Structural Classification of Proteins
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Family: BAR domain

sensor of membrane curvature

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: BAR/IMD domain-like [116747]
    6 helices, homodimer of 3-helical domains
  4. Superfamily: BAR/IMD domain-like [103657]
    core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
    link to SUPERFAMILY database - Superfamily
  5. Family: BAR domain [103658]
    sensor of membrane curvature

Protein Domains:

  1. Amphiphysin [103659]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [103660] (1)
      1. 1uru picpic
        1. chain a [99835] picpiclink
  2. Endophilin-1 [140699]
    SH3-containing GRB2-like protein 2
    1. Rat (Rattus norvegicus) [TaxId: 10116] [140700] (1)
      SQ Q62420 25-247
      UniProt sequence of Rat species, O35179, is a fragment that does not cover the entire domain
      1. 2c08 picpic
        1. region a:25-247 [129578] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [140701] (6)
      SQ Q99962 11-247! SQ Q99962 26-247
      1. 2d4c picpic
        complexed with ca; mutant
        1. region a:11-247 [131246] picpiclink
      2. 2d4c picpic
        automatically matched to 2D4C A:11-247
        complexed with ca; mutant
        1. region b:11-247 [131247] picpiclink
      3. 2d4c picpic
        automatically matched to 2D4C A:11-247
        complexed with ca; mutant
        1. region c:11-247 [131248] picpiclink
      4. 2d4c picpic
        automatically matched to 2D4C A:11-247
        complexed with ca; mutant
        1. region d:12-247 [131249] picpiclink
      5. 1x04 picpic
        mutant
        1. region a:26-225 [121542] picpiclink
      6. 1x03 picpic
        1. region a:26-247 [121541] picpiclink
    3. Mouse (Mus musculus) [TaxId: 10090] [140702] (2)
      SQ Q62420 27-246
      1. 1zww picpic
        complexed with cd
        1. region a:27-246 [125750] picpiclink
      2. 1zww picpic
        automatically matched to 1ZWW A:27-246
        complexed with cd
        1. region b:28-246 [125751] picpiclink
  3. DCC-interacting protein 13-alpha, APPL1 [158643]
    1. Human (Homo sapiens) [TaxId: 9606] [158644] (1)
      SQ Q9UKG1 6-273
      1. 2elb picpicxref
        1. region a:6-273 [146895] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk