Superfamily: Terpenoid synthases

duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
uperfamily

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]
3. Fold: Terpenoid synthases [48575]
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
4. Superfamily: Terpenoid synthases [48576]
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
   uperfamily

Families:

1. Isoprenyl diphosphate synthases [48577] (5)
   1. Farnesyl diphosphate synthase (geranyltranstransferase) [48578]
      1. Chicken (Gallus gallus) [TaxId: 9031] [48579] (5)
      2. Escherichia coli [TaxId: 562] [101453] (2)
      3. Staphylococcus aureus [TaxId: 1280] [101454] (1)
   2. Octoprenyl-diphosphate synthase [101455]
      1. Thermotoga maritima [TaxId: 2336] [101456] (10)
         SQ Q9X1M1
   3. Geranylgeranyl pyrophosphate synthetase [158813]
      1. Human (Homo sapiens) [TaxId: 9606] [158814] (6)
         SQ O95749 6-296
2. Squalene synthase [48580] (1)
   1. Squalene synthase [48581]
      synonym: Farnesyl diphosphate farnesyltransferase
      1. Human (Homo sapiens) [TaxId: 9606] [48582] (1)
3. Terpenoid cyclase C-terminal domain [48583] (2)
   1. 5-Epi-aristolochene synthase [48584]
      1. Tobacco (Nicotiana tabacum) [TaxId: 4097] [48585] (7)
   2. (+)-bornyl diphosphate synthase [81920]
      1. Garden sage (Salvia officinalis) [TaxId: 38868] [81921] (7)
4. Aristolochene/pentalenene synthase [48586] (2)
   1. Aristolochene synthase [48587]
      1. Fungus (Penicillium roqueforti) [TaxId: 5082] [48588] (2)
   2. Pentalenene synthase [48589]
      1. Streptomyces sp., UC5319 [TaxId: 1931] [48590] (3)
5. Trichodiene synthase [69113] (1)
   1. Trichodiene synthase [69114]
      1. Fusarium sporotrichioides [TaxId: 5514] [69115] (12)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk