Structural Classification of Proteins
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Family: Snake venom toxins

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Snake toxin-like [57301]
    disulfide-rich fold: nearly all-beta
  4. Superfamily: Snake toxin-like [57302]
    link to SUPERFAMILY database - Superfamily
  5. Family: Snake venom toxins [57303]

Protein Domains:

  1. Erabutoxin B (also neurotoxin B) [57304]
    1. Sea snake (Laticauda semifasciata) [TaxId: 8631] [57305] (7)
      1. 3ebx picpic
        complexed with so4
        1. chain a [44389] picpiclink
      2. 1qkd picpic
        1. chain a [44390] picpiclink
        2. chain b [44391] picpiclink
      3. 1qke picpic
        complexed with so4
        1. chain a [44392] picpiclink
      4. 6ebx picpic
        complexed with scn
        1. chain a [44393] picpiclink
        2. chain b [44394] picpiclink
      5. 1nxb picpic
        1. chain a [44395] picpiclink
      6. 1era picpic
        1. chain a [44397] picpiclink
      7. 1fra picpic
        1. chain a [44396] picpiclink
  2. gamma-Cardiotoxin [57306]
    1. Snake (Naja nigricollis) [TaxId: 8654] [57307] (3)
      1. 1tgx picpic
        complexed with cl
        1. chain a [44398] picpiclink
        2. chain b [44399] picpiclink
        3. chain c [44400] picpiclink
      2. 1cxn picpic
        1. chain a [44401] picpiclink
      3. 1cxo picpic
        1. chain a [44402] picpiclink
  3. Fasciculin [57308]
    different isoforms
    1. Green mamba (Dendroaspis angusticeps) [TaxId: 8618] [57309] (8)
      1. 1fas picpic
        1. chain a [44403] picpiclink
      2. 1fsc picpic
        complexed with o s
        1. chain a [44404] picpiclink
      3. 1ku6 picpicxref
        complexed with edo, nag
        1. chain b [91038] picpiclink
      4. 1f8u picpicxref
        complexed with nag; mutant
        1. chain b [44406] picpiclink
      5. 1b41 picpicxref
        complexed with fuc, nag; mutant
        1. chain b [44409] picpiclink
      6. 1fss picpicxref
        complexed with nag, zn
        1. chain b [44408] picpiclink
      7. 1mah picpicxref
        complexed with nag
        1. chain f [44407] picpiclink
      8. 1qm7 picpic
        engineered chimera with alpha-toxin
        1. chain a [44405] picpiclink
  4. Muscarinic toxin [90152]
    acetylcholine receptor binding protein
    1. Green mamba (Dendroaspis angusticeps) [TaxId: 8618] [90153] (1)
      1. 1ff4 picpic
        complexed with sul
        1. chain a [83251] picpiclink
  5. Erabutoxin A [57310]
    1. Broad-banded blue sea snake (Laticauda semifasciata) [TaxId: 8631] [57311] (3)
      1. 3era picpic
        complexed with scn; mutant
        1. chain a [44410] picpiclink
        2. chain b [44411] picpiclink
      2. 2era picpic
        mutant
        1. chain a [44412] picpiclink
      3. 5ebx picpic
        complexed with so4
        1. chain a [44413] picpiclink
  6. Neurotoxin I [57312]
    1. Snake (Naja naja oxiana) [TaxId: 8657] [57313] (2)
      SQ P01382
      1. 1ntn picpic
        1. chain a [44414] picpiclink
      2. 1w6b picpic
        1. chain a [114268] picpiclink
  7. Cardiotoxin V4II (Toxin III) [57314]
    1. Naja mossambica mossambica [TaxId: 196380] [57315] (1)
      1. 1cdt picpic
        complexed with po4
        1. chain a [44415] picpiclink
        2. chain b [44416] picpiclink
  8. Cardiotoxin V [57316]
    1. Taiwan cobra (Naja naja atra) [TaxId: 8656] [57317] (2)
      1. 1kxi picpic
        1. chain a [44417] picpiclink
        2. chain b [44418] picpiclink
      2. 1cvo picpic
        1. chain a [44419] picpiclink
  9. alpha-Cobratoxin [57318]
    1. Cobra (Naja siamensis) [TaxId: 84476] [57319] (7)
      1. 2ctx picpic
        1. chain a [44420] picpiclink
      2. 1ctx picpic
        1. chain a [44421] picpiclink
      3. 1yi5 picpicxrefxrefxrefxrefxref
        automatically matched to d1ctx__
        1. region f:1-68 [123261] picpiclink
      4. 1yi5 picpicxrefxrefxrefxrefxref
        automatically matched to d1ctx__
        1. region g:1-68 [123262] picpiclink
      5. 1yi5 picpicxrefxrefxrefxrefxref
        automatically matched to d1ctx__
        1. region h:1-68 [123263] picpiclink
      6. 1yi5 picpicxrefxrefxrefxrefxref
        automatically matched to d1ctx__
        1. region i:1-67 [123264] picpiclink
      7. 1yi5 picpicxrefxrefxrefxrefxref
        automatically matched to d1ctx__
        1. region j:1-68 [123265] picpiclink
    2. Monocled cobra (Naja naja kaouthia) [TaxId: 8649] [82899] (2)
      identical sequence to the Naja naja siamensis toxin
      1. 1lxg picpic
        complexed to a cognate peptide, chain B
        1. chain a [78294] picpiclink
      2. 1lxh picpic
        complexed to a cognate peptide, chain B
        1. chain a [78295] picpiclink
  10. Long neurotoxin 1 (component LSIII) [57320]
    1. Sea snake (Laticauda semifasciata) [TaxId: 8631] [57321] (1)
      1. 1lsi picpic
        1. chain a [44422] picpiclink
  11. FS2 toxin [57322]
    1. Black mamba (Dendroaspis polylepis polylepis) [TaxId: 8620] [57323] (1)
      1. 1tfs picpic
        1. chain a [44423] picpiclink
  12. Bungarotoxin [57324]
    1. Many-banded krait (Bungarus multicinctus), Alpha-bungarotoxin [TaxId: 8616] [57325] (22)
      1. 1hc9 picpic
        complexed with high affinity peptide
        complexed with ido
        1. chain a [65786] picpiclink
        2. chain b [65787] picpiclink
      2. 2qc1 picpic
        automatically matched to d1hc9a_
        complexed with man, nag; mutant
        1. region a:1-74 [150650] picpiclink
      3. 2abx picpic
        1. chain a [44424] picpiclink
        2. chain b [44425] picpiclink
      4. 1kfh picpic
        1. chain a [72412] picpiclink
      5. 1ikc picpic
        complexed with a mimotope of the nicotinic acetylcholine receptor, chain B
        1. chain a [62526] picpiclink
      6. 1abt picpic
        1. chain a [44426] picpiclink
      7. 1jbd picpic
        complexed with a mimotope of the nicotinic acetylcholine receptor, chain B
        1. chain a [62844] picpiclink
      8. 1haj picpic
        complexed with a high affinity 13-mer peptide
        1. chain a [60878] picpiclink
      9. 1ljz picpic
        complexed with an ACHR peptide, chain B
        1. chain a [73947] picpiclink
      10. 1haa picpic
        complexed with a high affinity 13-mer peptide
        1. chain a [60877] picpiclink
      11. 1idi picpic
        1. chain a [62298] picpiclink
      12. 1bxp picpic
        1. chain a [44428] picpiclink
      13. 1hoy picpic
        complexed with a mimotope of the nicotinic acetylcholine receptor, chain B
        1. chain a [44429] picpiclink
      14. 1kc4 picpic
        complex with the principal binding sequence on the alpha7 subunit of a neuronal nicotinic acetylcholine receptor, chain B
        1. chain a [72293] picpiclink
      15. 2btx picpic
        1. chain a [44430] picpiclink
      16. 1idh picpic
        complexed to an 18mer cognate peptide
        1. chain a [62297] picpiclink
      17. 1idl picpic
        1. chain a [62299] picpiclink
      18. 1rgj picpic
        complexed with a mimotope of the nicotinic acetylcholine receptor, chain B
        1. chain a [97439] picpiclink
      19. 1l4w picpic
        complexed with an ACHR peptide, chain B
        1. chain a [73570] picpiclink
      20. 1idg picpic
        complexed to an 18mer cognate peptide
        1. chain a [62296] picpiclink
      21. 1kl8 picpic
        complex with the principal binding sequence on the alpha7 subunit of a neuronal nicotinic acetylcholine receptor, chain B
        1. chain a [72680] picpiclink
      22. 1ik8 picpic
        1. chain a [62525] picpiclink
    2. Many-banded krait (Bungarus multicinctus), kappa-bungarotoxin [TaxId: 8616] [57326] (1)
      1. 1kba picpic
        1. chain a [44431] picpiclink
        2. chain b [44432] picpiclink
    3. Many-banded krait (Bungarus multicinctus), neuronal bungarotoxin [TaxId: 8616] [57327] (1)
      1. 2nbt picpic
        1. chain a [44433] picpiclink
        2. chain b [44434] picpiclink
    4. Many-banded krait (Bungarus multicinctus), gamma-bungarotoxin [TaxId: 8616] [111403] (1)
      SQ Q9YGJ0 22-89
      1. 1mr6 picpic
        1. chain a [103847] picpiclink
  13. Bucandin [57328]
    1. Malayan krait (Bungarus candidus) [TaxId: 92438] [57329] (2)
      1. 1f94 picpic
        1. chain a [44435] picpiclink
      2. 1ijc picpic
        1. chain a [66154] picpiclink
  14. Cardiotoxin CTXI [57330]
    1. Taiwan cobra (Naja naja atra) [TaxId: 8656] [57331] (1)
      1. 2cdx picpic
        1. chain a [44436] picpiclink
  15. Cardiotoxin CTX IIB [57332]
    1. Naja mossambica mossambica [TaxId: 196380] [57333] (1)
      1. 2ccx picpic
        1. chain a [44437] picpiclink
  16. Cardiotoxin II [57334]
    1. Taiwan cobra (Naja naja atra) [TaxId: 8656] [57335] (3)
      1. 1chv picpic
        1. chain s [44438] picpiclink
      2. 1crf picpic
        1. chain a [44439] picpiclink
      3. 1cre picpic
        1. chain a [44440] picpiclink
    2. Central asian cobra (Naja naja oxiana) [TaxId: 8657] [57336] (3)
      1. 1cb9 picpic
        1. chain a [44442] picpiclink
      2. 1ccq picpic
        1. chain a [44443] picpiclink
      3. 1ffj picpic
        solution structure in dpc-micelle
        1. chain a [44441] picpiclink
  17. Cardiotoxin III [57337]
    1. Taiwan cobra (Naja naja atra) [TaxId: 8656] [57338] (7)
      SQ P60301 22-81
      1. 1h0j picpic
        complexed with sds
        1. chain a [83432] picpiclink
        2. chain b [83433] picpiclink
        3. chain c [83434] picpiclink
      2. 2bhi picpic
        automatically matched to d1h0ja_
        complexed with c10, sft
        1. region a:1-60 [128531] picpiclink
      3. 2bhi picpic
        automatically matched to d1h0ja_
        complexed with c10, sft
        1. region b:1-60 [128532] picpiclink
      4. 1xt3 picpic
        complexed with cit, idu, sgn
        1. chain a [116010] picpiclink
        2. chain b [116011] picpiclink
      5. 1i02 picpic
        1. chain a [44444] picpiclink
      6. 2crs picpic
        1. chain a [44445] picpiclink
      7. 2crt picpic
        1. chain a [44446] picpiclink
  18. Cardiotoxin IV [57339]
    1. Taiwan cobra (Naja naja atra) [TaxId: 8656] [57340] (2)
      1. 1kbs picpic
        1. chain a [44447] picpiclink
      2. 1kbt picpic
        1. chain a [44448] picpiclink
  19. Cobrotoxin II (ct2) [57341]
    1. Taiwan cobra (Naja naja atra) [TaxId: 8656] [57342] (3)
      SQ P60770 22-83
      1. 1v6p picpic
        complexed with cl, cu, eoh, na
        1. chain a [113548] picpiclink
        2. chain b [113549] picpiclink
      2. 1coe picpic
        1. chain a [44450] picpiclink
      3. 1cod picpic
        1. chain a [44449] picpiclink
    2. Monocled cobra (Naja kaouthia) [TaxId: 8649] [57343] (1)
      1. 1g6m picpic
        1. chain a [44451] picpiclink
  20. alpha-Toxin [57344]
    1. Spitting cobra (Naja nigricollis) [TaxId: 8654] [57345] (2)
      1. 1iq9 picpic
        complexed with so4
        1. chain a [90669] picpiclink
      2. 1nea picpic
        1. chain a [44452] picpiclink
    2. Black mamba (Dendroaspis polylepis polylepis) [TaxId: 8620] [57346] (1)
      1. 1ntx picpic
        1. chain a [44453] picpiclink
  21. Neurotoxin II (Nt2, cobrotoxin B) [57347]
    1. Central asian cobra (Naja naja oxiana) [TaxId: 8657] [57348] (1)
      1. 1nor picpic
        1. chain a [44454] picpiclink
    2. Monocled cobra (Naja kaouthia) [TaxId: 8649] [64550] (1)
      1. 1je9 picpic
        1. chain a [62911] picpiclink
    3. Chinese cobra (Naja atra) [TaxId: 8656] [103569] (2)
      SQ P80958 22-82
      1. 1vb0 picpic
        complexed with so4, trs
        1. chain a [113601] picpiclink
      2. 1onj picpic
        complexed with so4
        1. chain a [93358] picpiclink
  22. Toxin B (long neurotoxin) [57349]
    1. King cobra (Ophiophagus hannah) [TaxId: 8665] [57350] (2)
      1. 1txb picpic
        1. chain a [44455] picpiclink
      2. 1txa picpic
        1. chain a [44456] picpiclink
  23. Candoxin [69949]
    1. Malayan krait (Bungarus candidus) [TaxId: 92438] [69950] (1)
      1. 1jgk picpic
        1. chain a [66678] picpiclink
  24. Bucain [111404]
    1. Malaysian krait (Bungarus candidus) [TaxId: 92438] [111405] (3)
      SQ P83346
      1. 2h8u picpic
        automatically matched to d1vyca_
        1. region a:1-65 [136246] picpiclink
      2. 2h8u picpic
        automatically matched to d1vyca_
        1. region b:1-65 [136247] picpiclink
      3. 1vyc picpic
        1. chain a [108899] picpiclink
  25. Irditoxin subunit A [144103]
    1. Brown tree snake (Boiga irregularis) [TaxId: 92519] [144104] (1)
      SQ A0S864 35-109
      1. 2h7z picpicxref
        1. region a:1-75 [136231] picpiclink
  26. Irditoxin subunit B [144105]
    1. Brown tree snake (Boiga irregularis) [TaxId: 92519] [144106] (1)
      SQ A0S865 35-111
      1. 2h7z picpicxref
        1. region b:1-77 [136232] picpiclink
  27. Denmotoxin [144107]
    1. Mangrove snake (Boiga dendrophila) [TaxId: 46286] [144108] (2)
      SQ Q06ZW0 33-111
      1. 2h5f picpic
        complexed with k, na, po4
        1. region a:3-77 [136147] picpiclink
      2. 2h5f picpic
        automatically matched to 2H5F A:3-77
        complexed with k, na, po4
        1. region b:4-77 [136148] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk