Structural Classification of Proteins
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Family: Tetratricopeptide repeat (TPR)

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: alpha-alpha superhelix [48370]
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. Superfamily: TPR-like [48452]
    link to SUPERFAMILY database - Superfamily
  5. Family: Tetratricopeptide repeat (TPR) [48453]

Protein Domains:

  1. Protein phosphatase 5 [48454]
    1. Human (Homo sapiens) [TaxId: 9606] [48455] (6)
      1. 1a17 picpic
        complexed with so4
        1. chain a [19206] picpiclink
      2. 1wao picpicxrefxrefxrefxref
        automatically matched to d1a17__
        complexed with mn
        1. region 1:23-175 [120813] picpiclink
      3. 1wao picpicxrefxrefxrefxref
        automatically matched to d1a17__
        complexed with mn
        1. region 2:23-175 [120815] picpiclink
      4. 1wao picpicxrefxrefxrefxref
        automatically matched to d1a17__
        complexed with mn
        1. region 3:23-175 [120817] picpiclink
      5. 1wao picpicxrefxrefxrefxref
        automatically matched to d1a17__
        complexed with mn
        1. region 4:23-175 [120819] picpiclink
      6. 2bug picpic
        complexed with ace; mutant
        1. region a:18-147 [129203] picpiclink
  2. Hop [48456]
    1. Human (Homo sapiens) [TaxId: 9606] [48457] (2)
      1. 1elw picpic
        TPR1-domain
        complexed with ni, trs
        1. chain a [19207] picpiclink
        2. chain b [19208] picpiclink
      2. 1elr picpic
        TPR2-domain
        complexed with ace, ni
        1. chain a [19209] picpiclink
  3. Vesicular transport protein sec17 [48458]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [48459] (1)
      1. 1qqe picpic
        mutant
        1. chain a [19210] picpiclink
  4. Neutrophil cytosolic factor 2 (NCF-2, p67-phox) [48460]
    1. Human (Homo sapiens) [TaxId: 9606] [48461] (3)
      1. 1hh8 picpic
        complexed with flc; mutant
        1. chain a [61042] picpiclink
      2. 1wm5 picpic
        automatically matched to d1e96b_
        complexed with so4
        1. region a:2-186 [121028] picpiclink
      3. 1e96 picpicxref
        complexed with gtp, mg; mutant
        1. chain b [19211] picpiclink
  5. Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) [48462]
    1. Human (Homo sapiens) [TaxId: 9606] [48463] (6)
      1. 1fch picpic
        complexed with the pts1 peptide
        1. chain a [19212] picpiclink
        2. chain b [19213] picpiclink
      2. 2j9q picpic
        automatically matched to d1fcha_
        complexed with sr
        1. region a:321-639 [138152] picpiclink
      3. 2c0m picpic
        automatically matched to d1fcha_
        1. region a:284-602 [129596] picpiclink
      4. 2c0m picpic
        automatically matched to d1fcha_
        1. region b:284-602 [129597] picpiclink
      5. 2c0m picpic
        automatically matched to d1fcha_
        1. region c:285-602 [129598] picpiclink
      6. 2c0m picpic
        automatically matched to d1fcha_
        1. region f:285-602 [129599] picpiclink
    2. Trypanosoma brucei [TaxId: 5691] [63617] (1)
      1. 1hxi picpic
        complexed with mg
        1. chain a [61366] picpiclink
  6. Cyclophilin 40 [63618]
    1. Cow (Bos taurus) [TaxId: 9913] [63619] (2)
      1. 1ihg picpicxref
        complexed with gol
        1. region a:197-365 [62380] picpiclink
      2. 1iip picpicxref
        truncated form(?); adopts a different fold
        complexed with gol
        1. region a:197-298 [62451] picpiclink
  7. FKBP51, C-terminal domain [81905]
    1. Human (Homo sapiens) [TaxId: 9606] [81906] (1)
      1. 1kt0 picpicxref
        complexed with so4; mutant
        1. region a:254-412 [77525] picpiclink
    2. Monkey (Saimiri boliviensis) [TaxId: 27679] [81907] (1)
      1. 1kt1 picpicxref
        complexed with so4
        1. region a:254-421 [77528] picpiclink
  8. Hypothetical protein RSGI Ruh-001 [81908]
    a Fis1p-like and Cgi-135 homologous domain
    1. Mouse (Mus musculus) [TaxId: 10090] [81909] (1)
      1. 1iyg picpic
        structural genomics
        1. chain a [76947] picpiclink
  9. Mitochondria fission protein Fis1 [101417]
    1. Human (Homo sapiens) [TaxId: 9606] [101418] (2)
      1. 1nzn picpic
        complexed with gol, so4
        1. chain a [92382] picpiclink
      2. 1pc2 picpic
        1. chain a [94427] picpiclink
    2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [140836] (3)
      SQ P40515 1-138
      1. 2pqr picpic
        automatically matched to d1y8ma1
        complexed with au
        1. region b:5-128 [149793] picpiclink
      2. 2pqn picpic
        automatically matched to d1y8ma1
        1. region a:4-129 [149792] picpiclink
      3. 1y8m picpic
        1. region a:1-138 [122757] picpiclink
  10. FKBP52 (FKBP4), C-terminal domain [109971]
    1. Human (Homo sapiens) [TaxId: 9606] [109972] (2)
      SQ Q02790 145-427
      1. 1p5q picpicxref
        second FKPB domain
        complexed with so4
        1. region a:258-427 [104068] picpiclink
        2. region b:258-427 [104070] picpiclink
        3. region c:258-427 [104072] picpiclink
      2. 1qz2 picpicxref
        second FKPB domain
        1. region a:258-425 [104663] picpiclink
        2. region b:258-425 [104665] picpiclink
        3. region c:258-425 [104667] picpiclink
  11. O-GlcNAc transferase p110 subunit, OGT [109973]
    1. Human (Homo sapiens) [TaxId: 9606] [109974] (1)
      SQ O15294 16-400
      1. 1w3b picpic
        complexed with ca
        1. chain a [109149] picpiclink
        2. chain b [109150] picpiclink
  12. Prolyl 4-hydroxylase alpha-1 subunit, P4HA1 [117007]
    1. Human (Homo sapiens) [TaxId: 9606] [117008] (1)
      SQ P13674 161-254
      1. 1tjc picpic
        mutant
        1. chain a [112440] picpiclink
        2. chain b [112441] picpiclink
  13. Lipoprotein NlpI [117009]
    1. Escherichia coli [TaxId: 562] [117010] (1)
      SQ P39833 26-294
      1. 1xnf picpic
        Structural genomics target
        complexed with tmn
        1. chain a [115580] picpiclink
        2. chain b [115581] picpiclink
  14. STIP1 homology and U box-containing protein 1, STUB1 [140837]
    1. Mouse (Mus musculus) [TaxId: 10090] [140838] (4)
      SQ Q9WUD1 24-224
      1. 2c2l picpicxrefxrefxrefxref
        includes linker region 157-224 that forms an alpha hairpin dimerisation subdomain
        complexed with ni, so4
        1. region a:24-224 [129672] picpiclink
      2. 2c2l picpicxrefxrefxrefxref
        automatically matched to 2C2L A:24-224
        complexed with ni, so4
        1. region b:24-224 [129674] picpiclink
      3. 2c2l picpicxrefxrefxrefxref
        automatically matched to 2C2L A:24-224
        complexed with ni, so4
        1. region c:24-224 [129676] picpiclink
      4. 2c2l picpicxrefxrefxrefxref
        automatically matched to 2C2L A:24-224
        complexed with ni, so4
        1. region d:24-224 [129678] picpiclink
  15. Mitochondrial import receptor subunit tom20-3 [140839]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [140840] (1)
      SQ P82874 1-145
      1. 1zu2 picpic
        1. region a:1-145 [125662] picpiclink
  16. Putative 70 kda peptidylprolyl isomerase PFL2275c [140841]
    1. Plasmodium falciparum [TaxId: 5833] [140842] (2)
      SQ Q8I4V8 128-280
      1. 2fbn picpic
        1. region a:22-174 [133254] picpiclink
      2. 2fbn picpic
        automatically matched to 2FBN A:22-174
        1. region b:25-174 [133255] picpiclink
  17. SMG-7 [140843]
    1. Human (Homo sapiens) [TaxId: 9606] [140844] (2)
      SQ Q92540 1-497
      1. 1ya0 picpic
        complexed with so4
        1. region a:1-497 [122785] picpiclink
      2. 1ya0 picpic
        automatically matched to 1YA0 A:1-497
        complexed with so4
        1. region b:1-497 [122786] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk