Structural Classification of Proteins

Superfamily: Multiheme cytochromes

: duplication: contains multiple CxxCH motifs
uperfamily

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: Multiheme cytochromes [48694]
variable number of helices and little beta structure; not a true fold
Superfamily: Multiheme cytochromes [48695]
duplication: contains multiple CxxCH motifs
uperfamily

Families:

Cytochrome c3-like [48696] (13)
1. Cytochrome c3 [48697]
  contains four heme groups
  1. Desulfovibrio desulfuricans, different strains [TaxId: 876] [48698] (8)
    SQ Q9L915
    1. 1up9
      complexed with hec, so4
      1. chain a [113390]
    2. 1upd
      complexed with hec
      1. chain a [113391]
    3. 3cyr
      complexed with hem
      1. chain a [19648]
    4. 1i77
      complexed with hem
      1. chain a [61878]
    5. 1gmb
      complexed with hec, so4
      1. chain a [76233]
    6. 2cy3
      complexed with hem
      1. chain a [19649]
    7. 1gm4
      complexed with hec, so4
      1. chain a [76232]
    8. 1aqe
      complexed with hem, so4; mutant
      1. chain a [19650]
  2. Desulfovibrio vulgaris [TaxId: 881] [48699] (11)
    SQ P00132
    1. 1j0p
      complexed with eoh, hem, so4; mutant
      1. chain a [90743]
    2. 1j0o
      complexed with eoh, hem
      1. chain a [90742]
    3. 1wr5
      complexed with eoh, hem; mutant
      1. chain a [114835]
    4. 2cth
      complexed with hem
      1. chain a [19652]
      2. chain b [19653]
    5. 2ffn
      automatically matched to d1it1a_
      complexed with hem; mutant
      1. region a:1-107 [133390]
    6. 2cdv
      complexed with hem
      1. chain a [19651]
    7. 2cym
      complexed with hem
      1. chain a [19654]
    8. 1mdv
      complexed with hem; mutant
      1. chain a [19655]
      2. chain b [19656]
    9. 1a2i
      complexed with hec
      1. chain a [19657]
    10. 2bpn
      automatically matched to d1a2i__
      complexed with hec
      1. region a:1-107 [128950]
    11. 1it1
      complexed with hec
      1. chain a [71406]
  3. Desulfovibrio gigas [TaxId: 879] [48700] (3)
    1. 1wad
      complexed with ca, hem
      1. chain a [19658]
    2. 1qn0
      complexed with hec
      1. chain a [19659]
    3. 1qn1
      complexed with hec
      1. chain a [19660]
  4. Desulfovibrio gigas, di-tetraheme cytochrome c3 [TaxId: 879] [74804] (1)
    disulfide-crosslinked dimer
    1. 1gyo
      complexed with gol, hec
      1. chain a [70763]
      2. chain b [70764]
  5. Desulfovibrio africanus [TaxId: 873] [48701] (2)
    1. 3cao
      complexed with ars, cgn, hem, zn
      1. chain a [19661]
    2. 3car
      complexed with ars, cgn, hem, zn
      1. chain a [19662]
  6. Desulfomicrobium norvegicum [TaxId: 52561] [48702] (1)
    synonym: Desulfovibrio desulfuricans Norway
    1. 1czj
      complexed with hem, so4
      1. chain a [19663]
  7. Desulfovibrio baculatus (Desulfomicrobium baculatus) [TaxId: 899] [117036] (1)
    SQ Q6XCI5 # fragment
    1. 1w7o
      complexed with hec
      1. chain a [114318]
2. Cytochrome c7 (cytochrome c551.5, PpcA) [48703]
  contains three heme groups; deletion of one of Cyt c3 heme-binding sites
  1. Desulfuromonas acetoxidans [TaxId: 891] [48704] (8)
    1. 1hh5
      complexed with hec
      1. chain a [61041]
    2. 1l3o
      complexed with hec; mutant
      1. chain a [73551]
    3. 1kwj
      complexed with hec; mutant
      1. chain a [68877]
    4. 1new
      complexed with hec
      1. chain a [19664]
    5. 2new
      complexed with hec
      1. chain a [19666]
    6. 1f22
      complexed with hec
      1. chain a [19665]
    7. 1ehj
      complexed with hec
      1. chain a [19667]
    8. 1lm2
      complexed with cr, hec
      1. chain a [74026]
  2. Geobacter sulfurreducens, PpcA [TaxId: 35554] [101502] (1)
    1. 1os6
      complexed with dxc, hem, so4
      1. chain a [93476]
  3. Geobacter sulfurreducens, GSU1996 [TaxId: 35554] [110039] (1)
    SQ Q74BP5
    1. 1rwj
      complexed with hem
      1. chain a [105114]
3. Nine-heme cytochrome c [48705]
  tandem repeat of two cytochrome c3-like domains with additional heme-binding site in the domain interface
  1. Desulfovibrio desulfuricans, ATCC 27774 [TaxId: 876] [48706] (3)
    1. 1ofw
      complexed with act, gol, hec
      1. chain a [92850]
      2. chain b [92851]
    2. 19hc
      1. chain a [19668]
      2. chain b [19669]
    3. 1ofy
      complexed with act, gol, hec
      1. chain a [92852]
      2. chain b [92853]
  2. Desulfovibrio desulfuricans, ATCC 29577 [TaxId: 876] [63634] (1)
    1. 1duw
      complexed with gol, hem
      1. chain a [59138]
4. 16-heme cytochrome c HmcA [81940]
  tandem repeat of four cytochrome c3-like domains
  1. Desulfovibrio vulgaris [TaxId: 881] [81941] (3)
    1. 2cvc
      automatically matched to d1h29c_
      complexed with hem
      1. region a:40-544 [130860]
    2. 1h29
      complexed with hec
      1. chain a [76546]
      2. chain b [76547]
      3. chain c [76548]
      4. chain d [76549]
    3. 1gws
      complexed with hec, hem
      1. chain a [76370]
Photosynthetic reaction centre (cytochrome subunit) [48707] (2)
consists of four heme-binding repeats
1. Photosynthetic reaction centre (cytochrome subunit) [48708]
  1. Rhodopseudomonas viridis [TaxId: 1079] [48709] (11)
    1. 2i5n
      automatically matched to d1prcc_
      complexed with bcb, bpb, fe2, hec, hto, lda, mq9, ns5, so4, unl, uq1
      1. region c:1-332 [137063]
    2. 1dxr
      complexed with bcb, bpb, fe2, hec, lda, mq9, mst, ns5, so4; mutant
      1. chain c [19670]
    3. 6prc
      complexed with 7mq, bcb, bpb, ceb, fe2, hem, lda, ns5, so4
      1. chain c [19671]
    4. 3prc
      complexed with 7mq, bcb, bpb, fe2, hem, lda, ns5, so4
      1. chain c [19672]
    5. 5prc
      complexed with 7mq, atz, bcb, bpb, fe2, hem, lda, ns5, so4
      1. chain c [19673]
    6. 4prc
      complexed with 7mq, bcb, bpb, fe2, hem, lda, ns5, sma, so4
      1. chain c [19676]
    7. 2prc
      complexed with 7mq, bcb, bpb, fe2, hem, lda, ns5, so4, uq2
      1. chain c [19675]
    8. 1prc
      complexed with bcl, bpb, fe, hem, lda, mq7, ns1, so4, uq1
      1. chain c [19674]
    9. 7prc
      complexed with 7mq, bcb, bpb, cet, fe2, hem, lda, ns5, so4
      1. chain c [19677]
    10. 1r2c
      complexed with 7mq, bcb, bpb, fe2, hem, lda, ns5, so4, uq2
      1. chain c [96859]
    11. 3d38
      automatically matched to d1prcc_
      complexed with bcb, bpb, fe2, hec, hto, lda, mq9, ns5, so4, uq1
      1. region c:1-332 [157273]
  2. Thermochromatium tepidum [TaxId: 1050] [48710] (1)
    1. 1eys
      complexed with bcl, bgl, bph, crt, fe, hem, lda, mq8, pef
      1. chain c [19678]
Di-heme elbow motif [48711] (13)
the main characteristic feature of this motif is the packing of its two hemes
many members contains one or more complete motifs flanked by incomplete motifs and/or other domains
1. Periplasmic nitrate reductase subunit NapB [74805]
  1. Haemophilus influenzae [TaxId: 727] [74806] (1)
    1. 1jni
      complexed with hem
      1. chain a [71761]
  2. Rhodobacter sphaeroides [TaxId: 1063] [101503] (1)
    1. 1ogy
      complexed with hec, mgd, mo, sf4
      1. chain b [92954]
      2. chain d [92957]
      3. chain f [92960]
      4. chain h [92963]
      5. chain j [92966]
      6. chain l [92969]
      7. chain n [92972]
      8. chain p [92975]
2. Hydroxylamine oxidoreductase, HAO [48712]
  contains 3 complete motifs
  1. Nitrosomonas europaea [TaxId: 915] [48713] (1)
    1. 1fgj
      complexed with hec, hem
      1. chain a [19679]
      2. chain b [19680]
3. Cytochrome c554 [48714]
  contains 1 complete motif
  1. Nitrosomonas europaea [TaxId: 915] [48715] (3)
    1. 1ft5
      complexed with hem, ips
      1. chain a [19681]
    2. 1ft6
      complexed with dtn, hem, ips, so3
      1. chain a [19682]
    3. 1bvb
      CASP3
      complexed with hem, po4
      1. chain a [19683]
4. Dimeric di-heme split-soret cytochrome c [48716]
  1. Desulfovibrio desulfuricans, ATCC 27774 [TaxId: 876] [48717] (1)
    1. 1h21
      complexed with hec
      1. chain a [76510]
      2. chain b [76511]
      3. chain c [76512]
      4. chain d [76513]
5. Cytochrome c nitrite reductase [48718]
  1. Sulfurospirillum deleyianum [TaxId: 65553] [48719] (1)
    1. 1qdb
      complexed with ca, hem, so4
      1. chain a [19688]
      2. chain b [19689]
      3. chain c [19690]
  2. Wolinella succinogenes [TaxId: 844] [48720] (6)
    1. 1fs7
      complexed with act, ca, hem, y1
      1. chain a [19691]
    2. 2e80
      automatically matched to d1fs7a_
      complexed with act, ca, hem, no2, yt3
      1. region a:37-507 [132092]
    3. 1fs8
      complexed with act, ca, hem, so4, y1
      1. chain a [19692]
    4. 1fs9
      complexed with azi, ca, hem, y1
      1. chain a [19693]
    5. 3bnf
      automatically matched to d1fs7a_
      complexed with act, ca, hem, so3, y1
      1. region a:37-507 [155438]
    6. 2e81
      automatically matched to d1fs7a_
      complexed with ca, hem, hoa, yt3
      1. region a:37-507 [132093]
  3. Escherichia coli [TaxId: 562] [74807] (5)
    1. 2rdz
      automatically matched to d1gu6a_
      complexed with ca, edo, hec, so4
      1. region a:38-477 [151967]
    2. 2rdz
      automatically matched to d1gu6a_
      complexed with ca, edo, hec, so4
      1. region b:38-477 [151968]
    3. 2rdz
      automatically matched to d1gu6a_
      complexed with ca, edo, hec, so4
      1. region c:38-477 [151969]
    4. 2rdz
      automatically matched to d1gu6a_
      complexed with ca, edo, hec, so4
      1. region d:38-477 [151970]
    5. 1gu6
      complexed with ca, gol, hec
      1. chain a [70575]
      2. chain c [70576]
      3. chain e [70577]
      4. chain g [70578]
  4. Desulfovibrio desulfuricans [TaxId: 876] [89173] (1)
    1. 1oah
      complexed with ca, cl, hem, zn
      1. chain a [86736]
      2. chain b [86737]
6. Flavocytochrome c3 (respiratory fumarate reductase), N-terminal domain [48721]
  1. Shewanella frigidimarina [TaxId: 56812] [48722] (16)
    1. 1y0p
      automatically matched to d1e39a1
      complexed with fad, hem, mez, na
      1. region a:1-102 [122507]
    2. 1q9i
      complexed with fad, hem, na, teo; mutant
      1. region a:1-102 [96273]
    3. 2b7r
      automatically matched to d1e39a1
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [128049]
    4. 1kss
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [72928]
    5. 1m64
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [78683]
      2. region b:1-102 [78686]
    6. 1e39
      complexed with fad, fum, gol, hec, na; mutant
      1. region a:1-102 [19694]
    7. 1ksu
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [72931]
      2. region b:1-102 [72934]
    8. 2b7s
      automatically matched to d1e39a1
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [128052]
    9. 1qjd
      1. region a:1-102 [19695]
    10. 1jry
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [67199]
      2. region b:1-102 [67202]
    11. 1lj1
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [78023]
      2. region b:1-102 [78026]
    12. 1jrz
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [67205]
      2. region b:1-102 [67208]
    13. 1jrx
      complexed with fad, fum, hem, na; mutant
      1. region a:1-102 [67193]
      2. region b:1-102 [67196]
    14. 1p2e
      complexed with acy, fad, fum, hem, na; mutant
      1. region a:1-102 [93926]
    15. 1p2h
      complexed with fad, hem, na, teo; mutant
      1. region a:1-102 [93930]
    16. 1qo8
      complexed with fad, hem
      1. region a:2-102 [19696]
      2. region d:2-102 [19697]
  2. Shewanella putrefaciens [TaxId: 24] [48723] (3)
    1. 1d4d
      1. region a:4-102 [19702]
    2. 1d4c
      1. region a:1-102 [19698]
      2. region b:3-102 [19699]
      3. region c:3-102 [19700]
      4. region d:1-102 [19701]
    3. 1d4e
      1. region a:4-102 [19703]
  3. Shewanella oneidensis [TaxId: 70863] [74808] (3)
    1. 1m1q
      complexed with hem, sul
      1. chain a [74419]
    2. 1m1r
      complexed with hem, sul
      1. chain a [74420]
    3. 1m1p
      complexed with hem, sul
      1. chain a [74413]
      2. chain b [74414]
      3. chain c [74415]
      4. chain d [74416]
      5. chain e [74417]
      6. chain f [74418]
7. Putative Cytochrome c [110040]
  1. Shewanella oneidensis [TaxId: 70863] [110041] (1)
    SQ Q8E9W8 # SO4144
    1. 1sp3
      complexed with hem, scn
      1. chain a [105866]