Structural Classification of Proteins
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Family: Superantigen toxins, N-terminal domain

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: OB-fold [50198]
    barrel, closed or partly opened n=5, S=10 or S=8; greek-key
  4. Superfamily: Bacterial enterotoxins [50203]
    link to SUPERFAMILY database - Superfamily
  5. Family: Superantigen toxins, N-terminal domain [50219]

Protein Domains:

  1. Staphylococcal enterotoxin A, SEA [50220]
    1. Staphylococcus aureus [TaxId: 1280] [50221] (6)
      1. 1esf picpicxref
        complexed with cd
        1. region a:1-120 [25146] picpiclink
        2. region b:1-120 [25147] picpiclink
      2. 1i4g picpicxref
        complexed with so4, zn; mutant
        1. region a:10-120 [25148] picpiclink
        2. region b:8-120 [25149] picpiclink
      3. 1i4h picpicxref
        complexed with zn; mutant
        1. region a:10-120 [25152] picpiclink
        2. region b:8-120 [25153] picpiclink
      4. 1sxt picpicxref
        complexed with zn
        1. region a:10-120 [25150] picpiclink
        2. region b:10-120 [25151] picpiclink
      5. 1lo5 picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-120 [78120] picpiclink
      6. 1dyq picpicxref
        mutant vaccine
        1. region a:6-120 [59140] picpiclink
  2. Staphylococcal enterotoxin C2, SEC2 [50222]
    1. Staphylococcus aureus [TaxId: 1280] [50223] (8)
      1. 1uns picpicxref
        complexed with zn
        1. region a:1-120 [99682] picpiclink
      2. 1i4p picpicxref
        complexed with zn
        1. region a:1-120 [61723] picpiclink
      3. 1i4r picpicxref
        complexed with zn
        1. region a:1-120 [61727] picpiclink
      4. 1ste picpicxref
        complexed with zn
        1. region a:1-120 [25154] picpiclink
      5. 1cqv picpicxref
        complexed with zn
        1. region a:1-120 [25155] picpiclink
      6. 1i4q picpicxref
        complexed with zn
        1. region a:1-120 [61725] picpiclink
      7. 1i4x picpicxref
        complexed with zn
        1. region a:1-120 [61736] picpiclink
      8. 1se2 picpicxref
        1. region a:1-120 [25156] picpiclink
  3. Toxic shock syndrome toxin-1 (TSST-1) [50224]
    1. Staphylococcus aureus [TaxId: 1280] [50225] (13)
      1. 2tss picpicxref
        1. region a:1-93 [25161] picpiclink
        2. region b:1-93 [25162] picpiclink
        3. region c:1-93 [25163] picpiclink
      2. 3tss picpicxref
        mutant
        1. region a:5-93 [25160] picpiclink
      3. 1aw7 picpicxref
        mutant
        1. region a:1-93 [25164] picpiclink
        2. region b:201-293 [25165] picpiclink
        3. region c:401-493 [25166] picpiclink
        4. region d:601-693 [25167] picpiclink
      4. 1ts3 picpicxref
        mutant
        1. region a:1-93 [25168] picpiclink
        2. region b:201-293 [25169] picpiclink
        3. region c:401-493 [25170] picpiclink
      5. 2qil picpicxref
        1. region a:1-93 [25157] picpiclink
        2. region b:1-93 [25158] picpiclink
        3. region c:1-93 [25159] picpiclink
      6. 1ts2 picpicxref
        mutant
        1. region a:1-93 [25174] picpiclink
        2. region b:201-293 [25175] picpiclink
        3. region c:401-493 [25176] picpiclink
      7. 1qil picpicxref
        mutant
        1. region a:1-93 [25171] picpiclink
        2. region b:1-93 [25172] picpiclink
        3. region c:1-93 [25173] picpiclink
      8. 1ts5 picpicxref
        mutant
        1. region a:1-93 [25179] picpiclink
        2. region b:201-293 [25180] picpiclink
      9. 2ij0 picpicxrefxrefxrefxref
        automatically matched to d1aw7a1
        1. region a:4-93 [137445] picpiclink
      10. 2ij0 picpicxrefxrefxrefxref
        automatically matched to d1aw7a1
        1. region b:4-93 [137447] picpiclink
      11. 5tss picpicxref
        1. region a:1-93 [25177] picpiclink
        2. region b:1-93 [25178] picpiclink
      12. 1ts4 picpicxref
        mutant
        1. region a:1-93 [25182] picpiclink
        2. region b:201-293 [25183] picpiclink
      13. 4tss picpicxref
        complexed with zn
        1. region a:1-93 [25181] picpiclink
  4. Staphylococcal enterotoxin B, SEB [50226]
    1. Staphylococcus aureus [TaxId: 1280] [50227] (12)
      1. 3seb picpicxref
        1. region a:1-121 [25184] picpiclink
      2. 1d5m picpicxrefxrefxrefxrefxref
        complexed with ace, nag
        1. region c:2-121 [25185] picpiclink
      3. 1d5z picpicxrefxrefxrefxrefxref
        complexed with ace, oda
        1. region c:2-121 [25186] picpiclink
      4. 1goz picpicxref
        mutant
        1. region a:1001-1121 [65435] picpiclink
        2. region b:2001-2121 [65437] picpiclink
      5. 1se4 picpicxref
        complexed with lat
        1. region a:1-121 [25187] picpiclink
      6. 1d6e picpicxrefxrefxrefxrefxref
        complexed with ace
        1. region c:2-121 [25188] picpiclink
      7. 1klg picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-121 [72718] picpiclink
      8. 1sbb picpicxrefxrefxref
        mutant
        1. region b:1-121 [25190] picpiclink
        2. region d:1-121 [25191] picpiclink
      9. 2seb picpicxrefxrefxrefxrefxref
        complexed with nag
        1. region d:2-121 [25192] picpiclink
      10. 1se3 picpicxref
        complexed with gal, glc, sia
        1. region a:1-121 [25189] picpiclink
      11. 1d5x picpicxrefxrefxrefxrefxref
        complexed with ace, haq
        1. region c:2-121 [25193] picpiclink
      12. 1seb picpicxrefxrefxrefxrefxref
        1. region d:2-121 [25194] picpiclink
        2. region h:2-121 [25195] picpiclink
  5. Staphylococcal enterotoxin C3, SEC3 [50228]
    1. Staphylococcus aureus [TaxId: 1280] [50229] (11)
      SQ P23313
      1. 1klu picpicxrefxrefxrefxrefxref
        1. region d:1-121 [72728] picpiclink
      2. 1pyw picpicxrefxrefxrefxrefxref
        complexed with ace; mutant
        1. region d:1-121 [95381] picpiclink
      3. 2ipk picpicxrefxrefxrefxrefxref
        automatically matched to d1jwmd1
        complexed with 4dp, ace; mutant
        1. region d:1-121 [137581] picpiclink
      4. 1ck1 picpicxref
        complexed with zn
        1. region a:1-121 [70067] picpiclink
      5. 1sjh picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-121 [105652] picpiclink
      6. 1jwu picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-121 [84252] picpiclink
      7. 1sje picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-121 [105644] picpiclink
      8. 1t5x picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-121 [106493] picpiclink
      9. 1jws picpicxrefxrefxrefxrefxref
        mutant
        1. region d:1-121 [84246] picpiclink
      10. 1jwm picpicxrefxrefxrefxrefxref
        1. region d:1-121 [84240] picpiclink
      11. 1jck picpicxrefxrefxref
        mutant
        1. region b:1-121 [25196] picpiclink
        2. region d:1-121 [25197] picpiclink
  6. Staphylococcal enterotoxin H, SEH [50230]
    1. Staphylococcus aureus [TaxId: 1280] [50231] (4)
      1. 1enf picpicxref
        complexed with so4
        1. region a:2-101 [25198] picpiclink
      2. 1ewc picpicxref
        complexed with zn
        1. region a:2-101 [25199] picpiclink
      3. 1f77 picpicxref
        complexed with so4
        1. region a:2-101 [25200] picpiclink
        2. region b:2-101 [25201] picpiclink
      4. 1hxy picpicxrefxrefxrefxrefxref
        complexed with zn
        1. region d:2-101 [61390] picpiclink
  7. Superantigen-like protein SET3 [74946]
    1. Staphylococcus aureus [TaxId: 1280] [74947] (3)
      1. 2z8l picpicxref
        automatically matched to d1m4va1
        complexed with fuc, gal, gol, nag, po4, sia
        1. region a:13-100 [154209] picpiclink
      2. 1m4v picpicxref
        1. region a:5-100 [74459] picpiclink
        2. region b:5-100 [74461] picpiclink
      3. 2r61 picpicxref
        automatically matched to d1m4va1
        complexed with cl, fuc, gal, gol, nag, sia, srt
        1. region a:8-100 [151599] picpiclink
  8. Streptococcal superantigen Spe-C [50232]
    1. Streptococcus pyogenes [TaxId: 1314] [50233] (3)
      1. 1an8 picpicxref
        1. region a:3-95 [25202] picpiclink
      2. 1hqr picpicxrefxrefxrefxrefxref
        complexed with zn
        1. region d:503-595 [25203] picpiclink
      3. 1ktk picpicxrefxrefxref
        mutant
        1. region a:3-95 [72976] picpiclink
        2. region b:3-95 [72978] picpiclink
        3. region c:1-95 [72980] picpiclink
        4. region d:3-95 [72982] picpiclink
  9. Streptococcal superantigen Spe-H [50234]
    1. Streptococcus pyogenes [TaxId: 1314] [50235] (2)
      1. 1et9 picpicxref
        1. region a:1-95 [25204] picpiclink
      2. 1eu4 picpicxref
        complexed with zn
        1. region a:1-95 [25205] picpiclink
  10. Streptococcal superantigen Smez-2 [50236]
    1. Streptococcus pyogenes [TaxId: 1314] [50237] (2)
      1. 1eu3 picpicxref
        complexed with k, po4, zn
        1. region a:2a-96 [25206] picpiclink
        2. region b:2-96 [25207] picpiclink
      2. 1et6 picpicxref
        1. region a:1a-95 [25208] picpiclink
        2. region b:4-96 [25209] picpiclink
  11. Streptococcal superantigen SSA [50238]
    1. Streptococcus pyogenes [TaxId: 1314] [50239] (10)
      1. 2aq2 picpicxrefxref
        automatically matched to d1bxta1
        complexed with na, so4, zn; mutant
        1. region b:2-119 [127146] picpiclink
      2. 1bxt picpicxref
        1. region a:1-119 [25210] picpiclink
        2. region b:1-119 [25211] picpiclink
      3. 2aq1 picpicxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region b:2-119 [127138] picpiclink
      4. 2aq1 picpicxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region d:2-119 [127140] picpiclink
      5. 2aq1 picpicxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region f:2-119 [127142] picpiclink
      6. 2aq1 picpicxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region h:2-119 [127144] picpiclink
      7. 2aq3 picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region b:2-119 [127148] picpiclink
      8. 2aq3 picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region d:2-119 [127150] picpiclink
      9. 2aq3 picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region f:2-119 [127152] picpiclink
      10. 2aq3 picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1bxta1
        mutant
        1. region h:2-119 [127154] picpiclink
  12. Streptococcal pyrogenic exotoxin A1 [50240]
    1. Streptococcus pyogenes [TaxId: 1314] [50241] (8)
      SQ P08095
      1. 1fnu picpicxref
        complexed with cd
        1. region a:1-107 [25212] picpiclink
        2. region b:301-407 [25213] picpiclink
        3. region c:601-707 [25214] picpiclink
        4. region d:901-1007 [25215] picpiclink
      2. 1uup picpicxref
        complexed with zn
        1. region a:1001-1107 [108050] picpiclink
        2. region b:2001-2107 [108052] picpiclink
        3. region c:3001-3107 [108054] picpiclink
        4. region d:4001-4107 [108056] picpiclink
      3. 1l0y picpicxrefxrefxref
        complexed with cry, zn; mutant
        1. region b:1-107 [73442] picpiclink
        2. region d:1-107 [73446] picpiclink
      4. 1b1z picpicxref
        1. region a:3-107 [25216] picpiclink
        2. region b:3-107 [25217] picpiclink
        3. region c:3-107 [25218] picpiclink
        4. region d:3-107 [25219] picpiclink
      5. 1ha5 picpicxref
        complexed with zn
        1. region a:1003-1107 [70927] picpiclink
        2. region b:2003-2107 [70929] picpiclink
        3. region c:3003-3107 [70931] picpiclink
        4. region d:4003-4107 [70933] picpiclink
      6. 1l0x picpicxrefxrefxref
        complexed with cry; mutant
        1. region b:1-107 [73434] picpiclink
        2. region d:1-107 [73438] picpiclink
      7. 1fnv picpicxref
        complexed with cd
        1. region a:1-107 [25220] picpiclink
        2. region b:301-407 [25221] picpiclink
        3. region c:601-707 [25222] picpiclink
        4. region d:901-1007 [25223] picpiclink
      8. 1fnw picpicxref
        complexed with cd
        1. region a:1-107 [25224] picpiclink
        2. region b:301-407 [25225] picpiclink
        3. region c:601-707 [25226] picpiclink
        4. region d:901-1007 [25227] picpiclink
        5. region e:1201-1307 [25228] picpiclink
        6. region f:1501-1607 [25229] picpiclink
        7. region g:1801-1907 [25230] picpiclink
        8. region h:2101-2207 [25231] picpiclink
  13. Exotoxin 1 (SET1, Superantigen-like protein 7) [110190]
    1. Staphylococcus aureus [TaxId: 1280] [110191] (2)
      SQ Q9ZFS5 36-231
      1. 1v1o picpicxref
        1. region a:18-108 [108264] picpiclink
        2. region b:18-108 [108266] picpiclink
      2. 1v1p picpicxref
        1. region a:21-108 [108268] picpiclink
        2. region b:23-108 [108270] picpiclink
  14. Streptococcal pyrogenic exotoxin Spe-J [110192]
    1. Streptococcus pyogenes [TaxId: 1314] [110193] (2)
      SQ Q7BAE3
      1. 1ty0 picpicxref
        1. region a:4-99 [107440] picpiclink
        2. region b:4-98 [107442] picpiclink
        3. region c:4-99 [107444] picpiclink
      2. 1ty2 picpicxref
        complexed with zn
        1. region a:4-99 [107446] picpiclink
        2. region b:4-98 [107448] picpiclink
        3. region c:4-99 [107450] picpiclink
  15. Enterotoxin type I, SEI [159080]
    1. Staphylococcus aureus [TaxId: 1280] [159081] (1)
      SQ Q52T95 4-86
      1. 2g9h picpicxrefxrefxrefxrefxref
        complexed with dio, epe, so4, zn
        1. region d:4-86 [145188] picpiclink

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