Structural Classification of Proteins
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Protein: Insulin receptor substrate 1, IRS-1 from Human (Homo sapiens) [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: PH domain-like barrel [50728]
    barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix
  4. Superfamily: PH domain-like [50729]
    link to SUPERFAMILY database - Superfamily
  5. Family: Phosphotyrosine-binding domain (PTB) [50755]
    Pfam 00640
  6. Protein: Insulin receptor substrate 1, IRS-1 [50758]
    duplication: contains two domains of this fold
  7. Species: Human (Homo sapiens) [TaxId: 9606] [50759]

PDB Entry Domains:

  1. 1qqg picpic
    1. region a:12-114 [26987] picpiclink
    2. region a:159-262 [26988] picpiclink
    3. region b:11-114 [26989] picpiclink
    4. region b:159-264 [26990] picpiclink
  2. 1irs picpic
    second domain complexed with a IL-4 receptor phosphopeptide
    1. chain a [26991] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk