Structural Classification of Proteins
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Family: RING finger domain, C3HC4

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: RING/U-box [57849]
    dimetal(zinc)-bound alpha+beta motif; structurally diverse
  4. Superfamily: RING/U-box [57850]
    link to SUPERFAMILY database - Superfamily
  5. Family: RING finger domain, C3HC4 [57851]

Protein Domains:

  1. CBL [57852]
    1. Human (Homo sapiens) [TaxId: 9606] [57853] (1)
      1. 1fbv picpicxrefxrefxrefxref
        complexed with so4, zn
        1. region a:356-434 [45321] picpiclink
  2. V(D)J recombination activating protein 1 (RAG1), dimerization domain [57854]
    1. Mouse (Mus musculus) [TaxId: 10090] [57855] (1)
      1. 1rmd picpicxref
        include dimerization helices
        complexed with zn
        1. region a:1-86 [45322] picpiclink
  3. Immediate early protein, IEEHV [57856]
    1. Equine herpesvirus 1 [TaxId: 10326] [57857] (1)
      1. 1chc picpic
        complexed with zn
        1. chain a [45323] picpiclink
  4. Acute promyelocytic leukaemia proto-oncoprotein PML [57858]
    1. Human (Homo sapiens) [TaxId: 9606] [57859] (1)
      1. 1bor picpic
        complexed with zn
        1. chain a [45324] picpiclink
  5. TFIIH Mat1 subunit [57860]
    1. Human (Homo sapiens) [TaxId: 9606] [57861] (1)
      1. 1g25 picpic
        complexed with zn
        1. chain a [45325] picpiclink
  6. Not-4 N-terminal RING finger domain [64579]
    1. Human (Homo sapiens) [TaxId: 9606] [64580] (2)
      1. 1ur6 picpicxref
        complexed with zn
        1. chain b [99812] picpiclink
      2. 1e4u picpic
        complexed with zn
        1. chain a [59231] picpiclink
  7. brca1 RING domain [69968]
    1. Human (Homo sapiens) [TaxId: 9606] [69969] (1)
      1. 1jm7 picpicxref
        heterodimer with bard1 RING domain
        complexed with zn
        1. chain a [66880] picpiclink
  8. bard1 RING domain [69970]
    1. Human (Homo sapiens) [TaxId: 9606] [69971] (1)
      1. 1jm7 picpicxref
        heterodimer with brca1 RING domain
        complexed with zn
        1. chain b [66881] picpiclink
  9. RIGG-box protein 1 (RBX1) of SCF ubiquitin ligase complex [75693]
    1. Human (Homo sapiens) [TaxId: 9606] [75694] (7)
      SQ P62877 19-106
      1. 3dpl picpic
        automatically matched to d1ldjb_
        complexed with zn; mutant
        1. region r:19-106 [157824] picpiclink
      2. 3dqv picpicxref
        automatically matched to d1ldjb_
        complexed with zn; mutant
        1. region r:20-105 [157828] picpiclink
      3. 3dqv picpicxref
        automatically matched to d1ldjb_
        complexed with zn; mutant
        1. region y:19-105 [157829] picpiclink
      4. 1ldj picpicxrefxrefxref
        complexed with zn
        1. chain b [73850] picpiclink
      5. 1u6g picpicxrefxrefxrefxref
        complexed with zn
        1. chain b [113065] picpiclink
      6. 2hye picpicxrefxrefxref
        automatically matched to d1ldjb_
        complexed with zn
        1. region d:19-106 [136879] picpiclink
      7. 1ldk picpicxrefxrefxrefxrefxrefxref
        complexed with zn
        1. chain c [73854] picpiclink
  10. EL5 RING-H2 domain [90220]
    binding domain for E2 ubiquitin ligase
    1. Rice (Oryza sativa) [TaxId: 4530] [90221] (1)
      1. 1iym picpic
        complexed with zn
        1. chain a [83806] picpiclink
  11. Deltex protein 2 RING-H2 domain [111457]
    1. Mouse (Mus musculus) [TaxId: 10090] [111458] (1)
      SQ Q8R3P2 389-489
      1. 1v87 picpic
        Structural genomics target
        C-terminal RING domain; one zinc ion-bound structure adopts a different fold; misfolded conformation (?)
        complexed with zn
        1. chain a [108422] picpiclink
  12. Ariadne-1 protein homolog [111459]
    1. Human (Homo sapiens) [TaxId: 9606] [111460] (1)
      SQ Q9Y4X5 336-394
      1. 1wd2 picpic
        complexed with zn
        1. chain a [109232] picpiclink
  13. Cellulose synthase A catalytic subunit 7, IRX3 [118294]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [118295] (1)
      SQ Q9SWW6 26-95
      1. 1weo picpic
        Structural genomics target
        complexed with zn
        1. chain a [114561] picpiclink
  14. UbcM4-interacting protein 4 (KIAA0161) [118296]
    1. Human (Homo sapiens) [TaxId: 9606] [118297] (1)
      1. 1wim picpic
        Structural genomics target; contains extra C-terminal IBR region
        complexed with zn
        1. chain a [114677] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk