Superfamily: Terpenoid cyclases/Protein prenyltransferases

uperfamily

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]
3. Fold: alpha/alpha toroid [48207]
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies
4. Superfamily: Terpenoid cyclases/Protein prenyltransferases [48239]
   uperfamily

Families:

1. Terpenoid cyclase N-terminal domain [48240] (2)
   incomplete toroid made of four hairpins
   1. 5-Epi-aristolochene synthase [48241]
      1. Tobacco (Nicotiana tabacum) [TaxId: 4097] [48242] (7)
   2. (+)-bornyl diphosphate synthase [81857]
      1. Garden sage (Salvia officinalis) [TaxId: 38868] [81858] (7)
2. Terpene synthases [48243] (2)
   consists of two toroid domains: one of six and one of five hairpins
   1. Squalene-hopene cyclase [48244]
      1. Alicyclobacillus acidocaldarius [TaxId: 405212] [48245] (16)
   2. Lanosterol synthase [116989]
      1. Human (Homo sapiens) [TaxId: 9606] [116990] (2)
         SQ P48449
3. Protein prenyltransferases [48246] (3)
   1. Protein farnesyltransferase, beta-subunit [48247]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [48248] (29)
         SQ Q02293 22-418 P53610
      2. Human (Homo sapiens) [TaxId: 9606] [69090] (19)
         SQ P49356
   2. Rab geranylgeranyltransferase, beta subunit [48249]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [48250] (9)
4. Complement components [48251] (3)
   probably related to other families, but has no known enzymatic activity
   1. C3D, a C3 fragment and ligand for complement receptor 2 [48252]
      1. Human (Homo sapiens) [TaxId: 9606] [48253] (11)
      2. Rat (Rattus norvegicus) [TaxId: 10116] [48254] (2)
   2. C4adg fragment of complement factor C4a [81859]
      1. Human (Homo sapiens) [TaxId: 9606] [81860] (1)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk