Structural Classification of Proteins

Fold: Terpenoid synthases

: multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: Terpenoid synthases [48575]
multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

Superfamilies:

Terpenoid synthases [48576] (5)
duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
uperfamily
1. Isoprenyl diphosphate synthases [48577] (5)
  1. Farnesyl diphosphate synthase (geranyltranstransferase) [48578]
    1. Chicken (Gallus gallus) [TaxId: 9031] [48579] (5)
    2. Escherichia coli [TaxId: 562] [101453] (2)
    3. Staphylococcus aureus [TaxId: 1280] [101454] (1)
  2. Octoprenyl-diphosphate synthase [101455]
    1. Thermotoga maritima [TaxId: 2336] [101456] (10)
      SQ Q9X1M1
  3. Geranylgeranyl pyrophosphate synthetase [158813]
    1. Human (Homo sapiens) [TaxId: 9606] [158814] (6)
      SQ O95749 6-296
2. Squalene synthase [48580] (1)
  1. Squalene synthase [48581]
    synonym: Farnesyl diphosphate farnesyltransferase
    1. Human (Homo sapiens) [TaxId: 9606] [48582] (1)
3. Terpenoid cyclase C-terminal domain [48583] (2)
  1. 5-Epi-aristolochene synthase [48584]
    1. Tobacco (Nicotiana tabacum) [TaxId: 4097] [48585] (7)
  2. (+)-bornyl diphosphate synthase [81920]
    1. Garden sage (Salvia officinalis) [TaxId: 38868] [81921] (7)
4. Aristolochene/pentalenene synthase [48586] (2)
  1. Aristolochene synthase [48587]
    1. Fungus (Penicillium roqueforti) [TaxId: 5082] [48588] (2)
  2. Pentalenene synthase [48589]
    1. Streptomyces sp., UC5319 [TaxId: 1931] [48590] (3)
5. Trichodiene synthase [69113] (1)
  1. Trichodiene synthase [69114]
    1. Fusarium sporotrichioides [TaxId: 5514] [69115] (12)