Structural Classification of Proteins
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Fold: Hairpin loop containing domain-like

alpha+beta fold with two crossing loops

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Hairpin loop containing domain-like [57413]
    alpha+beta fold with two crossing loops

Superfamilies:

  1. Hairpin loop containing domain-like [57414] (3)
    the middle part is structurally similar to some knottins and defensins but differs in the disulfide pattern
    link to SUPERFAMILY database - Superfamily
    1. Hairpin loop containing domain [57415] (1)
      1. Hepatocyte growth factor [57416]
        heparin-binding domain
        1. Human (Homo sapiens) [TaxId: 9606] [57417] (8)
          1. 2qj2 picpicxrefxref
            automatically matched to d2hgfa_
            complexed with so4
            1. region a:36-126 [150817] picpiclink
          2. 2qj2 picpicxrefxref
            automatically matched to d2hgfa_
            complexed with so4
            1. region b:1036-1126 [150819] picpiclink
          3. 1bht picpicxref
            complexed with epe, so4
            1. region a:35-126 [44603] picpiclink
            2. region b:336-426 [44604] picpiclink
          4. 1gmn picpicxref
            complexed with epe, ids, sgn; mutant
            1. region a:38-125 [65315] picpiclink
            2. region b:42-125 [65317] picpiclink
          5. 1gp9 picpicxref
            complexed with epe
            1. region a:39-125 [65442] picpiclink
            2. region b:39-125 [65444] picpiclink
            3. region c:38-125 [65446] picpiclink
            4. region d:39-125 [65448] picpiclink
          6. 1nk1 picpicxref
            mutant
            1. region a:38-125 [44605] picpiclink
            2. region b:38-125 [44606] picpiclink
          7. 1gmo picpicxref
            complexed with epe, ids, sgn, so4; mutant
            1. region a:37-125 [65319] picpiclink
            2. region b:37-125 [65321] picpiclink
            3. region c:37-125 [65323] picpiclink
            4. region d:37-125 [65325] picpiclink
            5. region e:37-125 [65327] picpiclink
            6. region f:37-125 [65329] picpiclink
            7. region g:38-125 [65331] picpiclink
            8. region h:38-125 [65333] picpiclink
          8. 2hgf picpic
            1. chain a [44607] picpiclink
    2. Anti-platelet protein [64556] (1)
      1. Anti-platelet protein [64557]
        1. Leech (Haementeria officinalis) [TaxId: 6410] [64558] (1)
          1. 1i8n picpic
            complexed with rop
            1. chain a [61976] picpiclink
            2. chain b [61977] picpiclink
            3. chain c [61978] picpiclink
    3. Pan module (APPLE domain) [82901] (1)
      probable carbohydrate-binding function
      1. Pan module from microneme protein 5 (MIC-5) [82902]
        1. Eimeria tenella [TaxId: 5802] [82903] (1)
          1. 1hky picpic
            1. chain a [76714] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk