Structural Classification of Proteins
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Family: Interferon regulatory factor

Pfam 00605

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: DNA/RNA-binding 3-helical bundle [46688]
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. Superfamily: "Winged helix" DNA-binding domain [46785]
    contains a small beta-sheet (wing)
    link to SUPERFAMILY database - Superfamily
  5. Family: Interferon regulatory factor [46877]
    Pfam 00605

Protein Domains:

  1. Interferon regulatory factor 1 (IRF-1) [46878]
    1. Mouse (Mus musculus) [TaxId: 10090] [46879] (1)
      1. 1if1 picpic
        protein/DNA complex
        1. chain a [16183] picpiclink
        2. chain b [16184] picpiclink
  2. Interferon regulatory factor-2, IRF-2 [46880]
    1. Mouse (Mus musculus) [TaxId: 10090] [46881] (3)
      1. 2irf picpic
        complexed with ido, k
        1. chain g [16185] picpiclink
        2. chain h [16186] picpiclink
        3. chain i [16187] picpiclink
        4. chain j [16188] picpiclink
        5. chain k [16189] picpiclink
        6. chain l [16190] picpiclink
      2. 1irg picpic
        1. chain a [16191] picpiclink
      3. 1irf picpic
        1. chain a [16192] picpiclink
  3. Interferon regulatory factor 3, IRF-3 [116791]
    1. Human (Homo sapiens) [TaxId: 9606] [116792] (9)
      SQ Q14653 3-112
      1. 2pi0 picpic
        automatically matched to d1t2ka_
        1. region a:5-110 [149489] picpiclink
      2. 2pi0 picpic
        automatically matched to d1t2ka_
        1. region b:3-112 [149490] picpiclink
      3. 2pi0 picpic
        automatically matched to d1t2ka_
        1. region c:4-110 [149491] picpiclink
      4. 2pi0 picpic
        automatically matched to d1t2ka_
        1. region d:3-111 [149492] picpiclink
      5. 2o6g picpic
        automatically matched to d1t2ka_
        1. region e:3-112 [148628] picpiclink
      6. 2o6g picpic
        automatically matched to d1t2ka_
        1. region f:4-111 [148629] picpiclink
      7. 2o6g picpic
        automatically matched to d1t2ka_
        1. region g:3-112 [148630] picpiclink
      8. 2o6g picpic
        automatically matched to d1t2ka_
        1. region h:4-111 [148631] picpiclink
      9. 1t2k picpicxrefxref
        mutant
        1. chain a [112220] picpiclink
        2. chain b [112221] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk