Structural Classification of Proteins
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Fold: HLH-like

4-helices; bundle, closed, left-handed twist; 2 crossover connections

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: HLH-like [47458]
    4-helices; bundle, closed, left-handed twist; 2 crossover connections

Superfamilies:

  1. HLH, helix-loop-helix DNA-binding domain [47459] (1)
    dimer of two identical helix-loop-helix subunits
    link to SUPERFAMILY database - Superfamily
    1. HLH, helix-loop-helix DNA-binding domain [47460] (9)
      1. Max protein [47461]
        BHLHZ region; contains leucine-zipper motif
        1. Human (Homo sapiens) [TaxId: 9606] [47462] (4)
          1. 1nkp picpicxref
            complexed with Myc
            1. chain b [80574] picpiclink
            2. chain e [80576] picpiclink
          2. 1nlw picpicxref
            complexed with Mad
            1. chain b [80634] picpiclink
            2. chain e [80636] picpiclink
          3. 1hlo picpic
            protein/DNA complex
            1. chain a [17128] picpiclink
            2. chain b [17129] picpiclink
          4. 1r05 picpic
            mutant
            1. chain a [96723] picpiclink
            2. chain b [96724] picpiclink
        2. Mouse (Mus musculus) [TaxId: 10090] [47463] (1)
          1. 1an2 picpic
            protein/DNA complex
            1. chain a [17130] picpiclink
      2. Myc proto-oncogene protein [81750]
        1. Human (Homo sapiens) [TaxId: 9606] [81751] (1)
          BHLHZ region; contains leucine-zipper motif
          1. 1nkp picpicxref
            complexed with Max
            1. chain a [80573] picpiclink
            2. chain d [80575] picpiclink
      3. Mad protein [81752]
        1. Human (Homo sapiens) [TaxId: 9606] [81753] (1)
          BHLHZ region; contains leucine-zipper motif
          1. 1nlw picpicxref
            complexed with Max
            1. chain a [80633] picpiclink
            2. chain d [80635] picpiclink
      4. Myod B/HLH domain [47464]
        1. Mouse (Mus musculus) [TaxId: 10090] [47465] (1)
          1. 1mdy picpic
            protein/DNA complex; mutant
            1. chain a [17132] picpiclink
            2. chain b [17133] picpiclink
            3. chain c [17134] picpiclink
            4. chain d [17135] picpiclink
      5. Usf B/HLH domain [47466]
        1. Human (Homo sapiens) [TaxId: 9606] [47467] (1)
          1. 1an4 picpic
            protein/DNA complex; mutant
            1. chain a [17136] picpiclink
            2. chain b [17137] picpiclink
      6. Pho4 B/HLH domain [47468]
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [47469] (1)
          1. 1a0a picpic
            protein/DNA complex
            1. chain a [17138] picpiclink
            2. chain b [17139] picpiclink
      7. SREBP-1a [47470]
        1. Human (Homo sapiens) [TaxId: 9606] [47471] (1)
          1. 1am9 picpic
            protein/DNA complex; complexed with mo6; mutant
            1. chain a [17140] picpiclink
            2. chain b [17141] picpiclink
            3. chain c [17142] picpiclink
            4. chain d [17143] picpiclink
      8. SREBP-2 [101171]
        1. Human (Homo sapiens) [TaxId: 9606] [101172] (1)
          1. 1ukl picpicxref
            complexed with importin-beta
            1. chain c [99495] picpiclink
            2. chain d [99496] picpiclink
            3. chain e [99497] picpiclink
            4. chain f [99498] picpiclink
  2. Docking domain B of the erythromycin polyketide synthase (DEBS) [101173] (1)
    link to SUPERFAMILY database - Superfamily
    1. Docking domain B of the erythromycin polyketide synthase (DEBS) [101174] (1)
      1. Erythronolide synthase [101175]
        1. Saccharopolyspora erythraea [TaxId: 1836] [101176] (1)
          1. 1pzr picpic
            fused interacting segments
            1. chain a [95468] picpiclink
            2. chain b [95469] picpiclink

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk