Structural Classification of Proteins

Family: Phage repressors

: consists of different sequence families of HTH repressors of phage origins

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: lambda repressor-like DNA-binding domains [47412]
core: 4 helices; folded leaf, closed
Superfamily: lambda repressor-like DNA-binding domains [47413]
uperfamily
Family: Phage repressors [47419]
consists of different sequence families of HTH repressors of phage origins

Protein Domains:

lambda C1 repressor, DNA-binding domain [47420]
1. Bacteriophage lambda [TaxId: 10710] [47421] (6)
  1. 1lmb
    protein/DNA complex
    1. chain 3 [17023]
    2. chain 4 [17024]
  2. 1lli
    protein/DNA complex; mutant
    1. chain a [17025]
    2. chain b [17026]
  3. 1rio
    complexed with ca, mpd
    1. chain a [97513]
    2. chain b [97514]
  4. 1lrp
    CA-atoms only
    1. chain a [17027]
  5. 1lrp
    duplicate of 1LRP
    1. chain b [118551]
  6. 1lrp
    duplicate of 1LRP
    1. chain c [118552]
434 C1 repressor, DNA-binding domain [47422]
1. Bacteriophage 434 [TaxId: 10712] [47423] (8)
  SQ P16117 10-62; contains a short additional helix at C-terminus
  1. 1r69
    1. chain a [17028]
  2. 1per
    protein/DNA complex
    1. chain l [17029]
    2. chain r [17030]
  3. 2or1
    protein/DNA complex
    1. chain l [17031]
    2. chain r [17032]
  4. 1rpe
    protein/DNA complex
    1. chain l [17033]
    2. chain r [17034]
  5. 1r63
    1. chain a [17035]
  6. 1pra
    1. chain a [17037]
  7. 2r63
    mutant
    1. chain a [17036]
  8. 1sq8
    design mutant devoid of hydroxyl groups
    1. chain a [105888]
cro 434 [47424]
1. Bacteriophage 434 [TaxId: 10712] [47425] (3)
  contains a short additional helix at C-terminus
  1. 2cro
    1. chain a [17038]
  2. 3cro
    protein/DNA complex
    1. chain l [17039]
    2. chain r [17040]
  3. 1zug
    1. chain a [17041]
P22 C2 repressor, DNA-binding domain [47426]
1. Salmonella bacteriophage P22 [TaxId: 10754] [47427] (3)
  contains a short additional helix at C-terminus
  1. 2r1j
    automatically matched to d1adra_
    1. region l:3-68 [151525]
  2. 2r1j
    automatically matched to d1adra_
    1. region r:3-68 [151526]
  3. 1adr
    1. chain a [17042]
cro lambda repressor [47428]
the fourth helix is replaced with a beta hairpin
3 helices; folded leaf, opened
1. Bacteriophage lambda [TaxId: 10710] [47429] (9)
  1. 1d1l
    complexed with so4; mutant
    1. chain a [17057]
  2. 5cro
    complexed with po4
    1. chain o [17043]
    2. chain a [17044]
    3. chain b [17045]
    4. chain c [17046]
  3. 6cro
    protein/DNA complex; complexed with so4
    1. chain a [17047]
  4. 3orc
    engineered cro monomer bound nonspecifically to DNA
    protein/DNA complex; mutant
    1. chain a [17061]
  5. 4cro
    CA-atoms only
    protein/DNA complex
    1. chain a [17048]
    2. chain b [17049]
    3. chain c [17050]
    4. chain d [17051]
    5. chain e [17052]
    6. chain f [17053]
  6. 1cop
    1. chain d [17058]
    2. chain e [17059]
  7. 1orc
    monomeric insertion mutant
    1. chain a [17054]
  8. 1d1m
    insertion mutant k56-[dgevk]-f58w
    1. chain b [17055]
    2. chain a [17056]
  9. 2orc
    insertion mutant k56-[dgevk]
    1. chain a [17060]
Ner [47430]
1. Bacteriophage mu [TaxId: 10677] [47431] (2)
  1. 1ner
    1. chain a [17062]
  2. 1neq
    1. chain a [17063]
cro p22 [109809]
1. Bacteriophage p22 [TaxId: 10754] [109810] (1)
  SQ P09964
  1. 1rzs
    1. chain a [105139]