Structural Classification of Proteins

Superfamily: Chromo domain-like

: SH3-like barrel is capped by a C-terminal helix
uperfamily

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: SH3-like barrel [50036]
barrel, partly opened; n*=4, S*=8; meander
the last strand is interrupted by a turn of 3-10 helix
Superfamily: Chromo domain-like [54160]
SH3-like barrel is capped by a C-terminal helix
uperfamily

Families:

"Histone-like" proteins from archaea [54161] (2)
1. DNA-binding protein [54162]
  1. Archaeon Sulfolobus solfataricus, Sso7d [TaxId: 2287] [54163] (8)
    SQ P61991
  2. Archaeon Sulfolobus acidocaldarius, Sac7d [TaxId: 2285] [54164] (10)
    SQ P13123
Chromo domain [54165] (10)
lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold
1. Heterochromatin protein 1, HP1 [54166]
  duplication: consists of two homologous domains, N-terminal chromo domain and C-terminal chromo shadow domain
  1. Mouse (Mus musculus), HP1 beta (MOD1, M31) [TaxId: 10090] [54167] (8)
  2. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [75343] (3)
    SQ P05205 23-74
  3. Fission yeast (Schizosaccharomyces pombe), SWI6 [TaxId: 4896] [54169] (1)
2. Polycomb protein, Pc [101688]
  1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [101689] (2)
3. Histone methyltransferase clr4, chromo domain [64217]
  1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [64218] (1)
4. Chromobox protein homolog 8 [141214]
  Polycomb 3 homolog, Pc3
  1. Mouse (Mus musculus) [TaxId: 10090] [141215] (1)
    SQ Q9QXV1 7-58
5. CpSRP43 [141216]
  Signal recognition particle 43 kDa protein, chloroplast precursor (CAO)
  1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [141217] (6)
    SQ O22265 265-319! SQ O22265 320-373! SQ O22265 84-128
6. Chromodomain protein, Y-like isoform [141218]
  1. Human (Homo sapiens) [TaxId: 9606] [141219] (1)
    SQ Q32NC5 1-66
7. ATP-dependent helicase CHD1 (Chromo domain protein 1) [141220]
  1. Human (Homo sapiens) [TaxId: 9606] [141221] (25)
    SQ O14646 269-366! SQ O14646 270-355! SQ O14646 366-445! SQ O14646 367-443! SQ O14646 367-445
  2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141222] (2)
    SQ P32657 172-252! SQ P32657 249-347
Chromo barrel domain [117157] (3)
typical SH3-like barrel fold; similar sequence motif to the canonical chromo domain
1. Probable histone acetyltransferase MYST1 [117158]
  1. Mouse (Mus musculus) [TaxId: 10090] [117159] (1)
    SQ Q9D1P2 49-169
2. Putative histone acetyltransferase MOF [141223]
  Males-absent on the first protein
  1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [141224] (1)
    SQ O02193 367-454
3. Mortality factor 4-like protein 1, MRG15 [141225]
  MORF-related gene 15 isoform 1
  1. Human (Homo sapiens) [TaxId: 9606] [141226] (7)
    SQ Q9UBU8 6-88