Structural Classification of Proteins

Family: Protein prenylyltransferase

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: alpha-alpha superhelix [48370]
multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
Superfamily: Protein prenylyltransferase [48439]
uperfamily
Family: Protein prenylyltransferase [48440]

Protein Domains:

Protein farnesyltransferase alpha-subunit [48441]
1. Rat (Rattus norvegicus) [TaxId: 10116] [48442] (29)
  SQ Q04631 55-369
  1. 1d8d
    complex with K-ras4b peptide substrate
    1. chain a [19185]
  2. 1jcr
    complexed with acy, fpp, zn
    1. chain a [66506]
  3. 1kzp
    complex with k-ras4b peptide product
    complexed with acy, far, zn
    1. chain a [77640]
  4. 1jcs
    complexed with acy, fii, zn
    1. chain a [66508]
  5. 1kzo
    complex with k-ras4b peptide product and farnesyl diphosphate substrate bound simultaneously
    complexed with acy, far, fpp, zn
    1. chain a [77638]
  6. 2r2l
    automatically matched to d1o1ra_
    complexed with fpp, pb9, zn
    1. region a:54-368 [151535]
  7. 1o1t
    complexed with 2nh, mg, zn
    1. chain a [86551]
  8. 1o5m
    complexed with 336, fpp, zn
    1. chain a [92507]
  9. 1o1r
    complexed with grg, zn
    1. chain a [86547]
  10. 1o1s
    complexed with 1nh, zn
    1. chain a [86549]
  11. 1ft1
    complexed with zn
    1. chain a [19186]
  12. 1sa5
    complexed with acy, bmv, fpp, zn
    1. chain a [105404]
  13. 1s64
    complexed with 778, cl, mes, so4, zn
    1. chain a [105287]
    2. chain c [105289]
    3. chain e [105291]
    4. chain g [105293]
    5. chain i [105295]
    6. chain k [105297]
  14. 1n4q
    complexed with cl, mgm, tth, zn
    1. chain a [91635]
    2. chain c [91637]
    3. chain e [91639]
    4. chain g [91641]
    5. chain i [91643]
    6. chain k [91645]
  15. 1n4s
    complexed with cl, grg, tth, zn
    1. chain a [91659]
    2. chain c [91661]
    3. chain e [91663]
    4. chain g [91665]
    5. chain i [91667]
    6. chain k [91669]
  16. 2bed
    automatically matched to d1o1ra_
    complexed with 736, fpp, zn
    1. region a:54-366 [128375]
  17. 1qbq
    complexed with ace, act, hfp, zn
    1. chain a [19187]
  18. 1n4p
    complexed with cl, grg, tth, zn
    1. chain a [91623]
    2. chain c [91625]
    3. chain e [91627]
    4. chain g [91629]
    5. chain i [91631]
    6. chain k [91633]
  19. 3dpy
    automatically matched to d1d8da_
    complexed with acy, fpp, zn
    1. region a:55-377 [157825]
  20. 1n4r
    complexed with cl, mes, so4, tth, zn
    1. chain a [91647]
    2. chain c [91649]
    3. chain e [91651]
    4. chain g [91653]
    5. chain i [91655]
    6. chain k [91657]
  21. 1d8e
    complex with k-ras4b peptide substrate and FPP analog
    complexed with ace, fii
    1. chain a [19188]
  22. 1nl4
    complexed with ftl, hfp, zn; mutant
    1. chain a [80617]
  23. 1n95
    complexed with fth, hfp, zn
    1. chain a [80333]
  24. 1ft2
    complexed with fpp, zn
    1. chain a [19190]
  25. 1fpp
    complexed with fpp, po4, zn
    1. chain a [19189]
  26. 1ni1
    complexed with 2c5, hfp, zn
    1. chain a [91888]
  27. 1x81
    complexed with jan, zn
    1. chain a [114953]
  28. 1n9a
    complexed with fti, hfp, zn
    1. chain a [80338]
  29. 1n94
    complexed with hfp, tin, zn
    1. chain a [80331]
2. Human (Homo sapiens) [TaxId: 9606] [69093] (20)
  SQ P49354
  1. 2h6f
    automatically matched to d1s63a_
    complexed with acy, far, suc, zn; mutant
    1. region a:55-369 [136185]
  2. 2h6h
    automatically matched to d1s63a_
    complexed with acy, far, suc, zn; mutant
    1. region a:55-369 [136188]
  3. 1tn6
    complexed with acy, fii, suc, zn; mutant
    1. chain a [112527]
  4. 2iej
    automatically matched to d1s63a_
    complexed with act, fii, s48, suc, zn
    1. region a:55-369 [137313]
  5. 1s63
    complexed with 778, fpp, suc, zn
    1. chain a [105285]
  6. 1ld8
    complexed with acy, fpp, suc, u49, zn
    1. chain a [73838]
  7. 2h6g
    automatically matched to d1s63a_
    complexed with ger, suc, zn; mutant
    1. region a:55-369 [136187]
  8. 1mzc
    complexed with bne, fpp, suc, zn
    1. chain a [85239]
  9. 1sa4
    complexed with fpp, jan, suc, zn
    1. chain a [105402]
  10. 1ld7
    complexed with fpp, suc, u66, zn
    1. chain a [73836]
  11. 1jcq
    complexed with 739, acy, fpp, suc, zn; mutant
    1. chain a [66504]
  12. 1tn7
    complexed with acy, fii, zn
    1. chain a [112529]
  13. 1tn8
    complexed with acy, fii, zn; mutant
    1. chain a [112531]
  14. 1tno
    complexed with cl, mes, mgm, zn
    1. chain a [112545]
    2. chain c [112547]
    3. chain e [112549]
    4. chain g [112551]
    5. chain i [112553]
    6. chain k [112555]
  15. 1tny
    complexed with cl, mes, mgm, zn
    1. chain a [112569]
    2. chain c [112571]
    3. chain e [112573]
    4. chain g [112575]
    5. chain i [112577]
    6. chain k [112579]
  16. 1tnu
    complexed with cl, mes, mgm, zn
    1. chain a [112557]
    2. chain c [112559]
    3. chain e [112561]
    4. chain g [112563]
    5. chain i [112565]
    6. chain k [112567]
  17. 1tnb
    complexed with cl, mes, mgm, zn
    1. chain a [112533]
    2. chain c [112535]
    3. chain e [112537]
    4. chain g [112539]
    5. chain i [112541]
    6. chain k [112543]
  18. 1tnz
    complexed with cl, mes, mgm, zn
    1. chain a [112581]
    2. chain c [112583]
    3. chain e [112585]
    4. chain g [112587]
    5. chain i [112589]
    6. chain k [112591]
  19. 2f0y
    automatically matched to d1s63a_
    complexed with 3mn, fpp, zn
    1. region a:55-368 [132681]
  20. 2h6i
    automatically matched to d1s63a_
    complexed with ger, suc, zn; mutant
    1. region a:55-369 [136189]
Rab geranylgeranyltransferase alpha-subunit, N-terminal domain [48443]
1. Rat (Rattus norvegicus) [TaxId: 10116] [48444] (2)
  1. 1dce
    complexed with zn
    1. region a:1-241,a:351-443 [19191]
    2. region c:1-241,c:351-443 [19192]
  2. 1ltx
    complexed with cl, far, zn2; mutant
    1. region a:24-241,a:351-443 [84711]