Structural Classification of Proteins
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Fold: Ferritin-like

core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Ferritin-like [47239]
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection

Superfamilies:

  1. Ferritin-like [47240] (9)
    contains bimetal-ion centre in the middle of the bundle
    link to SUPERFAMILY database - Superfamily
    1. Ferritin [47241] (34) picpic
    2. Ribonucleotide reductase-like [47253] (18) picpic
    3. Manganese catalase (T-catalase) [100951] (2) picpic
    4. YciF-like [140445] (2) picpic
      Pfam 05974; DUF892
    5. half-ferritin [140450] (1) picpic
      comprise of alpha-hairpin subunits forming the ferritin-like four-helical bundle; assembles further in a homodecamer
    6. PMT1231-like [158402] (1) picpic
      PfamB 016165
    7. MiaE-like [158405] (1) picpic
      Pfam 06175; tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)
    8. AMB4284-like [158408] (1) picpic
      possible rubrerythrin
    9. Rv2844-like [158411] (1) picpic
      PfamB 061364
  2. Cobalamin adenosyltransferase-like [89028] (2)
    crossover loop goes across a different side of the 4-helical bundle; no internal metal-binding site
    link to SUPERFAMILY database - Superfamily
    1. Cobalamin adenosyltransferase [89032] (2) picpic
    2. Hypothetical protein Ta1238 [89029] (1) picpic
  3. EsxAB dimer-like [140453] (1)
    (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals
    link to SUPERFAMILY database - Superfamily
    1. ESAT-6 like [140454] (2) picpic
      Pfam 06013; the conserwed WxG motif makes the turn at the alpha-hairpin tip
  4. PE/PPE dimer-like [140459] (2)
    (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals inside the bundle
    link to SUPERFAMILY database - Superfamily
    1. PE [140460] (1) picpic
      Pfam 00934; pairs with with the N-terminal hairpin of PPE
    2. PPE [140463] (1) picpic
      Pfam 00823; contains extra C-terminal alpha-hairpin, unlike the PE family subunit
  5. HP0062-like [158414] (1)
    (homo)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals
    1. HP0062-like [158415] (1) picpic
      Pfam 09647
  6. SO2669-like [158418] (1)
    (homo)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals
    1. SO2669-like [158419] (1) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk