Structural Classification of Proteins
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Family: Hyaluronate lyase-like catalytic, N-terminal domain

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: alpha/alpha toroid [48207]
    multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies
  4. Superfamily: Chondroitin AC/alginate lyase [48230]
    incomplete toroid
    link to SUPERFAMILY database - Superfamily
  5. Family: Hyaluronate lyase-like catalytic, N-terminal domain [48234]

Protein Domains:

  1. Chondroitinase AC [48235]
    Chondroitin AC lyase
    1. Pedobacter heparinus (Flavobacterium heparinum) [TaxId: 984] [48236] (5)
      1. 1cb8 picpicxrefxref
        complexed with ca, gcu, gol, man, mfu, ram, xys
        1. region a:26-335 [18849] picpiclink
      2. 1hmu picpicxrefxref
        complexed with ca, gcu, idt, man, mxy, ngl, ram, xys; mutant
        1. region a:26-335 [61089] picpiclink
      3. 1hm2 picpicxrefxref
        complexed with ca, gcu, idr, man, mxy, ngl, ram, xys; mutant
        1. region a:26-335 [61083] picpiclink
      4. 1hm3 picpicxrefxref
        complexed with ca, gcu, man, mxy, nag, ram, xys; mutant
        1. region a:26-335 [61086] picpiclink
      5. 1hmw picpicxrefxref
        complexed with ca, gcd, gcu, man, mxy, ng6, ngl, ram, xys; mutant
        1. region a:26-335 [61092] picpiclink
    2. Arthrobacter aurescens [TaxId: 43663] [101368] (6)
      1. 1rwh picpicxrefxref
        complexed with gad, gct, gol, na, ngl, po4
        1. region a:4-372 [97984] picpiclink
      2. 1rwa picpicxrefxref
        complexed with gol, hg
        1. region a:4-372 [97967] picpiclink
      3. 1rw9 picpicxrefxref
        complexed with na, po4
        1. region a:4-372 [97964] picpiclink
      4. 1rwf picpicxrefxref
        complexed with gad, gct, na, ngl, po4
        1. region a:4-372 [97978] picpiclink
      5. 1rwg picpicxrefxref
        complexed with gad, gct, na, ngl, po4
        1. region a:4-372 [97981] picpiclink
      6. 1rwc picpicxrefxref
        complexed with gad, gol, na, nag, po4
        1. region a:4-372 [97974] picpiclink
  2. Hyaluronate lyase [48237]
    1. Streptococcus pneumoniae [TaxId: 1313] [48238] (19)
      SQ Q54873 287-1007
      1. 1n7o picpicxrefxref
        mutant
        1. region a:170-540 [80259] picpiclink
      2. 1ojn picpicxrefxref
        complexed with dgc, ng6, so4; mutant
        1. region a:170-540 [93137] picpiclink
      3. 1n7n picpicxrefxref
        mutant
        1. region a:170-540 [80256] picpiclink
      4. 1w3y picpicxrefxref
        complexed with pvc, so4, xyl
        1. region a:170-540 [109168] picpiclink
      5. 1n7p picpicxrefxref
        mutant
        1. region a:170-540 [80262] picpiclink
      6. 1lxk picpicxrefxref
        complexed with gcu, nag; mutant
        1. region a:171-540 [74331] picpiclink
      7. 1ojo picpicxrefxref
        complexed with dgc, ngl, so4; mutant
        1. region a:170-540 [93140] picpiclink
      8. 1egu picpicxrefxref
        complexed with so4
        1. region a:171-540 [18850] picpiclink
      9. 1ojm picpicxrefxref
        complexed with dgc, nga, so4
        1. region a:170-540 [93134] picpiclink
      10. 1ojp picpicxrefxref
        complexed with dgc, ng6, so4
        1. region a:170-540 [93143] picpiclink
      11. 2brp picpicxrefxref
        automatically matched to d1f9ga1
        complexed with sie, so4, xls
        1. region a:170-540 [129005] picpiclink
      12. 1c82 picpicxrefxref
        complexed with cac, gc4, na, nag
        1. region a:171-540 [59079] picpiclink
      13. 1n7r picpicxrefxref
        complexed with gcu, nag; mutant
        1. region a:170-540 [80268] picpiclink
      14. 1f9g picpicxrefxref
        complexed with asc
        1. region a:170-540 [59738] picpiclink
      15. 1loh picpicxrefxref
        complexed with gcu, nag; mutant
        1. region a:170-540 [74147] picpiclink
      16. 1n7q picpicxrefxref
        complexed with gcu, nag; mutant
        1. region a:170-540 [80265] picpiclink
      17. 2brw picpicxrefxrefxrefxref
        automatically matched to d1f9ga1
        complexed with so4
        1. region a:170-540 [129022] picpiclink
      18. 2brw picpicxrefxrefxrefxref
        automatically matched to d1f9ga1
        complexed with so4
        1. region b:170-540 [129025] picpiclink
      19. 2brv picpicxrefxref
        automatically matched to d1f9ga1
        complexed with mla
        1. region x:170-540 [129019] picpiclink
    2. Streptococcus agalactiae [TaxId: 1311] [69089] (3)
      preceded by a small all-beta Ig-like domain
      1. 1f1s picpicxrefxrefxref
        1. region a:249-619 [64928] picpiclink
      2. 1lxm picpicxrefxrefxref
        complexed with gcu, nag
        1. region a:249-619 [78296] picpiclink
      3. 1i8q picpicxrefxrefxref
        complexed with gc4, nag
        1. region a:249-619 [66090] picpiclink
  3. Xanthan lyase [89111]
    1. Bacillus sp. gl1 [TaxId: 84635] [89112] (7)
      1. 1x1i picpicxrefxref
        automatically matched to d1j0ma1
        complexed with 46m; mutant
        1. region a:26-386 [121584] picpiclink
      2. 2e24 picpicxrefxref
        automatically matched to d1j0ma1
        complexed with peg; mutant
        1. region a:26-386 [131976] picpiclink
      3. 1x1j picpicxrefxref
        automatically matched to d1j0ma1
        complexed with 46d, ca; mutant
        1. region a:26-386 [121587] picpiclink
      4. 1x1h picpicxrefxref
        automatically matched to d1j0ma1
        mutant
        1. region a:26-386 [121581] picpiclink
      5. 2e22 picpicxrefxref
        automatically matched to d1j0ma1
        complexed with man
        1. region a:26-386 [131973] picpiclink
      6. 1j0m picpicxrefxref
        complexed with ca
        1. region a:26-386 [83910] picpiclink
      7. 1j0n picpicxrefxref
        complexed with ca, ceg
        1. region a:26-386 [83913] picpiclink
  4. Chondroitin ABC lyase I [89113]
    domain 2; preceded by a beta-domain of the galactose-binding domain-like fold
    1. Proteus vulgaris [TaxId: 585] [89114] (1)
      1. 1hn0 picpicxrefxrefxref
        complexed with na
        1. region a:235-618 [83616] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk