Structural Classification of Proteins
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Family: dTDP-sugar isomerase

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Double-stranded beta-helix [51181]
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. Superfamily: RmlC-like cupins [51182]
    link to SUPERFAMILY database - Superfamily
  5. Family: dTDP-sugar isomerase [51183]

Protein Domains:

  1. dTDP-4-dehydrorhamnose 3,5-epimerase RmlC [51184]
    synonym: dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
    1. Salmonella typhimurium [TaxId: 90371] [51185] (2)
      1. 1dzr picpic
        complexed with gol, so4
        1. chain a [28076] picpiclink
        2. chain b [28077] picpiclink
      2. 1dzt picpic
        complexed with aty, gol, so4, tpe
        1. chain a [28078] picpiclink
        2. chain b [28079] picpiclink
    2. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [51186] (2)
      1. 1ep0 picpic
        1. chain a [28080] picpiclink
      2. 1epz picpic
        complexed with tyd
        1. chain a [28081] picpiclink
    3. Streptococcus suis [TaxId: 1307] [89402] (7)
      1. 1nxm picpic
        1. chain a [86385] picpiclink
        2. chain b [86386] picpiclink
      2. 2ixl picpic
        automatically matched to d1nzca_
        complexed with ni, trh
        1. region a:2-197 [137772] picpiclink
      3. 2ixl picpic
        automatically matched to d1nzca_
        complexed with ni, trh
        1. region b:3-197 [137773] picpiclink
      4. 2ixl picpic
        automatically matched to d1nzca_
        complexed with ni, trh
        1. region c:2-197 [137774] picpiclink
      5. 2ixl picpic
        automatically matched to d1nzca_
        complexed with ni, trh
        1. region d:2-197 [137775] picpiclink
      6. 1nyw picpic
        complexed with dau
        1. chain a [86429] picpiclink
        2. chain b [86430] picpiclink
      7. 1nzc picpic
        complexed with ni, tdx
        1. chain a [86445] picpiclink
        2. chain b [86446] picpiclink
        3. chain c [86447] picpiclink
        4. chain d [86448] picpiclink
    4. Mycobacterium tuberculosis [TaxId: 1773] [101971] (6)
      1. 2ixc picpic
        automatically matched to d1upia_
        complexed with trh
        1. region a:1-198 [137765] picpiclink
      2. 2ixc picpic
        automatically matched to d1upia_
        complexed with trh
        1. region b:1-198 [137766] picpiclink
      3. 2ixc picpic
        automatically matched to d1upia_
        complexed with trh
        1. region c:1-198 [137767] picpiclink
      4. 2ixc picpic
        automatically matched to d1upia_
        complexed with trh
        1. region d:1-198 [137768] picpiclink
      5. 1upi picpic
        1. chain a [99757] picpiclink
      6. 1pm7 picpic
        complexed with act, gol
        1. chain a [94895] picpiclink
        2. chain b [94896] picpiclink
    5. Pseudomonas aeruginosa [TaxId: 287] [101972] (4)
      1. 2ixh picpic
        automatically matched to d1rtva_
        complexed with trh
        1. region a:1-184 [137769] picpiclink
      2. 2ixh picpic
        automatically matched to d1rtva_
        complexed with trh
        1. region b:1-184 [137770] picpiclink
      3. 2ixj picpic
        automatically matched to d1rtva_
        complexed with srt
        1. region a:1-184 [137771] picpiclink
      4. 1rtv picpic
        complexed with tar
        1. chain a [97822] picpiclink
    6. Archaeon Sulfolobus tokodaii [TaxId: 111955] [141586] (2)
      SQ Q96Z62 1-176
      1. 1wlt picpic
        1. region a:1-176 [121013] picpiclink
      2. 1wlt picpic
        automatically matched to 1WLT A:1-176
        1. region b:1-176 [121014] picpiclink
  2. dTDP-4-keto-6-deoxy-glucose-5-epimerase EvaD [101973]
    1. Amycolatopsis orientalis [TaxId: 31958] [101974] (2)
      SQ O52806
      1. 1oi6 picpic
        complexed with gol, tmp
        1. chain a [103940] picpiclink
        2. chain b [103941] picpiclink
      2. 1ofn picpic
        complexed with gol
        1. chain a [92830] picpiclink
        2. chain b [92831] picpiclink
  3. Novobiocin biosynthesis protein NovW [141587]
    1. Streptomyces caeruleus [TaxId: 195949] [141588] (1)
      SQ Q9L9E5 1-190
      1. 2c0z picpic
        complexed with edo, so4
        1. region a:1-190 [129615] picpiclink
  4. dTDP-6-deoxy-3,4-keto-hexulose isomerase FdtA [159287]
    1. Aneurinibacillus thermoaerophilus [TaxId: 143495] [159288] (8)
      SQ Q6T1W8 1-136! SQ Q6T1W8 2-136
      1. 2pa7 picpic
        complexed with cl, edo, tyd
        1. region a:2-136 [149339] picpiclink
      2. 2pa7 picpic
        automatically matched to 2PA7 A:2-136
        complexed with cl, edo, tyd
        1. region b:2-135 [149340] picpiclink
      3. 2pak picpic
        complexed with tyd; mutant
        1. region a:2-136 [149346] picpiclink
      4. 2pae picpic
        complexed with tyd; mutant
        1. region a:1-136 [149341] picpiclink
      5. 2pam picpic
        complexed with tyd; mutant
        1. region a:2-136 [149348] picpiclink
      6. 2pae picpic
        automatically matched to 2PAE A:1-136
        complexed with tyd; mutant
        1. region b:2-135 [149342] picpiclink
      7. 2pak picpic
        automatically matched to 2PAK A:2-136
        complexed with tyd; mutant
        1. region b:2-135 [149347] picpiclink
      8. 2pam picpic
        automatically matched to 2PAM A:2-136
        complexed with tyd; mutant
        1. region b:2-135 [149349] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk