Structural Classification of Proteins
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Superfamily: ISP domain

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: ISP domain [50021]
    consists of two all-beta subdomains: conserved small domain has a rubredoxin-like fold; larger domain consists of 6 beta-stands packed in either sandwich of two 3-stranded sheets or closed barrel (n=6; S=8)
  4. Superfamily: ISP domain [50022]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Rieske iron-sulfur protein (ISP) [50023] (11)
    1. ISP subunit of the mitochondrial cytochrome bc1-complex, water-soluble domain [50024]
      1. Cow (Bos taurus) [TaxId: 9913] [50025] (10)
        1. 1rie picpic
          complexed with fes
          1. chain a [24427] picpiclink
        2. 1ntm picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hem
          1. region e:70-196 [92129] picpiclink
        3. 1ntz picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hem, uq2
          1. region e:70-196 [92157] picpiclink
        4. 1l0l picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, fmx, hem
          1. region e:70-196 [84490] picpiclink
        5. 1ntk picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with ay1, fes, hem
          1. region e:70-196 [92113] picpiclink
        6. 1l0n picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hem
          1. region e:70-196 [84506] picpiclink
        7. 1nu1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hem, qno
          1. region e:70-196 [92175] picpiclink
        8. 1be3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hec, hem
          1. region e:70-196 [24428] picpiclink
        9. 1bgy picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hec, hem
          1. region q:70-196 [24430] picpiclink
        10. 1qcr picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with hem
          1. region e:70-196 [24429] picpiclink
      2. Chicken (Gallus gallus) [TaxId: 9031] [50026] (6)
        SQ P13272 79-274 ! SQ P13272 # precursor of chains I,E and V,R
        1. 1ppj picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with any, azi, bhg, cdl, fes, gol, hec, hem, pee, po4, sma
          1. region e:70-196 [104260] picpiclink
          2. region r:70-196 [104275] picpiclink
        2. 1pp9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with azi, bhg, cdl, fes, gol, hec, hem, pee, po4, sma, uq
          1. region e:70-196 [104230] picpiclink
          2. region r:70-196 [104245] picpiclink
        3. 1sqb picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with azo, fes, hem
          1. region e:70-196 [105898] picpiclink
        4. 1bcc picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with bog, fes, hem, pee, u10
          1. region e:70-196 [24431] picpiclink
        5. 2bcc picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with bog, fes, hem, pee, sig, u10
          1. region e:70-196 [24432] picpiclink
        6. 3bcc picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with amy, fes, hem, sig
          1. region e:70-196 [24433] picpiclink
      3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [63741] (9)
        1. 3cx5 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ezve1
          complexed with 6ph, 7ph, 8pe, 9pe, cn3, cn5, fes, hem, m3l, sma, suc, umq
          1. region e:87-215 [157084] picpiclink
        2. 3cx5 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ezve1
          complexed with 6ph, 7ph, 8pe, 9pe, cn3, cn5, fes, hem, m3l, sma, suc, umq
          1. region p:87-215 [157100] picpiclink
        3. 1kb9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with cdl, fes, hem, pcf, pef, pie, sma, umq, uq6
          1. region e:87-215 [77319] picpiclink
        4. 2ibz picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ezve1
          complexed with fes, hem, sma, uq6
          1. region e:87-215 [137223] picpiclink
        5. 1ezv picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hem, sma, uq6
          1. region e:87-215 [59548] picpiclink
        6. 3cxh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ezve1
          complexed with 6ph, 7ph, 8pe, 9pe, cn6, fes, hem, m3l, sma, suc, umq
          1. region e:87-215 [157117] picpiclink
        7. 3cxh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1ezve1
          complexed with 6ph, 7ph, 8pe, 9pe, cn6, fes, hem, m3l, sma, suc, umq
          1. region p:87-215 [157133] picpiclink
        8. 1p84 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with 3pe, 3ph, cdl, dbt, fes, hem, pc1, umq, uq6
          1. region e:87-215 [87858] picpiclink
        9. 1kyo picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with fes, hem, m3l, sma
          1. region e:87-215 [73256] picpiclink
          2. region p:87-215 [73271] picpiclink
    2. ISP subunit from the cytochrome b6f complex, soluble domain [101665]
      1. Mastigocladus laminosus [TaxId: 83541] [101666] (6)
        1. 2e74 picpicxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1vf5d1
          complexed with bcr, cd, cla, fes, hem, opc, sqd, umq
          1. region d:46-179 [132049] picpiclink
        2. 1vf5 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with bcr, cla, fes, hem, opc, pl9, tds
          1. region d:46-179 [100583] picpiclink
          2. region q:46-179 [100594] picpiclink
        3. 2e76 picpicxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1vf5d1
          complexed with bcr, cd, cla, fes, hem, opc, sqd, tds, umq
          1. region d:46-179 [132059] picpiclink
        4. 2e75 picpicxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1vf5d1
          complexed with bcr, cd, cla, fes, hem, opc, qno, sqd, umq
          1. region d:46-179 [132054] picpiclink
        5. 2d2c picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1vf5d1
          complexed with bcr, bnt, cla, fes, hec, hem, opc
          1. region d:46-179 [131163] picpiclink
        6. 2d2c picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1vf5d1
          complexed with bcr, bnt, cla, fes, hec, hem, opc
          1. region q:46-179 [131169] picpiclink
      2. Chlamydomonas reinhardtii [TaxId: 3055] [101667] (1)
        1. 1q90 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with bcr, cl1, fes, hem, lfa, lmg, sqd, tds; mutant
          1. chain c [96242] picpiclink
    3. ISP subunit from chloroplast cytochrome bf complex [50027]
      1. Spinach (Spinacia oleracea) [TaxId: 3562] [50028] (1)
        1. 1rfs picpic
          complexed with fes
          1. chain a [24434] picpiclink
    4. Arsenite oxidase Rieske subunit [50029]
      1. Alcaligenes faecalis [TaxId: 511] [50030] (2)
        1. 1g8k picpicxrefxref
          complexed with 4mo, edo, fes, fs3, hg, mgd, oc2, oc6, oxo
          1. chain b [24435] picpiclink
          2. chain d [24436] picpiclink
          3. chain f [24437] picpiclink
          4. chain h [24438] picpiclink
        2. 1g8j picpicxrefxref
          complexed with 4mo, fes, fs3, mgd, oxo
          1. chain b [24439] picpiclink
          2. chain d [24440] picpiclink
    5. Rieske protein II (SoxF) [74918]
      1. Archaeon Sulfolobus acidocaldarius [TaxId: 2285] [74919] (1)
        1. 1jm1 picpic
          complexed with fes, mg
          1. chain a [71745] picpiclink
    6. Soluble Rieske protein [89291]
      1. Thermus thermophilus [TaxId: 274] [89292] (1)
        1. 1nyk picpic
          complexed with fes, mg
          1. chain a [86408] picpiclink
          2. chain b [86409] picpiclink
    7. Rieske-type ferredoxin associated with biphenyl dioxygenase [50031]
      1. Burkholderia cepacia [TaxId: 292] [50032] (1)
        1. 1fqt picpic
          complexed with fes, gol
          1. chain a [24441] picpiclink
          2. chain b [24442] picpiclink
    8. Toluene-4-monooxygenase system protein C, TmoC [110154]
      1. Pseudomonas mendocina [TaxId: 300] [110155] (3)
        SQ Q00458
        1. 1vm9 picpic
          complexed with edo, fes, mg; mutant
          1. chain a [108886] picpiclink
        2. 2q3w picpic
          automatically matched to d1vm9a_
          complexed with edo, fes, mg; mutant
          1. region a:2-110 [139813] picpiclink
        3. 1sjg picpic
          complexed with fes
          1. chain a [105647] picpiclink
  2. Ring hydroxylating alpha subunit ISP domain [50033] (7)
    1. Naphthalene 1,2-dioxygenase alpha subunit, N-domain [50034]
      1. Pseudomonas putida [TaxId: 303] [50035] (16)
        1. 1o7n picpicxrefxref
          complexed with edo, fe, fes, ind, oxy, so4
          1. region a:1-154 [81162] picpiclink
        2. 2hmj picpicxrefxref
          automatically matched to d1eg9a1
          complexed with edo, fe, fes, so4; mutant
          1. region a:1-154 [136585] picpiclink
        3. 2hmo picpicxrefxref
          automatically matched to d1eg9a1
          complexed with 3nt, edo, fe, fes, so4
          1. region a:1-154 [136600] picpiclink
        4. 2hmm picpicxrefxref
          automatically matched to d1eg9a1
          complexed with an3, edo, fe, fes, so4; mutant
          1. region a:1-154 [136594] picpiclink
        5. 2hmk picpicxrefxref
          automatically matched to d1eg9a1
          complexed with edo, fe, fes, pey, so4; mutant
          1. region a:1-154 [136588] picpiclink
        6. 2hmn picpicxrefxref
          automatically matched to d1eg9a1
          complexed with an3, edo, fe, fes, so4; mutant
          1. region a:1-154 [136597] picpiclink
        7. 1eg9 picpicxrefxref
          complexed with fes, ind, of1, so4
          1. region a:1-154 [24443] picpiclink
        8. 1o7g picpicxrefxref
          complexed with edo, fe, fes, npy, so4
          1. region a:1-154 [81134] picpiclink
        9. 1uuv picpicxrefxref
          automatically matched to d1eg9a1
          complexed with edo, fe, fes, ind, no, so4
          1. region a:1-154 [119699] picpiclink
        10. 1o7m picpicxrefxref
          complexed with edo, fe, fes, oxy, so4
          1. region a:1-154 [81159] picpiclink
        11. 2hml picpicxrefxref
          automatically matched to d1eg9a1
          complexed with edo, fe, fes, pey, so4; mutant
          1. region a:1-154 [136591] picpiclink
        12. 1o7w picpicxrefxref
          complexed with edo, fe, fes, so4
          1. region a:1-154 [81168] picpiclink
        13. 1o7p picpicxrefxref
          complexed with edo, fe, fes, ndh, so4
          1. region a:1-154 [81165] picpiclink
        14. 1o7h picpicxrefxref
          complexed with edo, fe, fes, so4
          1. region a:1-154 [81137] picpiclink
        15. 1uuw picpicxrefxref
          automatically matched to d1eg9a1
          complexed with fe, fes, no, so4
          1. region a:1-154 [119702] picpiclink
        16. 1ndo picpicxrefxref
          complexed with fe, fes
          1. region a:1-154 [24444] picpiclink
          2. region c:1-154 [24445] picpiclink
          3. region e:1-154 [24446] picpiclink
      2. Rhodococcus sp. ncimb12038 [TaxId: 92694] [141177] (6)
        SQ Q9X3R9 1-162
        1. 2b1x picpicxrefxrefxrefxrefxrefxref
          complexed with fe, fes, mpd
          1. region a:1-162 [127675] picpiclink
        2. 2b1x picpicxrefxrefxrefxrefxrefxref
          automatically matched to 2B1X A:1-162
          complexed with fe, fes, mpd
          1. region c:1-162 [127678] picpiclink
        3. 2b1x picpicxrefxrefxrefxrefxrefxref
          automatically matched to 2B1X A:1-162
          complexed with fe, fes, mpd
          1. region e:1-162 [127681] picpiclink
        4. 2b24 picpicxrefxrefxrefxrefxrefxref
          automatically matched to 2B1X A:1-162
          complexed with fe, fes, ind
          1. region a:1-162 [127690] picpiclink
        5. 2b24 picpicxrefxrefxrefxrefxrefxref
          automatically matched to 2B1X A:1-162
          complexed with fe, fes, ind
          1. region c:1-162 [127693] picpiclink
        6. 2b24 picpicxrefxrefxrefxrefxrefxref
          automatically matched to 2B1X A:1-162
          complexed with fe, fes, ind
          1. region e:1-162 [127696] picpiclink
    2. Biphenyl dioxygenase large subunit BphA1, N-terminal domain [110156]
      1. Rhodococcus sp. (strain RHA1) [TaxId: 101510] [110157] (2)
        SQ Q53122 17-451
        1. 1uli picpicxrefxref
          complexed with fe2, fes
          1. region a:17-170 [107921] picpiclink
          2. region c:17-170 [107924] picpiclink
          3. region e:17-170 [107927] picpiclink
        2. 1ulj picpicxrefxref
          complexed with bnl, fe2, fes
          1. region a:17-170 [107930] picpiclink
          2. region c:17-170 [107933] picpiclink
          3. region e:17-170 [107936] picpiclink
    3. 2-oxo-1,2-dihydroquinoline 8-monooxygenase, oxygenase component OxoO [141178]
      1. Pseudomonas putida [TaxId: 303] [141179] (1)
        SQ O05935 16-163
        1. 1z01 picpicxref
          complexed with fe, fes
          1. region a:16-163 [124296] picpiclink
    4. Nitrobenzene dioxygenase alpha subunit, NBDO-alpha [141180]
      1. Comamonas sp. JS765 [TaxId: 58226] [141181] (3)
        SQ Q8RTL4 3-152
        1. 2bmo picpicxrefxref
          complexed with edo, eoh, fe, fes, ni
          1. region a:3-152 [128804] picpiclink
        2. 2bmr picpicxrefxref
          automatically matched to 2BMO A:3-152
          complexed with 3nt, edo, eoh, fe, fes, ni
          1. region a:3-152 [128810] picpiclink
        3. 2bmq picpicxrefxref
          automatically matched to 2BMO A:3-152
          complexed with edo, eoh, fe, fes, nbz, ni
          1. region a:3-152 [128807] picpiclink
    5. Large subunit of cumene dioxygenase cumA1 [141182]
      1. Pseudomonas fluorescens [TaxId: 294] [141183] (1)
        SQ Q51743 19-180
        1. 1wql picpicxrefxref
          complexed with fe2, fes, oxy
          1. region a:19-180 [121170] picpiclink
    6. Terminal oxygenase component of carbazole CarAa [141184]
      1. Janthinobacterium sp. j3 [TaxId: 213804] [141185] (10)
        SQ Q84II6 1-142
        1. 2de6 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with fe2, fes
          1. region a:1-142 [131415] picpiclink
        2. 2de6 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with fe2, fes
          1. region b:1-142 [131417] picpiclink
        3. 2de6 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with fe2, fes
          1. region c:1-142 [131419] picpiclink
        4. 2de5 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with fe2, fes
          1. region a:1-142 [131409] picpiclink
        5. 2de5 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with fe2, fes
          1. region b:1-142 [131411] picpiclink
        6. 2de5 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with fe2, fes
          1. region c:1-142 [131413] picpiclink
        7. 1ww9 picpicxref
          complexed with fe2, fes
          1. region a:1-142 [121352] picpiclink
        8. 2de7 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with 9ca, fe2, fes
          1. region a:1-142 [131421] picpiclink
        9. 2de7 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with 9ca, fe2, fes
          1. region b:1-142 [131423] picpiclink
        10. 2de7 picpicxrefxrefxref
          automatically matched to 1WW9 A:1-142
          complexed with 9ca, fe2, fes
          1. region c:1-142 [131425] picpiclink
  3. NirD-like [158991] (3)
    retains the common fold but lacks the Fe-S cluster
    1. NADH-nitrite reductase small subunit NirD [158992]
      1. Escherichia coli [TaxId: 562] [158993] (1)
        SQ P0A9I8 1-108
        1. 2jo6 picpic
          1. region a:1-108 [148154] picpiclink
      2. Erwinia carotovora [TaxId: 554] [158994] (1)
        SQ Q6CZS1 1-122
        1. 2jza picpic
          1. region a:1-122 [148246] picpiclink
      3. Vibrio parahaemolyticus [TaxId: 670] [158995] (8)
        SQ Q87HB1 4-111
        1. 3c0d picpic
          1. region a:4-111 [155819] picpiclink
        2. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region b:4-110 [155820] picpiclink
        3. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region c:4-109 [155821] picpiclink
        4. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region d:4-109 [155822] picpiclink
        5. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region e:4-109 [155823] picpiclink
        6. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region f:4-109 [155824] picpiclink
        7. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region g:4-109 [155825] picpiclink
        8. 3c0d picpic
          automatically matched to 3C0D A:4-111
          1. region h:4-109 [155826] picpiclink

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