Structural Classification of Proteins
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Superfamily: BAR/IMD domain-like

core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: BAR/IMD domain-like [116747]
    6 helices, homodimer of 3-helical domains
  4. Superfamily: BAR/IMD domain-like [103657]
    core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
    link to SUPERFAMILY database - Superfamily

Families:

  1. BAR domain [103658] (5)
    sensor of membrane curvature
    1. Amphiphysin [103659]
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [103660] (1)
        1. 1uru picpic
          1. chain a [99835] picpiclink
    2. Endophilin-1 [140699]
      SH3-containing GRB2-like protein 2
      1. Rat (Rattus norvegicus) [TaxId: 10116] [140700] (1)
        SQ Q62420 25-247
        UniProt sequence of Rat species, O35179, is a fragment that does not cover the entire domain
        1. 2c08 picpic
          1. region a:25-247 [129578] picpiclink
      2. Human (Homo sapiens) [TaxId: 9606] [140701] (6)
        SQ Q99962 11-247! SQ Q99962 26-247
        1. 2d4c picpic
          complexed with ca; mutant
          1. region a:11-247 [131246] picpiclink
        2. 2d4c picpic
          automatically matched to 2D4C A:11-247
          complexed with ca; mutant
          1. region b:11-247 [131247] picpiclink
        3. 2d4c picpic
          automatically matched to 2D4C A:11-247
          complexed with ca; mutant
          1. region c:11-247 [131248] picpiclink
        4. 2d4c picpic
          automatically matched to 2D4C A:11-247
          complexed with ca; mutant
          1. region d:12-247 [131249] picpiclink
        5. 1x04 picpic
          mutant
          1. region a:26-225 [121542] picpiclink
        6. 1x03 picpic
          1. region a:26-247 [121541] picpiclink
      3. Mouse (Mus musculus) [TaxId: 10090] [140702] (2)
        SQ Q62420 27-246
        1. 1zww picpic
          complexed with cd
          1. region a:27-246 [125750] picpiclink
        2. 1zww picpic
          automatically matched to 1ZWW A:27-246
          complexed with cd
          1. region b:28-246 [125751] picpiclink
    3. DCC-interacting protein 13-alpha, APPL1 [158643]
      1. Human (Homo sapiens) [TaxId: 9606] [158644] (1)
        SQ Q9UKG1 6-273
        1. 2elb picpicxref
          1. region a:6-273 [146895] picpiclink
  2. Arfaptin, Rac-binding fragment [64599] (1)
    1. Arfaptin, Rac-binding fragment [64600]
      active form is a dimer
      1. Human (Homo sapiens) [TaxId: 9606] [64601] (4)
        1. 1i4d picpicxref
          complexed with gdp, mg
          1. chain a [61682] picpiclink
          2. chain b [61683] picpiclink
        2. 1i4t picpicxref
          complexed with gnp, mg; mutant
          1. chain a [61729] picpiclink
          2. chain b [61730] picpiclink
        3. 1i4l picpicxref
          complexed with gdp, mg
          1. chain a [61718] picpiclink
          2. chain b [61719] picpiclink
        4. 1i49 picpic
          1. chain a [61679] picpiclink
          2. chain b [61680] picpiclink
  3. IMD domain [140703] (1)
    Pfam 08397
    1. BAP2/IRSp53 N-terminal domain [140704]
      1. Human (Homo sapiens) [TaxId: 9606] [140705] (4)
        SQ Q9UQB8 1-248! SQ Q9UQB8 2-228
        1. 1y2o picpic
          1. region a:1-248 [122573] picpiclink
        2. 1y2o picpic
          automatically matched to 1Y2O A:1-248
          1. region b:1-248 [122574] picpiclink
        3. 1wdz picpic
          1. region a:2-228 [120928] picpiclink
        4. 1wdz picpic
          automatically matched to 1WDZ A:2-228
          1. region b:2-228 [120929] picpiclink
  4. FCH domain [158645] (2)
    Pfam 00611; Fes/CIP4 homology domain
    1. Formin-binding protein 1, FNBP1 [158646]
      1. Human (Homo sapiens) [TaxId: 9606] [158647] (1)
        SQ Q96RU3 1-288
        1. 2efl picpic
          1. region a:1-288 [146816] picpiclink
    2. CDC42-interacting protein 4, CIP4 [158648]
      1. Human (Homo sapiens) [TaxId: 9606] [158649] (1)
        SQ Q15642 10-288
        1. 2efk picpic
          1. region a:10-288 [146815] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk