Structural Classification of Proteins
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Superfamily: Hairpin loop containing domain-like

the middle part is structurally similar to some knottins and defensins but differs in the disulfide pattern
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Hairpin loop containing domain-like [57413]
    alpha+beta fold with two crossing loops
  4. Superfamily: Hairpin loop containing domain-like [57414]
    the middle part is structurally similar to some knottins and defensins but differs in the disulfide pattern
    link to SUPERFAMILY database - Superfamily

Families:

  1. Hairpin loop containing domain [57415] (1)
    1. Hepatocyte growth factor [57416]
      heparin-binding domain
      1. Human (Homo sapiens) [TaxId: 9606] [57417] (8)
        1. 2qj2 picpicxrefxref
          automatically matched to d2hgfa_
          complexed with so4
          1. region a:36-126 [150817] picpiclink
        2. 2qj2 picpicxrefxref
          automatically matched to d2hgfa_
          complexed with so4
          1. region b:1036-1126 [150819] picpiclink
        3. 1bht picpicxref
          complexed with epe, so4
          1. region a:35-126 [44603] picpiclink
          2. region b:336-426 [44604] picpiclink
        4. 1gmn picpicxref
          complexed with epe, ids, sgn; mutant
          1. region a:38-125 [65315] picpiclink
          2. region b:42-125 [65317] picpiclink
        5. 1gp9 picpicxref
          complexed with epe
          1. region a:39-125 [65442] picpiclink
          2. region b:39-125 [65444] picpiclink
          3. region c:38-125 [65446] picpiclink
          4. region d:39-125 [65448] picpiclink
        6. 1nk1 picpicxref
          mutant
          1. region a:38-125 [44605] picpiclink
          2. region b:38-125 [44606] picpiclink
        7. 1gmo picpicxref
          complexed with epe, ids, sgn, so4; mutant
          1. region a:37-125 [65319] picpiclink
          2. region b:37-125 [65321] picpiclink
          3. region c:37-125 [65323] picpiclink
          4. region d:37-125 [65325] picpiclink
          5. region e:37-125 [65327] picpiclink
          6. region f:37-125 [65329] picpiclink
          7. region g:38-125 [65331] picpiclink
          8. region h:38-125 [65333] picpiclink
        8. 2hgf picpic
          1. chain a [44607] picpiclink
  2. Anti-platelet protein [64556] (1)
    1. Anti-platelet protein [64557]
      1. Leech (Haementeria officinalis) [TaxId: 6410] [64558] (1)
        1. 1i8n picpic
          complexed with rop
          1. chain a [61976] picpiclink
          2. chain b [61977] picpiclink
          3. chain c [61978] picpiclink
  3. Pan module (APPLE domain) [82901] (1)
    probable carbohydrate-binding function
    1. Pan module from microneme protein 5 (MIC-5) [82902]
      1. Eimeria tenella [TaxId: 5802] [82903] (1)
        1. 1hky picpic
          1. chain a [76714] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk