Structural Classification of Proteins

Superfamily: BAR/IMD domain-like

: core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
uperfamily

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: BAR/IMD domain-like [116747]
6 helices, homodimer of 3-helical domains
Superfamily: BAR/IMD domain-like [103657]
core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
uperfamily

BAR domain [103658] (5)
sensor of membrane curvature
1. Amphiphysin [103659]
  1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [103660] (1)
2. Endophilin-1 [140699]
  SH3-containing GRB2-like protein 2
  1. Rat (Rattus norvegicus) [TaxId: 10116] [140700] (1)
    SQ Q62420 25-247
    UniProt sequence of Rat species, O35179, is a fragment that does not cover the entire domain
  2. Human (Homo sapiens) [TaxId: 9606] [140701] (6)
    SQ Q99962 11-247! SQ Q99962 26-247
  3. Mouse (Mus musculus) [TaxId: 10090] [140702] (2)
    SQ Q62420 27-246
3. DCC-interacting protein 13-alpha, APPL1 [158643]
  1. Human (Homo sapiens) [TaxId: 9606] [158644] (1)
    SQ Q9UKG1 6-273
Arfaptin, Rac-binding fragment [64599] (1)
1. Arfaptin, Rac-binding fragment [64600]
  active form is a dimer
  1. Human (Homo sapiens) [TaxId: 9606] [64601] (4)
IMD domain [140703] (1)
Pfam 08397
1. BAP2/IRSp53 N-terminal domain [140704]
  1. Human (Homo sapiens) [TaxId: 9606] [140705] (4)
    SQ Q9UQB8 1-248! SQ Q9UQB8 2-228
FCH domain [158645] (2)
Pfam 00611; Fes/CIP4 homology domain
1. Formin-binding protein 1, FNBP1 [158646]
  1. Human (Homo sapiens) [TaxId: 9606] [158647] (1)
    SQ Q96RU3 1-288
2. CDC42-interacting protein 4, CIP4 [158648]
  1. Human (Homo sapiens) [TaxId: 9606] [158649] (1)
    SQ Q15642 10-288