Structural Classification of Proteins

Superfamily: Defensin-like

: uperfamily

Lineage:

Root: scop
Class: Small proteins [56992]
Usually dominated by metal ligand, heme, and/or disulfide bridges
Fold: Defensin-like [57391]
Disulfide-rich fold, nearly all-beta
Superfamily: Defensin-like [57392]
uperfamily

Families:

Defensin [57393] (17)
1. Defensin HNP-3 [57394]
  1. Human (Homo sapiens) [TaxId: 9606] [57395] (1)
    1. 1dfn
      1. chain a [44570]
      2. chain b [44571]
2. Beta-defensin, BD [63384]
  1. Human (Homo sapiens), HBD1 [TaxId: 9606] [64551] (4)
    1. 1ijv
      complexed with br, k, so4
      1. chain a [66169]
      2. chain b [66170]
    2. 1iju
      complexed with gol, so4
      1. chain a [66165]
      2. chain b [66166]
      3. chain c [66167]
      4. chain d [66168]
    3. 1e4s
      1. chain a [59229]
    4. 1kj5
      1. chain a [72579]
  2. Human (Homo sapiens), HBD2 [TaxId: 9606] [63385] (4)
    1. 1fd3
      complexed with so4
      1. chain a [44572]
      2. chain b [44573]
      3. chain c [44574]
      4. chain d [44575]
    2. 1fd4
      complexed with so4
      1. chain a [44576]
      2. chain b [44577]
      3. chain c [44578]
      4. chain d [44579]
      5. chain e [44580]
      6. chain f [44581]
      7. chain g [44582]
      8. chain h [44583]
      9. chain i [44584]
      10. chain j [44585]
      11. chain k [44586]
      12. chain l [44587]
      13. chain m [44588]
      14. chain n [44589]
      15. chain o [44590]
      16. chain p [44591]
    3. 1e4q
      1. chain a [59227]
    4. 1fqq
      1. chain a [59990]
  3. Human (Homo sapiens), HBD3 [TaxId: 9606] [75672] (1)
    1. 1kj6
      1. chain a [72580]
  4. Mouse (Mus musculus), MBD5 [TaxId: 10090] [64552] (1)
    1. 1e4t
      1. chain a [59230]
  5. Mouse (Mus musculus), MBD6 [TaxId: 10090] [64553] (1)
    1. 1e4r
      1. chain a [59228]
  6. Cow (Bos taurus), BD12 [TaxId: 9913] [63386] (1)
    1. 1bnb
      1. chain a [44592]
  7. King penguin (Aptenodytes patagonicus), spheniscin-2 [TaxId: 9234] [103570] (1)
    1. 1ut3
      1. chain a [99899]
3. Alpha-defensin rk-1 [64554]
  1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [64555] (1)
    1. 1ews
      1. chain a [59534]
4. Defensin-like peptide, DLP [57400]
  1. Duckbilled platypus (Ornithorhynchus anatinus), DLP-1 [TaxId: 9258] [57401] (1)
    1. 1b8w
      1. chain a [44593]
  2. Duckbilled platypus (Ornithorhynchus anatinus), DLP-2 [TaxId: 9258] [57402] (3)
    1. 1zue
      automatically matched to d1d6ba_
      complexed with med
      1. region a:1-42 [125670]
    2. 1zuf
      automatically matched to d1d6ba_
      1. region a:1-42 [125671]
    3. 1d6b
      1. chain a [44594]
5. BDs-I defensin [57403]
  1. Sea anemone (Anemonia sulcata) [TaxId: 6108] [57404] (2)
    1. 2bds
      1. chain a [44595]
    2. 1bds
      1. chain a [44596]
6. Sea anemone neurotoxin-1 [57405]
  1. Sea anemone (Stichodactyla helianthus) [TaxId: 6123] [57406] (3)
    1. 2sh1
      1. chain a [44598]
    2. 1sh1
      1. chain a [44597]
    3. 1shi
      complexed with nh2
      1. chain a [44599]
7. Sea anemone toxin IA [57407]
  1. Sea anemone (Anemonia sulcata) [TaxId: 6108] [57408] (1)
    1. 1atx
      1. chain a [44600]
8. Anthopleurin-A [57409]
  1. Giant green sea anemone (Anthopleura xanthogrammica) [TaxId: 6112] [57410] (1)
    1. 1ahl
      1. chain a [44601]
9. Anthopleurin-B [57411]
  1. Giant green sea anemone (Anthopleura xanthogrammica) [TaxId: 6112] [57412] (1)
    1. 1apf
      1. chain a [44602]
10. Defensin-related cryptdin 4 [118245]
  1. Mouse (Mus musculus) [TaxId: 10090] [118246] (2)
    SQ P28311 61-92
    1. 1tv0
      1. chain a [112671]
    2. 2gw9
      automatically matched to d1tv0a_
      1. region a:1-32 [135801]
Myotoxin [90157] (1)
structurally similar to beta-defensin
1. Crotamine [90158]
  1. South american rattlesnake (Crotalus durissus terrificus) [TaxId: 8732] [90159] (2)
    1. 1h5o
      1. chain a [83484]
    2. 1z99
      automatically matched to d1h5oa_
      1. region a:1-42 [124746]
Tick carboxypeptidase inhibitor-like [161135] (1)
1. Carboxypeptidase inhibitor [161136]
  consists of two structurally similar to beta-defensin domains
  1. Tick (Rhipicephalus bursa) [TaxId: 67831] [161137] (8)
    SQ Q5EPH2 23-59! SQ Q5EPH2 60-96
    1. 3d4u
      automatically matched to 1ZLH B:1-37
      complexed with act, so4, zn
      1. region b:1-37 [157300]
    2. 3d4u
      automatically matched to 1ZLH B:38-74
      complexed with act, so4, zn
      1. region b:38-74 [157301]
    3. 1zlh
      complexed with zn
      1. region b:1-37 [144742]
    4. 1zlh
      complexed with zn
      1. region b:38-74 [144743]
    5. 1zli
      automatically matched to 1ZLH B:1-37
      complexed with zn
      1. region b:1-37 [144744]
    6. 1zli
      automatically matched to 1ZLH B:38-74
      complexed with zn
      1. region b:38-74 [144745]
    7. 2jto
      automatically matched to 1ZLH B:1-37
      1. region a:1-37 [148203]
    8. 2jto
      automatically matched to 1ZLH B:38-74
      1. region a:38-74 [148204]