Structural Classification of Proteins
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Superfamily: Chromo domain-like

SH3-like barrel is capped by a C-terminal helix
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: SH3-like barrel [50036]
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. Superfamily: Chromo domain-like [54160]
    SH3-like barrel is capped by a C-terminal helix
    link to SUPERFAMILY database - Superfamily

Families:

  1. "Histone-like" proteins from archaea [54161] (2)
    1. DNA-binding protein [54162]
      1. Archaeon Sulfolobus solfataricus, Sso7d [TaxId: 2287] [54163] (8)
        SQ P61991
        1. 1bf4 picpic
          protein/DNA complex; complexed with 5iu
          1. chain a [37461] picpiclink
        2. 1c8c picpic
          1. chain a [59084] picpiclink
        3. 1r83 picpic
          Sso7a variant
          mutant
          1. chain a [111717] picpiclink
        4. 2cvr picpic
          automatically matched to d1r83a_
          mutant
          1. region a:1-62 [130889] picpiclink
        5. 1jic picpic
          1. chain a [37462] picpiclink
        6. 1b4o picpic
          1. chain a [37464] picpiclink
        7. 1sso picpic
          1. chain a [37463] picpiclink
        8. 1bbx picpic
          protein/DNA complex
          1. chain c [37465] picpiclink
          2. chain d [37466] picpiclink
      2. Archaeon Sulfolobus acidocaldarius, Sac7d [TaxId: 2285] [54164] (10)
        SQ P13123
        1. 1azp picpic
          protein/DNA complex
          1. chain a [37467] picpiclink
        2. 1bnz picpic
          1. chain a [37468] picpiclink
        3. 1wd0 picpic
          1. chain a [109230] picpiclink
        4. 1azq picpic
          protein/DNA complex
          1. chain a [37469] picpiclink
        5. 1ca6 picpic
          1. chain a [37470] picpiclink
        6. 1wd1 picpic
          1. chain a [109231] picpiclink
        7. 1wvl picpic
          automatically matched to d1azpa_
          1. region a:1-66 [121343] picpiclink
        8. 1wvl picpic
          automatically matched to d1azpa_
          1. region b:1-66 [121344] picpiclink
        9. 1ca5 picpic
          1. chain a [37471] picpiclink
        10. 1sap picpic
          1. chain a [37472] picpiclink
  2. Chromo domain [54165] (10)
    lacks the SH3-like barrel first strand that can be complemented by bound peptide ligand; in shadow chromo domain the corresponding site is altered by insertion; similarity to the IL8-like fold
    1. Heterochromatin protein 1, HP1 [54166]
      duplication: consists of two homologous domains, N-terminal chromo domain and C-terminal chromo shadow domain
      1. Mouse (Mus musculus), HP1 beta (MOD1, M31) [TaxId: 10090] [54167] (8)
        1. 2fmm picpicxref
          automatically matched to d1s4za_
          complexed with so4
          1. region a:108-175 [133782] picpiclink
        2. 2fmm picpicxref
          automatically matched to d1s4za_
          complexed with so4
          1. region b:109-175 [133783] picpiclink
        3. 2fmm picpicxref
          automatically matched to d1s4za_
          complexed with so4
          1. region c:109-175 [133784] picpiclink
        4. 2fmm picpicxref
          automatically matched to d1s4za_
          complexed with so4
          1. region d:110-175 [133785] picpiclink
        5. 1dz1 picpic
          C-terminal shadow chromo domain
          1. chain a [37473] picpiclink
          2. chain b [37474] picpiclink
        6. 1guw picpic
          Chromo domain complexed with the lysine 9-methyl histone H3 N-terminal peptide
          complexed with mly
          1. chain a [70584] picpiclink
        7. 1s4z picpic
          Chromo shadow domain complexed with pxvxl motif peptide of caf-1, chain C
          1. chain a [98515] picpiclink
          2. chain b [98516] picpiclink
        8. 1ap0 picpic
          N-terminal chromo domain
          mutant
          1. chain a [37475] picpiclink
      2. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [75343] (3)
        SQ P05205 23-74
        1. 1q3l picpic
          complexed with histone H3 tail containing monomethyllysine 9 (SQ P16106 5-10), chain P
          complexed with mlz
          1. chain a [111652] picpiclink
        2. 1kna picpic
          Chromo domain complexed with histone h3 tail containing dimethyllysine 9
          complexed with mly; mutant
          1. chain a [72771] picpiclink
        3. 1kne picpic
          Chromo domain complexed with histone h3 tail containing trimethyllysine 9
          complexed with m3l; mutant
          1. chain a [72774] picpiclink
      3. Fission yeast (Schizosaccharomyces pombe), SWI6 [TaxId: 4896] [54169] (1)
        1. 1e0b picpic
          C-terminal shadow chromo domain
          complexed with 1pg
          1. chain a [37476] picpiclink
          2. chain b [37477] picpiclink
    2. Polycomb protein, Pc [101688]
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [101689] (2)
        1. 1pfb picpic
          complexed with histone H3 peptide containing trimethyllysine 27, chain B
          complexed with acy, bme, cl, m3l
          1. chain a [94655] picpiclink
        2. 1pdq picpic
          complexed with histone H3 peptide containing trimethyllysine 27, chain B
          complexed with m3l; mutant
          1. chain a [94590] picpiclink
    3. Histone methyltransferase clr4, chromo domain [64217]
      1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [64218] (1)
        1. 1g6z picpic
          1. chain a [60321] picpiclink
    4. Chromobox protein homolog 8 [141214]
      Polycomb 3 homolog, Pc3
      1. Mouse (Mus musculus) [TaxId: 10090] [141215] (1)
        SQ Q9QXV1 7-58
        1. 2dnv picpic
          1. region a:7-58 [131594] picpiclink
    5. CpSRP43 [141216]
      Signal recognition particle 43 kDa protein, chloroplast precursor (CAO)
      1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [141217] (6)
        SQ O22265 265-319! SQ O22265 320-373! SQ O22265 84-128
        1. 3deo picpicxref
          automatically matched to d1x32a1
          complexed with mg
          1. region a:85-128 [157592] picpiclink
        2. 3dep picpicxref
          automatically matched to d1x32a1
          complexed with cl
          1. region a:85-128 [157594] picpiclink
        3. 2hug picpic
          automatically matched to d1x3qa1
          1. region a:3-57 [147404] picpiclink
        4. 1x3p picpic
          1. region a:1-54 [121668] picpiclink
        5. 1x3q picpic
          1. region a:3-57 [121669] picpiclink
        6. 1x32 picpic
          1. region a:3-47 [121654] picpiclink
    6. Chromodomain protein, Y-like isoform [141218]
      1. Human (Homo sapiens) [TaxId: 9606] [141219] (1)
        SQ Q32NC5 1-66
        1. 2dnt picpic
          1. region a:8-73 [131593] picpiclink
    7. ATP-dependent helicase CHD1 (Chromo domain protein 1) [141220]
      1. Human (Homo sapiens) [TaxId: 9606] [141221] (25)
        SQ O14646 269-366! SQ O14646 270-355! SQ O14646 366-445! SQ O14646 367-443! SQ O14646 367-445
        1. 2b2y picpic
          automatically matched to 2B2T C:12-97
          1. region c:12-96 [127758] picpiclink
        2. 2b2y picpic
          automatically matched to 2B2U A:108-187
          1. region a:108-187 [127754] picpiclink
        3. 2b2y picpic
          automatically matched to 2B2U A:13-107
          1. region a:13-107 [127755] picpiclink
        4. 2b2y picpic
          automatically matched to 2B2U A:108-187
          1. region b:108-186 [127756] picpiclink
        5. 2b2y picpic
          automatically matched to 2B2U A:13-107
          1. region b:13-107 [127757] picpiclink
        6. 2b2w picpic
          automatically matched to 2B2T C:12-97
          complexed with m3l
          1. region c:12-96 [127747] picpiclink
        7. 2b2w picpic
          automatically matched to 2B2U A:108-187
          complexed with m3l
          1. region a:108-187 [127743] picpiclink
        8. 2b2w picpic
          automatically matched to 2B2U A:13-107
          complexed with m3l
          1. region a:13-107 [127744] picpiclink
        9. 2b2w picpic
          automatically matched to 2B2U A:108-187
          complexed with m3l
          1. region b:108-186 [127745] picpiclink
        10. 2b2w picpic
          automatically matched to 2B2U A:13-107
          complexed with m3l
          1. region b:13-107 [127746] picpiclink
        11. 2b2t picpic
          complexed with m3l; mutant
          1. region c:12-97 [127732] picpiclink
        12. 2b2t picpic
          complexed with m3l; mutant
          1. region a:11-107 [127728] picpiclink
        13. 2b2t picpic
          complexed with m3l; mutant
          1. region a:109-186 [127729] picpiclink
        14. 2b2t picpic
          automatically matched to 2B2T A:11-107
          complexed with m3l; mutant
          1. region b:11-107 [127730] picpiclink
        15. 2b2t picpic
          automatically matched to 2B2T A:109-186
          complexed with m3l; mutant
          1. region b:109-186 [127731] picpiclink
        16. 2b2v picpic
          automatically matched to 2B2T C:12-97
          complexed with mlz
          1. region c:13-97 [127742] picpiclink
        17. 2b2v picpic
          automatically matched to 2B2U A:108-187
          complexed with mlz
          1. region a:108-186 [127738] picpiclink
        18. 2b2v picpic
          automatically matched to 2B2U A:13-107
          complexed with mlz
          1. region a:13-107 [127739] picpiclink
        19. 2b2v picpic
          automatically matched to 2B2U A:108-187
          complexed with mlz
          1. region b:108-185 [127740] picpiclink
        20. 2b2v picpic
          automatically matched to 2B2U A:13-107
          complexed with mlz
          1. region b:13-107 [127741] picpiclink
        21. 2b2u picpic
          complexed with da2, m3l
          1. region a:108-187 [127733] picpiclink
        22. 2b2u picpic
          complexed with da2, m3l
          1. region a:13-107 [127734] picpiclink
        23. 2b2u picpic
          automatically matched to 2B2T C:12-97
          complexed with da2, m3l
          1. region c:13-97 [127737] picpiclink
        24. 2b2u picpic
          automatically matched to 2B2U A:108-187
          complexed with da2, m3l
          1. region b:108-185 [127735] picpiclink
        25. 2b2u picpic
          automatically matched to 2B2U A:13-107
          complexed with da2, m3l
          1. region b:13-107 [127736] picpiclink
      2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [141222] (2)
        SQ P32657 172-252! SQ P32657 249-347
        1. 2dy8 picpic
          2nd chromodomain
          1. region a:279-347 [131892] picpiclink
        2. 2dy7 picpic
          1st chromodomain
          1. region a:172-252 [131891] picpiclink
  3. Chromo barrel domain [117157] (3)
    typical SH3-like barrel fold; similar sequence motif to the canonical chromo domain
    1. Probable histone acetyltransferase MYST1 [117158]
      1. Mouse (Mus musculus) [TaxId: 10090] [117159] (1)
        SQ Q9D1P2 49-169
        1. 1wgs picpic
          Structural genomics target
          1. chain a [114622] picpiclink
    2. Putative histone acetyltransferase MOF [141223]
      Males-absent on the first protein
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [141224] (1)
        SQ O02193 367-454
        1. 2bud picpic
          1. region a:367-454 [129190] picpiclink
    3. Mortality factor 4-like protein 1, MRG15 [141225]
      MORF-related gene 15 isoform 1
      1. Human (Homo sapiens) [TaxId: 9606] [141226] (7)
        SQ Q9UBU8 6-88
        1. 2f5k picpic
          1. region a:6-88 [132995] picpiclink
        2. 2f5k picpic
          automatically matched to 2F5K A:6-88
          1. region b:6-88 [132996] picpiclink
        3. 2f5k picpic
          automatically matched to 2F5K A:6-88
          1. region c:7-86 [132997] picpiclink
        4. 2f5k picpic
          automatically matched to 2F5K A:6-88
          1. region d:6-84 [132998] picpiclink
        5. 2f5k picpic
          automatically matched to 2F5K A:6-88
          1. region e:6-83 [132999] picpiclink
        6. 2f5k picpic
          automatically matched to 2F5K A:6-88
          1. region f:9-86 [133000] picpiclink
        7. 2efi picpic
          automatically matched to d2f5ka1
          1. region a:13-95 [146814] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk