Structural Classification of Proteins
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Family: Protein prenyltransferases

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: alpha/alpha toroid [48207]
    multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies
  4. Superfamily: Terpenoid cyclases/Protein prenyltransferases [48239]
    link to SUPERFAMILY database - Superfamily
  5. Family: Protein prenyltransferases [48246]

Protein Domains:

  1. Protein farnesyltransferase, beta-subunit [48247]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [48248] (29)
      SQ Q02293 22-418 P53610
      1. 1d8d picpicxref
        complex with K-ras4b peptide substrate
        1. chain b [18866] picpiclink
      2. 1jcr picpicxref
        complexed with acy, fpp, zn
        1. chain b [66507] picpiclink
      3. 1kzp picpicxref
        complex with k-ras4b peptide product
        complexed with acy, far, zn
        1. chain b [77641] picpiclink
      4. 1jcs picpicxref
        complexed with acy, fii, zn
        1. chain b [66509] picpiclink
      5. 1kzo picpicxref
        complex with k-ras4b peptide product and farnesyl diphosphate substrate bound simultaneously
        complexed with acy, far, fpp, zn
        1. chain b [77639] picpiclink
      6. 2r2l picpicxref
        automatically matched to d1ft1b_
        complexed with fpp, pb9, zn
        1. region b:23-423 [151536] picpiclink
      7. 1o1t picpicxref
        complexed with 2nh, mg, zn
        1. chain b [86552] picpiclink
      8. 1o5m picpicxref
        complexed with 336, fpp, zn
        1. chain b [92508] picpiclink
      9. 1o1r picpicxref
        complexed with grg, zn
        1. chain b [86548] picpiclink
      10. 1o1s picpicxref
        complexed with 1nh, zn
        1. chain b [86550] picpiclink
      11. 1ft1 picpicxref
        complexed with zn
        1. chain b [18867] picpiclink
      12. 1sa5 picpicxref
        complexed with acy, bmv, fpp, zn
        1. chain b [105405] picpiclink
      13. 1s64 picpicxref
        complexed with 778, cl, mes, so4, zn
        1. chain b [105288] picpiclink
        2. chain d [105290] picpiclink
        3. chain f [105292] picpiclink
        4. chain h [105294] picpiclink
        5. chain j [105296] picpiclink
        6. chain l [105298] picpiclink
      14. 1n4q picpicxref
        complexed with cl, mgm, tth, zn
        1. chain b [91636] picpiclink
        2. chain d [91638] picpiclink
        3. chain f [91640] picpiclink
        4. chain h [91642] picpiclink
        5. chain j [91644] picpiclink
        6. chain l [91646] picpiclink
      15. 1n4s picpicxref
        complexed with cl, grg, tth, zn
        1. chain b [91660] picpiclink
        2. chain d [91662] picpiclink
        3. chain f [91664] picpiclink
        4. chain h [91666] picpiclink
        5. chain j [91668] picpiclink
        6. chain l [91670] picpiclink
      16. 2bed picpicxref
        automatically matched to d1ft1b_
        complexed with 736, fpp, zn
        1. region b:23-423 [128376] picpiclink
      17. 1qbq picpicxref
        complexed with ace, act, hfp, zn
        1. chain b [18868] picpiclink
      18. 1n4p picpicxref
        complexed with cl, grg, tth, zn
        1. chain b [91624] picpiclink
        2. chain d [91626] picpiclink
        3. chain f [91628] picpiclink
        4. chain h [91630] picpiclink
        5. chain j [91632] picpiclink
        6. chain l [91634] picpiclink
      19. 3dpy picpicxref
        automatically matched to d1ft1b_
        complexed with acy, fpp, zn
        1. region b:22-423 [157826] picpiclink
      20. 1n4r picpicxref
        complexed with cl, mes, so4, tth, zn
        1. chain b [91648] picpiclink
        2. chain d [91650] picpiclink
        3. chain f [91652] picpiclink
        4. chain h [91654] picpiclink
        5. chain j [91656] picpiclink
        6. chain l [91658] picpiclink
      21. 1d8e picpicxref
        complex with k-ras4b peptide substrate and FPP analog
        complexed with ace, fii
        1. chain b [18869] picpiclink
      22. 1nl4 picpicxref
        complexed with ftl, hfp, zn; mutant
        1. chain b [80618] picpiclink
      23. 1n95 picpicxref
        complexed with fth, hfp, zn
        1. chain b [80334] picpiclink
      24. 1ft2 picpicxref
        complexed with fpp, zn
        1. chain b [18871] picpiclink
      25. 1fpp picpicxref
        complexed with fpp, po4, zn
        1. chain b [18870] picpiclink
      26. 1ni1 picpicxref
        complexed with 2c5, hfp, zn
        1. chain b [91889] picpiclink
      27. 1x81 picpicxref
        complexed with jan, zn
        1. chain b [114954] picpiclink
      28. 1n9a picpicxref
        complexed with fti, hfp, zn
        1. chain b [80339] picpiclink
      29. 1n94 picpicxref
        complexed with hfp, tin, zn
        1. chain b [80332] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [69090] (19)
      SQ P49356
      1. 2h6f picpicxref
        automatically matched to d1jcqb_
        complexed with acy, far, suc, zn; mutant
        1. region b:521-921 [136186] picpiclink
      2. 2h6h picpicxref
        complexed with acy, far, suc, zn; mutant
        1. region b:515-924 [145283] picpiclink
      3. 1tn6 picpicxref
        complexed with acy, fii, suc, zn; mutant
        1. chain b [112528] picpiclink
      4. 2iej picpicxref
        automatically matched to d1jcqb_
        complexed with act, fii, s48, suc, zn
        1. region b:521-921 [137314] picpiclink
      5. 1s63 picpicxref
        complexed with 778, fpp, suc, zn
        1. chain b [105286] picpiclink
      6. 1ld8 picpicxref
        complexed with acy, fpp, suc, u49, zn
        1. chain b [73839] picpiclink
      7. 1mzc picpicxref
        complexed with bne, fpp, suc, zn
        1. chain b [85240] picpiclink
      8. 1sa4 picpicxref
        complexed with fpp, jan, suc, zn
        1. chain b [105403] picpiclink
      9. 1ld7 picpicxref
        complexed with fpp, suc, u66, zn
        1. chain b [73837] picpiclink
      10. 1jcq picpicxref
        complexed with 739, acy, fpp, suc, zn; mutant
        1. chain b [66505] picpiclink
      11. 1tn7 picpicxref
        complexed with acy, fii, zn
        1. chain b [112530] picpiclink
      12. 1tn8 picpicxref
        complexed with acy, fii, zn; mutant
        1. chain b [112532] picpiclink
      13. 1tno picpicxref
        complexed with cl, mes, mgm, zn
        1. chain b [112546] picpiclink
        2. chain d [112548] picpiclink
        3. chain f [112550] picpiclink
        4. chain h [112552] picpiclink
        5. chain j [112554] picpiclink
        6. chain l [112556] picpiclink
      14. 1tny picpicxref
        complexed with cl, mes, mgm, zn
        1. chain b [112570] picpiclink
        2. chain d [112572] picpiclink
        3. chain f [112574] picpiclink
        4. chain h [112576] picpiclink
        5. chain j [112578] picpiclink
        6. chain l [112580] picpiclink
      15. 1tnu picpicxref
        complexed with cl, mes, mgm, zn
        1. chain b [112558] picpiclink
        2. chain d [112560] picpiclink
        3. chain f [112562] picpiclink
        4. chain h [112564] picpiclink
        5. chain j [112566] picpiclink
        6. chain l [112568] picpiclink
      16. 1tnb picpicxref
        complexed with cl, mes, mgm, zn
        1. chain b [112534] picpiclink
        2. chain d [112536] picpiclink
        3. chain f [112538] picpiclink
        4. chain h [112540] picpiclink
        5. chain j [112542] picpiclink
        6. chain l [112544] picpiclink
      17. 1tnz picpicxref
        complexed with cl, mes, mgm, zn
        1. chain b [112582] picpiclink
        2. chain d [112584] picpiclink
        3. chain f [112586] picpiclink
        4. chain h [112588] picpiclink
        5. chain j [112590] picpiclink
        6. chain l [112592] picpiclink
      18. 2f0y picpicxref
        automatically matched to d1jcqb_
        complexed with 3mn, fpp, zn
        1. region b:21-421 [132682] picpiclink
      19. 2h6i picpicxref
        complexed with ger, suc, zn; mutant
        1. region b:515-924 [145284] picpiclink
  2. Rab geranylgeranyltransferase, beta subunit [48249]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [48250] (9)
      1. 3dss picpic
        automatically matched to d1dceb_
        complexed with ca, zn
        1. region b:7-331 [157841] picpiclink
      2. 3dst picpic
        automatically matched to d1dceb_
        complexed with ca, grg, zn
        1. region b:7-331 [157842] picpiclink
      3. 3dsu picpic
        automatically matched to d1dceb_
        complexed with ca, fpp, zn
        1. region b:7-331 [157843] picpiclink
      4. 3dsv picpic
        automatically matched to d1dceb_
        complexed with ca, ger, zn
        1. region b:7-331 [157844] picpiclink
      5. 3dsx picpic
        automatically matched to d1dceb_
        complexed with ca, ger, zn
        1. region b:7-331 [157846] picpiclink
      6. 3dsw picpic
        automatically matched to d1dceb_
        complexed with ca, ger, zn
        1. region b:7-330 [157845] picpiclink
      7. 1dce picpicxrefxrefxref
        complexed with zn
        1. chain b [18872] picpiclink
        2. chain d [18873] picpiclink
      8. 3c72 picpic
        automatically matched to d1dceb_
        complexed with ca, cx1, zn
        1. region b:7-331 [155997] picpiclink
      9. 1ltx picpicxrefxrefxrefxrefxref
        complexed with cl, far, zn2; mutant
        1. chain b [84714] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk