Structural Classification of Proteins
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Family: Intein (protein splicing domain)

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Hedgehog/intein (Hint) domain [51293]
    complex fold made of five beta-hairpin units and a b-ribbon arc
  4. Superfamily: Hedgehog/intein (Hint) domain [51294]
    duplication: contains two intertwined structural repeats
    link to SUPERFAMILY database - Superfamily
  5. Family: Intein (protein splicing domain) [51298]

Protein Domains:

  1. VMA1-derived endonuclease (VDE) PI-Scei intein [51299]
    also contains a homing endonuclease and DNA-binding domains
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [51300] (8)
      SQ P17255 284-737
      1. 1gpp picpic
        domain I only
        mutant
        1. chain a [76262] picpiclink
      2. 1jva picpicxref
        contains the N and C extein propeptides
        mutant
        1. region a:282-463,a:699-741 [77175] picpiclink
        2. region b:279-463,b:699-741 [77178] picpiclink
      3. 1ef0 picpicxref
        miniprecursor; a few extra residues are added at the N-terminus
        complexed with zn
        1. region a:1-180,a:416-455 [28376] picpiclink
        2. region b:1-180,b:416-458 [28377] picpiclink
      4. 1dfa picpicxref
        1. region a:1-180,a:416-454 [28375] picpiclink
      5. 1vde picpicxref
        1. region a:1-180,a:416-454 [28378] picpiclink
        2. region b:1-180,b:416-454 [28379] picpiclink
      6. 1um2 picpicxref
        complexed with the ligated extein segment (SQ P17255 281-283,738-741), chains C and D
        mutant
        1. region a:284-463,a:699-737 [107946] picpiclink
        2. region b:284-463,b:699-737 [107949] picpiclink
      7. 1lwt picpicxref
        complexed with mse
        1. region a:1-180,a:416-454 [78278] picpiclink
      8. 1lws picpicxref
        complexed with ca, mse
        1. region a:1-180,a:416-454 [78275] picpiclink
  2. PI-Pfui intein [51301]
    1. Archaeon Pyrococcus furiosus [TaxId: 2261] [51302] (1)
      1. 1dq3 picpicxrefxref
        complexed with zn
        1. region a:1-128,a:415-454 [28380] picpiclink
  3. GyrA intein [51303]
    miniintein lacking the homing endonuclease domain
    1. Mycobacterium xenopi [TaxId: 1789] [51304] (1)
      1. 1am2 picpic
        mutant
        1. chain a [28381] picpiclink
  4. DnaB intein [102011]
    miniintein lacking the homing endonuclease domain
    1. Synechocystis sp. pcc 6803 [TaxId: 1148] [102012] (1)
      1. 1mi8 picpic
        1. chain a [91279] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk