Structural Classification of Proteins
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Fold: BAR/IMD domain-like

6 helices, homodimer of 3-helical domains

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: BAR/IMD domain-like [116747]
    6 helices, homodimer of 3-helical domains

Superfamilies:

  1. BAR/IMD domain-like [103657] (4)
    core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends
    link to SUPERFAMILY database - Superfamily
    1. BAR domain [103658] (5)
      sensor of membrane curvature
      1. Amphiphysin [103659]
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [103660] (1)
          1. 1uru picpic
            1. chain a [99835] picpiclink
      2. Endophilin-1 [140699]
        SH3-containing GRB2-like protein 2
        1. Rat (Rattus norvegicus) [TaxId: 10116] [140700] (1)
          SQ Q62420 25-247
          UniProt sequence of Rat species, O35179, is a fragment that does not cover the entire domain
          1. 2c08 picpic
            1. region a:25-247 [129578] picpiclink
        2. Human (Homo sapiens) [TaxId: 9606] [140701] (6)
          SQ Q99962 11-247! SQ Q99962 26-247
          1. 2d4c picpic
            complexed with ca; mutant
            1. region a:11-247 [131246] picpiclink
          2. 2d4c picpic
            automatically matched to 2D4C A:11-247
            complexed with ca; mutant
            1. region b:11-247 [131247] picpiclink
          3. 2d4c picpic
            automatically matched to 2D4C A:11-247
            complexed with ca; mutant
            1. region c:11-247 [131248] picpiclink
          4. 2d4c picpic
            automatically matched to 2D4C A:11-247
            complexed with ca; mutant
            1. region d:12-247 [131249] picpiclink
          5. 1x04 picpic
            mutant
            1. region a:26-225 [121542] picpiclink
          6. 1x03 picpic
            1. region a:26-247 [121541] picpiclink
        3. Mouse (Mus musculus) [TaxId: 10090] [140702] (2)
          SQ Q62420 27-246
          1. 1zww picpic
            complexed with cd
            1. region a:27-246 [125750] picpiclink
          2. 1zww picpic
            automatically matched to 1ZWW A:27-246
            complexed with cd
            1. region b:28-246 [125751] picpiclink
      3. DCC-interacting protein 13-alpha, APPL1 [158643]
        1. Human (Homo sapiens) [TaxId: 9606] [158644] (1)
          SQ Q9UKG1 6-273
          1. 2elb picpicxref
            1. region a:6-273 [146895] picpiclink
    2. Arfaptin, Rac-binding fragment [64599] (1)
      1. Arfaptin, Rac-binding fragment [64600]
        active form is a dimer
        1. Human (Homo sapiens) [TaxId: 9606] [64601] (4)
          1. 1i4d picpicxref
            complexed with gdp, mg
            1. chain a [61682] picpiclink
            2. chain b [61683] picpiclink
          2. 1i4t picpicxref
            complexed with gnp, mg; mutant
            1. chain a [61729] picpiclink
            2. chain b [61730] picpiclink
          3. 1i4l picpicxref
            complexed with gdp, mg
            1. chain a [61718] picpiclink
            2. chain b [61719] picpiclink
          4. 1i49 picpic
            1. chain a [61679] picpiclink
            2. chain b [61680] picpiclink
    3. IMD domain [140703] (1)
      Pfam 08397
      1. BAP2/IRSp53 N-terminal domain [140704]
        1. Human (Homo sapiens) [TaxId: 9606] [140705] (4)
          SQ Q9UQB8 1-248! SQ Q9UQB8 2-228
          1. 1y2o picpic
            1. region a:1-248 [122573] picpiclink
          2. 1y2o picpic
            automatically matched to 1Y2O A:1-248
            1. region b:1-248 [122574] picpiclink
          3. 1wdz picpic
            1. region a:2-228 [120928] picpiclink
          4. 1wdz picpic
            automatically matched to 1WDZ A:2-228
            1. region b:2-228 [120929] picpiclink
    4. FCH domain [158645] (2)
      Pfam 00611; Fes/CIP4 homology domain
      1. Formin-binding protein 1, FNBP1 [158646]
        1. Human (Homo sapiens) [TaxId: 9606] [158647] (1)
          SQ Q96RU3 1-288
          1. 2efl picpic
            1. region a:1-288 [146816] picpiclink
      2. CDC42-interacting protein 4, CIP4 [158648]
        1. Human (Homo sapiens) [TaxId: 9606] [158649] (1)
          SQ Q15642 10-288
          1. 2efk picpic
            1. region a:10-288 [146815] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk