Structural Classification of Proteins
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Family: Tetracyclin repressor-like, N-terminal domain

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: DNA/RNA-binding 3-helical bundle [46688]
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. Superfamily: Homeodomain-like [46689]
    consists only of helices
    link to SUPERFAMILY database - Superfamily
  5. Family: Tetracyclin repressor-like, N-terminal domain [46764]

Protein Domains:

  1. Tetracyclin repressor (Tet-repressor, TetR) [46765]
    1. Escherichia coli [TaxId: 562] [46766] (13)
      1. 2vkv picpicxref
        automatically matched to d1a6ia1
        complexed with mg, tdc; mutant
        1. region a:6-67 [153230] picpiclink
      2. 2vke picpicxref
        automatically matched to d1a6ia1
        complexed with cl, co, tac
        1. region a:2-67 [153221] picpiclink
      3. 2o7o picpicxref
        automatically matched to d1a6i_1
        complexed with cl, dxt, mg, so4; mutant
        1. region a:2-67 [138930] picpiclink
      4. 2fj1 picpicxref
        automatically matched to d1a6i_1
        complexed with cl, ctc, ni; mutant
        1. region a:2-67 [133541] picpiclink
      5. 2tct picpicxref
        complexed with ctc, mg
        1. region a:2-67 [16063] picpiclink
      6. 1bjz picpicxref
        mutant
        1. region a:2-67 [16065] picpiclink
      7. 1a6i picpicxref
        class d variant
        mutant
        1. region a:2-67 [16066] picpiclink
      8. 1ork picpicxref
        class d variant
        complexed with atc, mg; mutant
        1. region a:2-67 [16067] picpiclink
      9. 1du7 picpicxref
        class d; complex with 4-epi-tetracycline
        complexed with ctc; mutant
        1. region a:2-67 [16071] picpiclink
      10. 1bj0 picpicxref
        complexed with ctc; mutant
        1. region a:2-67 [16068] picpiclink
      11. 2trt picpicxref
        complexed with mg, tac
        1. region a:2-67 [16064] picpiclink
      12. 1bjy picpicxref
        complexed with ctc, mg; mutant
        1. region a:2-67 [16069] picpiclink
        2. region b:2-67 [16070] picpiclink
      13. 1qpi picpicxref
        complexed with imd
        1. region a:4-67 [16072] picpiclink
  2. Multidrug binding protein QacR [68964]
    1. Staphylococcus aureus [TaxId: 1280] [68965] (47)
      SQ P23217
      1. 1jt6 picpicxref
        complexed with deq, so4; mutant
        1. region b:2-72 [67249] picpiclink
        2. region d:2-72 [67251] picpiclink
        3. region a:2-72 [67247] picpiclink
        4. region e:2-72 [67253] picpiclink
      2. 1rkw picpicxref
        complexed with pnt, so4; mutant
        1. region a:2-72 [104967] picpiclink
        2. region b:2-72 [104969] picpiclink
        3. region d:2-72 [104971] picpiclink
        4. region e:2-72 [104973] picpiclink
      3. 2hq5 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region a:2-72 [147329] picpiclink
      4. 2hq5 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region b:2-72 [147331] picpiclink
      5. 2hq5 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region d:2-72 [147333] picpiclink
      6. 2hq5 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region e:2-72 [147335] picpiclink
      7. 1jus picpicxref
        complexed with rhq, so4; mutant
        1. region b:2-72 [67328] picpiclink
        2. region d:2-72 [67330] picpiclink
        3. region a:2-72 [67326] picpiclink
        4. region e:2-72 [67332] picpiclink
      8. 2dtz picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region a:2-72 [146578] picpiclink
      9. 3bt9 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region a:2-72 [155550] picpiclink
      10. 3bti picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with ber, so4; mutant
        1. region a:2-72 [155566] picpiclink
      11. 2dtz picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region b:2-72 [146580] picpiclink
      12. 2dtz picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region d:2-72 [146582] picpiclink
      13. 2dtz picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with so4; mutant
        1. region e:2-72 [146584] picpiclink
      14. 3bt9 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region b:2-72 [155552] picpiclink
      15. 3bt9 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region d:2-72 [155554] picpiclink
      16. 3bt9 picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region e:2-72 [155556] picpiclink
      17. 3bti picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with ber, so4; mutant
        1. region b:2-72 [155568] picpiclink
      18. 3bti picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with ber, so4; mutant
        1. region d:2-72 [155570] picpiclink
      19. 3bti picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with ber, so4; mutant
        1. region e:2-72 [155572] picpiclink
      20. 3btl picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region a:2-72 [155582] picpiclink
      21. 3btl picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region b:2-72 [155584] picpiclink
      22. 3btl picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region d:2-72 [155586] picpiclink
      23. 3btl picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region e:2-72 [155588] picpiclink
      24. 1rpw picpicxref
        complexed with did, so4; mutant
        1. region a:2-72 [105036] picpiclink
        2. region b:2-72 [105038] picpiclink
        3. region c:2-72 [105040] picpiclink
        4. region d:2-72 [105042] picpiclink
      25. 3btj picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region a:2-72 [155574] picpiclink
      26. 3btj picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region b:2-72 [155576] picpiclink
      27. 3btj picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region d:2-72 [155578] picpiclink
      28. 3btj picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with deq, so4; mutant
        1. region e:2-72 [155580] picpiclink
      29. 1jtx picpicxref
        complexed with cvi, so4; mutant
        1. region b:2-72 [67286] picpiclink
        2. region d:2-72 [67288] picpiclink
        3. region a:2-72 [67284] picpiclink
        4. region e:2-72 [67290] picpiclink
      30. 2g0e picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with cgq, so4
        1. region a:2-72 [147058] picpiclink
      31. 2g0e picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with cgq, so4
        1. region b:2-72 [147060] picpiclink
      32. 2g0e picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with cgq, so4
        1. region d:2-72 [147062] picpiclink
      33. 2g0e picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with cgq, so4
        1. region e:2-72 [147064] picpiclink
      34. 1qvt picpicxref
        complexed with pf, so4
        1. region a:2-72 [104602] picpiclink
        2. region b:2-72 [104604] picpiclink
        3. region d:2-72 [104606] picpiclink
        4. region e:2-72 [104608] picpiclink
      35. 2gby picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with brn, so4
        1. region a:2-72 [147102] picpiclink
      36. 2gby picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with brn, so4
        1. region b:2-72 [147104] picpiclink
      37. 2gby picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with brn, so4
        1. region d:2-72 [147106] picpiclink
      38. 2gby picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with brn, so4
        1. region e:2-72 [147108] picpiclink
      39. 3btc picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region a:2-72 [155558] picpiclink
      40. 3btc picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region b:2-72 [155560] picpiclink
      41. 3btc picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region d:2-72 [155562] picpiclink
      42. 3btc picpicxrefxrefxrefxref
        automatically matched to d1jt0a1
        complexed with mgr, so4; mutant
        1. region e:2-72 [155564] picpiclink
      43. 1qvu picpicxref
        complexed with et, pf
        1. region a:2-72 [104610] picpiclink
        2. region b:2-72 [104612] picpiclink
        3. region d:2-72 [104614] picpiclink
        4. region e:2-72 [104616] picpiclink
      44. 1jt0 picpicxref
        complexed with so4; mutant
        1. region a:2-72 [71850] picpiclink
        2. region b:2-72 [71852] picpiclink
        3. region c:2-72 [71854] picpiclink
        4. region d:2-72 [71856] picpiclink
      45. 1jum picpicxref
        complexed with ber, so4; mutant
        1. region b:2-72 [67306] picpiclink
        2. region d:2-72 [67308] picpiclink
        3. region a:2-72 [67304] picpiclink
        4. region e:2-72 [67310] picpiclink
      46. 1jup picpicxref
        complexed with mgr, so4; mutant
        1. region b:2-72 [67316] picpiclink
        2. region d:2-72 [67318] picpiclink
        3. region a:2-72 [67314] picpiclink
        4. region e:2-72 [67320] picpiclink
      47. 1jty picpicxref
        complexed with et, so4; mutant
        1. region b:2-72 [67294] picpiclink
        2. region d:2-72 [67296] picpiclink
        3. region a:2-72 [67292] picpiclink
        4. region e:2-72 [67298] picpiclink
  3. Hypothetical transcriptional regulator YcdC [88973]
    1. Escherichia coli [TaxId: 562] [88974] (1)
      1. 1pb6 picpicxref
        1. region a:14-85 [88017] picpiclink
        2. region b:14-85 [88019] picpiclink
        3. region c:14-85 [88021] picpiclink
        4. region d:14-85 [88023] picpiclink
  4. Hypothetical transcriptional regulator YsiA [101003]
    1. Bacillus subtilis [TaxId: 1423] [101004] (1)
      1. 1vi0 picpicxref
        structural genomics
        complexed with dcc
        1. region a:6-77 [100720] picpiclink
        2. region b:6-77 [100722] picpiclink
  5. Hypothetical transcriptional regulator YfiR [101005]
    1. Bacillus subtilis [TaxId: 1423] [101006] (1)
      1. 1rkt picpicxref
        structural genomics
        complexed with unx
        1. region a:2-82 [97623] picpiclink
        2. region b:6-82 [97625] picpiclink
  6. Ethr repressor [109651]
    1. Mycobacterium tuberculosis [TaxId: 1773] [109652] (3)
      SQ P96222 22-215
      1. 1t56 picpicxref
        complexed with dox, gol
        1. region a:22-94 [106428] picpiclink
      2. 1u9n picpicxref
        complexed with cns
        1. region a:22-94 [113246] picpiclink
      3. 1u9o picpicxref
        complexed with cns
        1. region a:22-94 [113248] picpiclink
  7. A-factor receptor homolog CprB [109653]
    gamma-butyrolactone receptor
    1. Streptomyces coelicolor [TaxId: 1902] [109654] (2)
      SQ O66122
      1. 1ui5 picpicxref
        1. region a:5-75 [107856] picpiclink
        2. region b:5-75 [107858] picpiclink
      2. 1ui6 picpicxref
        1. region a:5-75 [107860] picpiclink
        2. region b:6-75 [107862] picpiclink
  8. Putative transcriptional repressor YbiH [109655]
    1. Salmonella typhimurium [TaxId: 90371] [109656] (1)
      SQ Q8ZQN9
      1. 1t33 picpicxref
        Structural genomics target
        1. region a:1-88 [106295] picpiclink
        2. region b:7-88 [106297] picpiclink
  9. Putative transcriptional regulator YxaF [109657]
    1. Bacillus subtilis [TaxId: 1423] [109658] (1)
      SQ P42105
      1. 1sgm picpicxref
        1. region a:5-77 [105537] picpiclink
        2. region b:5-77 [105539] picpiclink
  10. Transcriptional regulator BC3163 [140175]
    1. Bacillus cereus [TaxId: 1396] [140176] (1)
      SQ Q81BJ4 9-77
      1. 2fq4 picpicxref
        1. region a:9-77 [133937] picpiclink
  11. Putative transcriptional regulator [140177]
    1. Rhodococcus sp. rha1 [TaxId: 101510] [140178] (2)
      1. 2g3b picpicxrefxref
        complexed with gol
        1. region a:2-73 [134558] picpiclink
      2. 2g3b picpicxrefxref
        automatically matched to 2G3B A:2-73
        complexed with gol
        1. region b:2-73 [134560] picpiclink
  12. Putative transcriptional regulator SCO5951 [140179]
    1. Streptomyces coelicolor [TaxId: 1902] [140180] (2)
      SQ O54180 13-80
      1. 2id3 picpicxrefxref
        complexed with ca, cl
        1. region a:13-80 [137261] picpiclink
      2. 2id3 picpicxrefxref
        automatically matched to 2ID3 A:13-80
        complexed with ca, cl
        1. region b:14-80 [137263] picpiclink
  13. Transcriptional regulator Cgl2612 [140181]
    1. Corynebacterium glutamicum [TaxId: 1718] [140182] (4)
      SQ Q8NMG3 1-174
      1. 1v7b picpicxrefxref
        1. region a:1-74 [119861] picpiclink
      2. 1v7b picpicxrefxref
        automatically matched to 1V7B A:1-74
        1. region b:3-74 [119863] picpiclink
      3. 2zoz picpicxrefxref
        complexed with et, gol, so4
        1. region a:3-73 [154740] picpiclink
      4. 2zoz picpicxrefxref
        automatically matched to 2ZOZ A:3-73
        complexed with et, gol, so4
        1. region b:3-73 [154742] picpiclink
  14. Transcriptional regulator EF0787 [140183]
    1. Enterococcus faecalis [TaxId: 1351] [140184] (2)
      SQ Q837P6 4-71
      1. 1z0x picpicxrefxref
        complexed with cl
        1. region a:4-71 [124334] picpiclink
      2. 1z0x picpicxrefxref
        automatically matched to 1Z0X A:4-71
        complexed with cl
        1. region b:4-71 [124336] picpiclink
  15. Putative transcriptional regulator RHA1_ro09068 [140185]
    1. Rhodococcus sp. [TaxId: 1831] [140186] (2)
      SQ Q0RX74 10-78
      1. 2i10 picpicxrefxref
        complexed with npo, pge
        1. region a:10-78 [136960] picpiclink
      2. 2i10 picpicxrefxref
        automatically matched to 2I10 A:10-78
        complexed with npo, pge
        1. region b:11-78 [136962] picpiclink
  16. Probable transcriptional regulator PA3133 [140187]
    1. Pseudomonas aeruginosa [TaxId: 287] [140188] (1)
      SQ Q9HZ91 1-76
      1. 2fd5 picpicxref
        1. region a:1-76 [133291] picpiclink
  17. Transcriptional regulator RHA1_ro04179 [140189]
    1. Rhodococcus sp. [TaxId: 1831] [140190] (4)
      SQ Q0S914 9-77
      1. 2np5 picpicxrefxrefxrefxref
        complexed with lmt, nds
        1. region a:9-77 [138424] picpiclink
      2. 2np5 picpicxrefxrefxrefxref
        automatically matched to 2NP5 A:9-77
        complexed with lmt, nds
        1. region b:9-77 [138426] picpiclink
      3. 2np5 picpicxrefxrefxrefxref
        automatically matched to 2NP5 A:9-77
        complexed with lmt, nds
        1. region c:10-77 [138428] picpiclink
      4. 2np5 picpicxrefxrefxrefxref
        automatically matched to 2NP5 A:9-77
        complexed with lmt, nds
        1. region d:10-77 [138430] picpiclink
  18. Transcriptional regulator BC5000 [140191]
    1. Bacillus cereus [TaxId: 1396] [140192] (2)
      SQ Q815X4 6-77
      1. 1zk8 picpicxrefxref
        1. region a:6-77 [125177] picpiclink
      2. 1zk8 picpicxrefxref
        automatically matched to 1ZK8 A:6-77
        1. region b:8-77 [125179] picpiclink
  19. Probable transcriptional regulator RHA1_ro04631 [140193]
    1. Rhodococcus sp. rha1 [TaxId: 101510] [140194] (2)
      SQ Q0S7R9 4-80
      1. 2gfn picpicxrefxref
        complexed with cl
        1. region a:4-80 [135101] picpiclink
      2. 2gfn picpicxrefxref
        automatically matched to 2GFN A:4-80
        complexed with cl
        1. region b:7-80 [135103] picpiclink
  20. Putative transcriptional regulator Rha04620 [140195]
    1. Rhodococcus sp. rha1 [TaxId: 101510] [140196] (1)
      1. 2g7g picpicxref
        complexed with acy
        1. region a:9-73 [134732] picpiclink
  21. Hemolysin II regulatory protein, HlyIIR [140197]
    1. Bacillus cereus [TaxId: 1396] [140198] (1)
      SQ Q7X506 4-76
      1. 2fx0 picpicxref
        1. region a:4-76 [134269] picpiclink
  22. Putative transcriptional regulator SCO7704 [140199]
    1. Streptomyces coelicolor [TaxId: 1902] [140200] (1)
      SQ Q93JG8 16-83
      1. 2g7l picpicxref
        1. region a:16-83 [134734] picpiclink
  23. Probable transcriptional regulator PA1836 [140201]
    1. Pseudomonas aeruginosa [TaxId: 287] [140202] (1)
      SQ Q9I2Q9 6-75
      1. 2gen picpicxref
        1. region a:6-75 [135062] picpiclink
  24. Putative regulator SCO4008 [140203]
    1. Streptomyces coelicolor [TaxId: 1902] [140204] (2)
      SQ Q9ADP7 7-74
      1. 2d6y picpicxrefxref
        complexed with tla
        1. region a:7-74 [131313] picpiclink
      2. 2d6y picpicxrefxref
        automatically matched to 2D6Y A:7-74
        complexed with tla
        1. region b:7-74 [131315] picpiclink
  25. Transcriptional regulator PsrA [140205]
    1. Pseudomonas aeruginosa [TaxId: 287] [140206] (1)
      SQ Q9HZJ9 2-80
      1. 2fbq picpicxref
        1. region a:2-80 [133256] picpiclink
  26. Putative transcriptional regulator SCO0857 [140207]
    1. Streptomyces coelicolor [TaxId: 1902] [140208] (2)
      SQ Q9RCV4 35-99
      1. 2np3 picpicxrefxref
        1. region a:35-99 [138420] picpiclink
      2. 2np3 picpicxrefxref
        automatically matched to 2NP3 A:35-99
        1. region b:35-99 [138422] picpiclink
  27. Transcriptional regulator TM1030 [140209]
    1. Thermotoga maritima [TaxId: 2336] [140210] (5)
      SQ Q9X0C0 1-75! SQ Q9X0C0 2-75
      1. 2id6 picpicxref
        automatically matched to d1z77a1
        complexed with edo
        1. region a:1-75 [147624] picpiclink
      2. 2iek picpicxref
        automatically matched to d1z77a1
        complexed with p2k
        1. region a:2-75 [147647] picpiclink
      3. 1z77 picpicxref
        complexed with edo
        1. region a:1-75 [124588] picpiclink
      4. 1zkg picpicxrefxref
        complexed with unl
        1. region a:2-75 [125194] picpiclink
      5. 1zkg picpicxrefxref
        automatically matched to 1ZKG A:2-75
        complexed with unl
        1. region b:2-75 [125196] picpiclink
  28. Putative transcriptional regulator Atu0279 [140211]
    1. Agrobacterium tumefaciens [TaxId: 358] [140212] (1)
      SQ Q8UIL4 3-76
      1. 2g7s picpicxref
        1. region a:3-76 [134737] picpiclink
  29. Transcriptional activator DhaS [158248]
    1. Lactococcus lactis [TaxId: 1358] [158249] (2)
      SQ Q9CIV9 8-78
      1. 2iu5 picpicxrefxref
        mutant
        1. region a:1-71 [147801] picpiclink
      2. 2iu5 picpicxrefxref
        automatically matched to 2IU5 A:1-71
        mutant
        1. region b:4-71 [147803] picpiclink
  30. Putative transcriptional regulator SCO4940 [158250]
    1. Streptomyces coelicolor [TaxId: 1902] [158251] (1)
      SQ Q8CJS4 8-82
      1. 2hyj picpicxref
        complexed with ca, so4
        1. region a:8-82 [147456] picpiclink
  31. Putative transcriptional regulator RHA1_ro03468 [158252]
    1. Rhodococcus sp. RHA1 [TaxId: 101510] [158253] (2)
      SQ Q0SB15 18-87
      1. 2hku picpicxrefxref
        complexed with edo, pg4
        1. region a:18-87 [147302] picpiclink
      2. 2hku picpicxrefxref
        automatically matched to 2HKU A:18-87
        complexed with edo, pg4
        1. region b:19-87 [147304] picpiclink
  32. Putative regulatory protein Sco4313 [158254]
    1. Streptomyces coelicolor [TaxId: 1902] [158255] (1)
      SQ Q9KXS8 8-86
      1. 2oi8 picpicxref
        1. region a:8-86 [148778] picpiclink
  33. Transcriptional regulator Cgl1640/Cg1846 [158256]
    1. Corynebacterium glutamicum [TaxId: 1718] [158257] (1)
      SQ Q8NQ14 1-78
      1. 2o7t picpicxref
        complexed with unl
        1. region a:1-78 [148670] picpiclink
  34. Putative transcriptional regulator SCO4850 [158258]
    1. Streptomyces coelicolor [TaxId: 1902] [158259] (1)
      SQ Q9KZ96 15-89
      1. 3c07 picpicxref
        complexed with so4
        1. region a:15-89 [155807] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk