Structural Classification of Proteins

Superfamily: RING/U-box

: uperfamily

Lineage:

Root: scop
Class: Small proteins [56992]
Usually dominated by metal ligand, heme, and/or disulfide bridges
Fold: RING/U-box [57849]
dimetal(zinc)-bound alpha+beta motif; structurally diverse
Superfamily: RING/U-box [57850]
uperfamily

Families:

RING finger domain, C3HC4 [57851] (14)
1. CBL [57852]
  1. Human (Homo sapiens) [TaxId: 9606] [57853] (1)
2. V(D)J recombination activating protein 1 (RAG1), dimerization domain [57854]
  1. Mouse (Mus musculus) [TaxId: 10090] [57855] (1)
3. Immediate early protein, IEEHV [57856]
  1. Equine herpesvirus 1 [TaxId: 10326] [57857] (1)
4. Acute promyelocytic leukaemia proto-oncoprotein PML [57858]
  1. Human (Homo sapiens) [TaxId: 9606] [57859] (1)
5. TFIIH Mat1 subunit [57860]
  1. Human (Homo sapiens) [TaxId: 9606] [57861] (1)
6. Not-4 N-terminal RING finger domain [64579]
  1. Human (Homo sapiens) [TaxId: 9606] [64580] (2)
7. brca1 RING domain [69968]
  1. Human (Homo sapiens) [TaxId: 9606] [69969] (1)
8. bard1 RING domain [69970]
  1. Human (Homo sapiens) [TaxId: 9606] [69971] (1)
9. RIGG-box protein 1 (RBX1) of SCF ubiquitin ligase complex [75693]
  1. Human (Homo sapiens) [TaxId: 9606] [75694] (7)
    SQ P62877 19-106
10. EL5 RING-H2 domain [90220]
  binding domain for E2 ubiquitin ligase
  1. Rice (Oryza sativa) [TaxId: 4530] [90221] (1)
11. Deltex protein 2 RING-H2 domain [111457]
  1. Mouse (Mus musculus) [TaxId: 10090] [111458] (1)
    SQ Q8R3P2 389-489
12. Ariadne-1 protein homolog [111459]
  1. Human (Homo sapiens) [TaxId: 9606] [111460] (1)
    SQ Q9Y4X5 336-394
13. Cellulose synthase A catalytic subunit 7, IRX3 [118294]
  1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [118295] (1)
    SQ Q9SWW6 26-95
14. UbcM4-interacting protein 4 (KIAA0161) [118296]
  1. Human (Homo sapiens) [TaxId: 9606] [118297] (1)
U-box [90222] (4)
Associated with multi-ubiquitination; lacks the RING-domain metal ion-binding residues
1. Pre-mRNA splicing factor Prp19 [90223]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [90224] (7)
2. E3 ubiquitin ligase PUB14 [111461]
  Armadillo repeat containing protein
  1. Thale-cress (Arabidopsis thaliana) [TaxId: 3702] [111462] (1)
    SQ Q8VZ40 249-321
3. Ubiquitin conjugation factor E4A [118298]
  1. Human (Homo sapiens) [TaxId: 9606] [118299] (1)
    SQ Q14139 977-1061
4. STIP1 homology and U box-containing protein 1, STUB1 [144224]
  1. Mouse (Mus musculus) [TaxId: 10090] [144225] (8)
    SQ Q9WUD1 225-304! SQ Q9WUD1 227-301
Variant RING domain [118300] (2)
1. IE1B protein (ORF K3), N-terminal domain [118301]
  1. Kaposi's sarcoma-associated herpesvirus, KSHV, HHV8 [TaxId: 37296] [118302] (1)
    SQ P90495 1-60
2. Protein c14orf4 (KIAA1865) [144226]
  1. Human (Homo sapiens) [TaxId: 9606] [144227] (1)
    SQ Q9H1B7 705-786
IBR domain [144228] (1)
Smart 00647; RING-associated domain
1. Ring finger protein 31 [144229]
  1. Human (Homo sapiens) [TaxId: 9606] [144230] (1)
    SQ Q96EP0 779-851
Zf-UBP [161204] (3)
Pfam 02148
1. Hypothetical protein RPA1320 [161205]
  1. Rhodopseudomonas palustris [TaxId: 1076] [161206] (1)
    SQ Q6NA67 1-102
2. Ubiquitin carboxyl-terminal hydrolase 5, UBP5 [161207]
  1. Human (Homo sapiens) [TaxId: 9606] [161208] (4)
    SQ P45974 169-285
3. Ubiquitin carboxyl-terminal hydrolase 33, UBP33 [161209]
  1. Human (Homo sapiens) [TaxId: 9606] [161210] (1)
    SQ Q8TEY7 36-130
ZZ domain [161211] (3)
Pfam 00569
1. CREB-binding protein, CBP [161212]
  1. Mouse (Mus musculus) [TaxId: 10090] [161213] (1)
    SQ P45481 1700-1751
2. Zinc finger ZZ-type-containing protein 2 [161214]
  1. Human (Homo sapiens) [TaxId: 9606] [161215] (1)
    SQ Q8NEG5 208-292
3. Zinc finger ZZ-type-containing protein 3, ZZZ3 [161216]
  1. Human (Homo sapiens) [TaxId: 9606] [161217] (1)
    SQ Q8IYR1 313-381