Structural Classification of Proteins
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Superfamily: TIMP-like

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: OB-fold [50198]
    barrel, closed or partly opened n=5, S=10 or S=8; greek-key
  4. Superfamily: TIMP-like [50242]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Tissue inhibitor of metalloproteinases, TIMP [50243] (3)
    contains an irregular alpha+beta subdomain in the C-terminal extension
    1. TIMP-1 [50244]
      1. Human (Homo sapiens) [TaxId: 9606] [50245] (6)
        1. 2j0t picpicxrefxrefxref
          automatically matched to d1d2ba_
          complexed with ca, zn
          1. region d:1-124 [137920] picpiclink
        2. 2j0t picpicxrefxrefxref
          automatically matched to d1d2ba_
          complexed with ca, zn
          1. region e:1-124 [137921] picpiclink
        3. 2j0t picpicxrefxrefxref
          automatically matched to d1d2ba_
          complexed with ca, zn
          1. region f:1-124 [137922] picpiclink
        4. 1uea picpicxref
          complexed with ca, zn; mutant
          1. chain b [25232] picpiclink
          2. chain d [25233] picpiclink
        5. 1oo9 picpicxref
          1. chain b [87191] picpiclink
        6. 1d2b picpic
          1. chain a [25234] picpiclink
    2. TIMP-2 [50246]
      1. Human (Homo sapiens) [TaxId: 9606] [50247] (3)
        1. 1br9 picpic
          1. chain a [25235] picpiclink
        2. 1gxd picpicxrefxrefxrefxref
          complexed with proMMP-2
          complexed with ca, so4, zn; mutant
          1. chain c [70703] picpiclink
          2. chain d [70704] picpiclink
        3. 2tmp picpic
          mutant
          1. chain a [25236] picpiclink
      2. Cow (Bos taurus) [TaxId: 9913] [50248] (3)
        1. 2e2d picpicxref
          automatically matched to d1bqqt_
          complexed with ca, zn
          1. region c:1001-1180 [131980] picpiclink
        2. 1bqq picpicxref
          complexed with k, zn
          1. chain t [25237] picpiclink
        3. 1buv picpicxref
          complexed with ca, zn
          1. chain t [25238] picpiclink
  2. Netrin-like domain (NTR/C345C module) [89320] (2)
    Pfam 01759
    1. Procollagen c-proteinase enhancer protein PCOLCE [89321]
      1. Human (Homo sapiens) [TaxId: 9606] [89322] (1)
        1. 1uap picpic
          1. chain a [88385] picpiclink
    2. Complement C5 domain [117188]
      1. Human (Homo sapiens) [TaxId: 9606] [117189] (1)
        SQ P01031 1530-1676 # structure of the C5a anaphylotoxin domain (679-751) is also known (scop_sp 47689)
        1. 1xwe picpic
          mutant
          1. chain a [116125] picpiclink
  3. The laminin-binding domain of agrin [63767] (1)
    1. The laminin-binding domain of agrin [63768]
      1. Chicken (Gallus gallus) [TaxId: 9031] [63769] (3)
        SQ Q90685 # ! Fragment
        1. 1jb3 picpic
          1. chain a [62833] picpiclink
        2. 1pxu picpic
          1. chain a [104383] picpiclink
        3. 1jc7 picpic
          complexed with cl
          1. chain a [62873] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk