Structural Classification of Proteins
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Superfamily: Fibronectin type III

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Fibronectin type III [49265]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Fibronectin type III [49266] (53)
    Pfam 00041
    1. Extracellular region of human tissue factor [49267]
      tandem of fibronectin type III domains
      1. Human (Homo sapiens) [TaxId: 9606] [49268] (13) picpic
        SQ P13726 33-242
      2. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [49269] (35) picpic
    2. Fibronectin, different Fn3 modules [49270]
      1. Human (Homo sapiens) [TaxId: 9606] [49271] (9) picpic
      2. Mouse (Mus musculus) [TaxId: 10090] [49272] (2) picpic
      3. Escherichia coli K12 (Escherichia coli K-12) [TaxId: 83333] [158899] (1) picpic
    3. Tenascin [49273]
      1. Chicken (Gallus gallus) [TaxId: 9031] [49274] (1) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [49275] (1) picpic
      3. Rat (Rattus norvegicus) [TaxId: 10116] [110057] (1) picpic
        SQ Q05546 502-770
    4. Neuroglian, two amino proximal Fn3 repeats [49276]
      tandem of fibronectin type III domains
      1. Drosophila melanogaster [TaxId: 7227] [49277] (1) picpic
    5. Neural cell adhesion molecule 1, NCAM [89197]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [89198] (1) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [141033] (17) picpic
        SQ P13592 498-598
    6. Fibronectin type III domain from chitinase A1. [81975]
      1. Bacillus circulans [TaxId: 1397] [81976] (1) picpic
    7. Integrin beta-4 subunit [49278]
      1. Human (Homo sapiens) [TaxId: 9606] [49279] (1) picpic
    8. Growth hormone receptor [49280]
      1. Human (Homo sapiens) [TaxId: 9606] [49281] (10) picpic
        tandem of fibronectin type III domains
    9. Erythropoietin (EPO) receptor [49282]
      1. Human (Homo sapiens) [TaxId: 9606] [49283] (5) picpic
      2. Escherichia coli [TaxId: 562] [158900] (6) picpic
    10. Prolactin receptor [49284]
      1. Human (Homo sapiens) [TaxId: 9606] [49285] (3) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [49286] (1) picpic
    11. Interleukin-4 receptor alpha chain [49287]
      1. Human (Homo sapiens) [TaxId: 9606] [49288] (1) picpic
    12. Common beta-chain in the GM-CSF, IL-3 and IL-5 receptors [49289]
      duplication: consists of four similar domains; dimerizes by swapping the C-terminal strands of domains 1 and 3
      1. Human (Homo sapiens) [TaxId: 9606] [49290] (11) picpic
    13. Granulocyte colony-stimulating factor (GC-SF) receptor [49291]
      1. Mouse (Mus musculus) [TaxId: 10090] [49292] (4) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [141034] (2) picpic
        SQ Q99062 120-226! SQ Q99062 227-331
    14. Interferon-gamma receptor alpha chain [49293]
      1. Human (Homo sapiens) [TaxId: 9606] [49294] (3) picpic
    15. Cytokine receptor gp130 cytokine-binding domains [49295]
      1. Human (Homo sapiens) [TaxId: 9606] [49296] (5) picpic
    16. Interleukin-10 receptor 1, IL-10R1 [63670]
      1. Human (Homo sapiens) [TaxId: 9606] [63671] (8) picpic
    17. Type I titin module [49297]
      1. Human (Homo sapiens) [TaxId: 9606] [49298] (1) picpic
    18. The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672]
      1. Human (Homo sapiens) [TaxId: 9606] [63673] (12) picpic
    19. Interleukin-6 receptor alpha chain, domains 2 and 3 [81977]
      1. Human (Homo sapiens) [TaxId: 9606] [81978] (3) picpic
    20. Interferon-alpha/beta receptor beta chain [89199]
      1. Human (Homo sapiens) [TaxId: 9606] [89200] (4) picpic
    21. KIAA1568 protein [101529]
      1. Human (Homo sapiens) [TaxId: 9606] [101530] (2) picpic
    22. KIAA0343 protein [101531]
      1. Human (Homo sapiens) [TaxId: 9606] [101532] (2) picpic
    23. KIAA1355 [110058]
      1. Human (Homo sapiens) [TaxId: 9606] [110059] (1) picpic
        SQ Q9P2J2 [Fragment] 634-728
    24. Ciliary neurotrophic factor receptor alpha [110060]
      1. Human (Homo sapiens) [TaxId: 9606] [110061] (1) picpic
        SQ P26992 202-305
    25. Host cell factor 2, HCF-2 [117051]
      1. Mouse (Mus musculus) [TaxId: 10090] [117052] (1) picpic
        SQ Q9D968 127-236
    26. Fibronectin type 3 and ankyrin repeat domains 1 protein, FANK1 [117053]
      1. Mouse (Mus musculus) [TaxId: 10090] [117054] (1) picpic
        SQ Q9DAM9 1-107
    27. Contactin 3 (KIAA1496) [117055]
      1. Human (Homo sapiens) [TaxId: 9606] [117056] (1) picpic
        SQ Q9P232 893-996
    28. Fibronectin type-III domain containing protein 3a, FNDC3A (KIAA0970) [117057]
      1. Human (Homo sapiens) [TaxId: 9606] [117058] (6) picpic
        SQ Q9Y2H6 192-315
    29. Ephrin type-B receptor 1 [141035]
      1. Human (Homo sapiens) [TaxId: 9606] [141036] (1) picpic
        SQ P54762 434-528
    30. Brother of CDO precursor (BOC) [141037]
      1. Mouse (Mus musculus) [TaxId: 10090] [141038] (2) picpic
        SQ Q6AZB0 591-689! SQ Q6AZB0 707-807
    31. Ephrin type-A receptor 8 [141039]
      1. Human (Homo sapiens) [TaxId: 9606] [141040] (1) picpic
        SQ P29322 473-534
        structure of the C-terminal SAM domain is known (scop_sp 101243)
    32. Cytokine receptor common gamma chain [141041]
      1. Human (Homo sapiens) [TaxId: 9606] [141042] (8) picpic
        SQ P31785 142-246! SQ P31785 142-248! SQ P31785 54-141! SQ P31785 56-141
    33. Rim binding protein 2 [141043]
      1. Human (Homo sapiens) [TaxId: 9606] [141044] (1) picpic
        SQ O15034 477-593
    34. Tenascin-X [141045]
      1. Human (Homo sapiens) [TaxId: 9606] [141046] (3) picpic
        SQ P22105 3699-3798! SQ P22105 3890-3991! SQ P22105 3977-4069
    35. Interleukin-2 receptor beta chain [141047]
      1. Human (Homo sapiens) [TaxId: 9606] [141048] (6) picpic
        SQ P14784 130-232! SQ P14784 130-233! SQ P14784 32-129
    36. Receptor-type tyrosine-protein phosphatase delta, PTPRD [141049]
      1. Human (Homo sapiens) [TaxId: 9606] [141050] (1) picpic
        SQ P23468 504-607
    37. Sidekick 2 [141051]
      1. Human (Homo sapiens) [TaxId: 9606] [141052] (4) picpic
        SQ Q58EX2 1279-1395! SQ Q58EX2 578-685! SQ Q58EX2 881-988! SQ Q58EX2 981-1081
    38. Neogenin [141053]
      1. Human (Homo sapiens) [TaxId: 9606] [141054] (6) picpic
        SQ Q92859 429-535! SQ Q92859 529-631! SQ Q92859 623-741! SQ Q92859 718-830! SQ Q92859 853-952! SQ Q92859 942-1054
    39. Down syndrome cell adhesion molecule-like protein 1, DSCAML1 [141055]
      1. Human (Homo sapiens) [TaxId: 9606] [141056] (1) picpic
        SQ Q8TD84 979-1087
    40. Myosin binding protein C, fast-type [141057]
      1. Mouse (Mus musculus) [TaxId: 10090] [141058] (1) picpic
        SQ Q5XKE0 731-828
    41. Receptor-type tyrosine-protein phosphatase F, PTPRF [141059]
      1. Human (Homo sapiens) [TaxId: 9606] [141060] (1) picpic
        SQ P10586 811-904
    42. Hedgehog receptor iHog [141061]
      Cg9211-PA
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [141062] (12) picpic
        SQ Q9VM64 466-572! SQ Q9VM64 573-667
    43. Ephrin type-A receptor 1 [141063]
      1. Mouse (Mus musculus) [TaxId: 10090] [141064] (1) picpic
        SQ Q60750 446-539
    44. Insulin receptor [158901]
      1. Human (Homo sapiens) [TaxId: 9606] [158902] (3) picpic
        SQ P06213 495-618
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk