Structural Classification of Proteins
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Family: Viral cysteine protease of trypsin fold

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Trypsin-like serine proteases [50493]
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. Superfamily: Trypsin-like serine proteases [50494]
    link to SUPERFAMILY database - Superfamily
  5. Family: Viral cysteine protease of trypsin fold [50603]

Protein Domains:

  1. 3C cysteine protease (picornain 3C) [50604]
    1. Human rhinovirus 2 [TaxId: 12130] [50605] (1) picpic
    2. Human hepatitis A virus [TaxId: 208726] [50606] (7) picpic
    3. Human poliovirus 1 Mahoney [TaxId: 12081] [74978] (3) picpic
    4. Foot-and-mouth disease virus FMDV [TaxId: 12110] [159189] (4) picpic
      SQ P49303 1657-1755! SQ P49303 1657-1857
  2. 2A cysteine proteinase [50607]
    1. Human rhinovirus 2 [TaxId: 12130] [50608] (1) picpic
  3. Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979]
    contains an extra alpha-helical domain
    1. Transmissible gastroenteritis virus [TaxId: 11149] [74980] (4) picpic
    2. Human coronavirus 229E [TaxId: 11137] [89348] (1) picpic
    3. SARS coronavirus [TaxId: 227859] [89349] (26) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk