId: 1744] [88712] (8)
      1. 7req picpicxrefxrefxref
        complexed with 2cp, b12, gol; mutant
        1. region b:16-475 [29617] picpiclink
        2. region d:16-475 [29619] picpiclink
      2. 1req picpicxrefxrefxref
        complexed with b12, dca, gol; mutant
        1. region b:20-475 [29621] picpiclink
        2. region d:17-475 [29623] picpiclink
      3. 6req picpicxrefxrefxref
        complexed with 3cp, b12, gol; mutant
        1. region b:20-475 [29625] picpiclink
        2. region d:20-475 [29627] picpiclink
      4. 4req picpicxrefxrefxref
        complexed with 5ad, b12, gol, mca, sca; mutant
        1. region b:20-475 [29629] picpiclink
        2. region d:20-475 [29631] picpiclink
      5. 5req picpicxrefxrefxref
        complexed with b12, gol, mcd, scd; mutant
        1. region b:20-475 [29633] picpiclink
        2. region d:20-475 [29635] picpiclink
      6. 1e1c picpicxrefxrefxref
        complexed with b12, dca; mutant
        1. region b:20-475 [29637] picpiclink
        2. region d:20-475 [29639] picpiclink
      7. 2req picpicxrefxrefxref
        complexed with b12, coa; mutant
        1. region b:17-475 [29641] picpiclink
        2. region d:17-475 [29643] picpiclink
      8. 3req picpicxrefxrefxref
        complexed with aco; mutant
        1. region b:16-475 [29645] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk