Structural Classification of Proteins
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Fold: Type II DNA topoisomerase

4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

Lineage:

  1. Root: scop
  2. Class: Multi-domain proteins (alpha and beta) [56572]
    Folds consisting of two or more domains belonging to different classes
  3. Fold: Type II DNA topoisomerase [56718]
    4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

Superfamilies:

  1. Type II DNA topoisomerase [56719] (1)
    link to SUPERFAMILY database - Superfamily
    1. Type II DNA topoisomerase [56720] (2)
      domain 2 contains the catalytic tyrosine residue
      1. DNA topoisomerase II, C-terminal fragment (residues 410-1202) [56721]
        the N-terminal fragment is homologous to known structure of DNA gyrase B
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [56722] (3)
          1. 1bjt picpic
            1. chain a [43249] picpiclink
          2. 2rgr picpic
            automatically matched to d1bjta_
            complexed with mg
            1. region a:419-1177 [152021] picpiclink
          3. 1bgw picpic
            1. chain a [43250] picpiclink
      2. DNA Gyrase A [56723]
        1. Escherichia coli [TaxId: 562] [56724] (3)
          1. 1ab4 picpic
            fragment lacking toprim domain 1
            1. chain a [43251] picpiclink
          2. 1x75 picpicxrefxref
            CcdB-interacting subdomain only
            1. region a:363-494 [144576] picpiclink
          3. 1x75 picpicxrefxref
            automatically matched to 1X75 A:363-494
            1. region b:363-494 [144577] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk