Structural Classification of Proteins
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Superfamily: PLP-dependent transferases

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: PLP-dependent transferase-like [53382]
    main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest
  4. Superfamily: PLP-dependent transferases [53383]
    link to SUPERFAMILY database - Superfamily

Families:

  1. AAT-like [53384] (28)
    1. Aspartate aminotransferase, AAT [53385]
      1. Chicken (Gallus gallus), mitochondria [TaxId: 9031] [53386] (15) picpic
      2. Chicken (Gallus gallus), cytosolic form [TaxId: 9031] [53387] (3) picpic
      3. Pig (Sus scrofa), cytosolic form [TaxId: 9823] [53388] (2) picpic
      4. Baker's yeast (Saccharomyces cerevisiae), cytosolic form [TaxId: 4932] [53389] (1) picpic
      5. Escherichia coli [TaxId: 562] [53390] (65) picpic
        SQ P00509
      6. Thermus thermophilus [TaxId: 274] [53391] (9) picpic
      7. Phormidium lapideum [TaxId: 32060] [82481] (1) picpic
      8. Thermotoga maritima [TaxId: 2336] [89754] (1) picpic
        TM1255
    2. Aromatic aminoacid aminotransferase, AroAT [53392]
      1. Paracoccus denitrificans [TaxId: 266] [53393] (12) picpic
      2. Escherichia coli [TaxId: 562] [53394] (1) picpic
      3. Archaeon Pyrococcus horikoshii [TaxId: 53953] [64120] (3) picpic
    3. Tyrosine aminotransferase (TAT) [53395]
      1. Trypanosoma cruzi [TaxId: 5693] [53396] (1) picpic
    4. Histidinol-phosphate aminotransferase HisC [64121]
      1. Escherichia coli [TaxId: 562] [64122] (6) picpic
      2. Thermotoga maritima [TaxId: 2336] [102594] (8) picpic
        SQ Q9X0D0
        TM1040
    5. L-threonine-O-3-phosphate decarboxylase CobD [69563]
      1. Salmonella enterica [TaxId: 28901] [69564] (4) picpic
    6. Low-specificity threonine aldolase [64123]
      1. Thermotoga maritima [TaxId: 2336] [64124] (8) picpic
      2. Leishmania major [TaxId: 5664] [110676] (1) picpic
        SQ O15839
    7. Alliinase [82482]
      cysteine sulphoxide lyase
      1. Garlic (Allium sativum) [TaxId: 4682] [82483] (6) picpic
    8. Glutamine aminotransferase [110677]
      1. Thermus thermophilus [TaxId: 274] [110678] (3) picpic
        SQ Q75WK2
    9. Putative methionine aminotransferase YdbL [110679]
      1. Escherichia coli [TaxId: 562] [110680] (1) picpic
        SQ P77806
    10. Kynurenine--oxoglutarate transaminase I [110681]
      1. Human (Homo sapiens) [TaxId: 9606] [110682] (3) picpic
        SQ Q16773
      2. Yellowfever mosquito (Aedes aegypti) [TaxId: 7159] [142654] (8) picpic
        SQ Q95VY4 61-477
    11. Putative aminotransferase TM1131 [117691]
      1. Thermotoga maritima [TaxId: 2336] [117692] (1) picpic
        SQ Q9X0L5
    12. Putative alanine aminotransferase [117693]
      1. Pyrococcus furiosus [TaxId: 2261] [117694] (1) picpic
        SQ Q9P9M8
    13. Multiple substrate aminotransferase, MSAT [142655]
      1. Thermococcus profundus [TaxId: 49899] [142656] (1) picpic
        SQ Q9V2W5 13-415
    14. Hypothetical aminotransferase PH0207 [142657]
      1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [142658] (1) picpic
        SQ O57946 26-428
    15. Phenylserine aldolase PSALD [142659]
      most similar to the low-specificity threonine aldolase
      1. Pseudomonas putida [TaxId: 303] [142660] (1) picpic
        SQ Q59IT3 7-351
    16. AAT homologue TM1698 [142661]
      1. Thermotoga maritima [TaxId: 2336] [142662] (6) picpic
        SQ Q9X224 4-392
  2. Beta-eliminating lyases [53397] (4)
    1. Tyrosine phenol-lyase [53398]
      1. Citrobacter intermedius [TaxId: 66695] [53399] (2) picpic
      2. Erwinia herbicola [TaxId: 549] [102595] (1) picpic
    2. Tryptophan indol-lyase (tryptophanase) [53400]
      1. Proteus vulgaris [TaxId: 585] [53401] (1) picpic
      2. Escherichia coli [TaxId: 562] [159703] (7) picpic
        SQ P0A853 5-471! SQ Q8XB34 5-471
  3. Pyridoxal-dependent decarboxylase [69565] (3)
    1. DOPA decarboxylase [69566]
      1. Pig (Sus scrofa) [TaxId: 9823] [69567] (2) picpic
    2. Glutamate decarboxylase beta, GadB [102596]
      1. Escherichia coli [TaxId: 562] [102597] (14) picpic
    3. Glutamate decarboxylase alpha, GadA [117695]
      1. Escherichia coli [TaxId: 562] [117696] (1) picpic
        SQ P69908
  4. Cystathionine synthase-like [53402] (24)
    1. Cystathionine beta-lyase, CBL [53403]
      1. Escherichia coli [TaxId: 562] [53404] (6) picpic
      2. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [64125] (1) picpic
    2. Cystathionine gamma-synthase, CGS [53405]
      1. Escherichia coli [TaxId: 562] [53406] (1) picpic
      2. Common tobacco (Nicotiana tabacum) [TaxId: 4097] [53407] (4) picpic
    3. Cystathionine gamma-lyase (CYS3) [82484]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82485] (1) picpic
    4. Methionine gamma-lyase, MGL [64126]
      1. Trichomonas vaginalis, MGL1 [TaxId: 5722] [64127] (2) picpic
      2. Pseudomonas putida [TaxId: 303] [75271] (8) picpic
        SQ P13254
      3. Trichomonas vaginalis, MGL2 [TaxId: 5722] [110683] (1) picpic
        SQ O15565
      4. Citrobacter freundii [TaxId: 546] [142663] (1) picpic
        SQ Q84AR1 2-398
    5. Modulator in mal gene expression, MalY [53408]
      1. Escherichia coli [TaxId: 562] [53409] (1) picpic
    6. Cystalysin [53410]
      PLP-dependent haemolytic enzyme
      1. Treponema denticola [TaxId: 158] [53411] (2) picpic
    7. NifS-like protein/selenocysteine lyase [53412]
      1. Thermotoga maritima [TaxId: 2336] [53413] (2) picpic
      2. Escherichia coli [TaxId: 562] [53414] (5) picpic
        gene product CsdB
    8. Cysteine desulfurase IscS [89755]
      1. Escherichia coli [TaxId: 562] [89756] (1) picpic
    9. Alanine-glyoxylate aminotransferase [89757]
      1. Human (Homo sapiens) [TaxId: 9606] [89758] (2) picpic
      2. Cyanobacteria (Nostoc sp. pcc 7120) [TaxId: 103690] [102598] (1) picpic
        alr1004
      3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [142664] (1) picpic
        SQ P43567 3-384
    10. Subgroup IV putative aspartate aminotransferase [102599]
      1. Thermus thermophilus [TaxId: 274] [102600] (1) picpic
    11. Kynureninase [102601]
      1. Pseudomonas fluorescens [TaxId: 294] [102602] (1) picpic
    12. 2-aminoethylphosphonate transaminase [82486]
      1. Salmonella typhimurium [TaxId: 90371] [82487] (1) picpic
    13. Cystine C-S lyase C-des [53415]
      1. Synechocystis sp. [TaxId: 1143] [53416] (4) picpic
    14. Probable cysteine desulfurase SufS [110684]
      1. Synechocystis sp. PCC 6803 [TaxId: 1148] [110685] (1) picpic
        SQ Q55793 # slr0077
    15. O-acetyl-L-homoserine sulfhydrylase [142665]
      1. Thermus thermophilus [TaxId: 274] [142666] (2) picpic
        SQ Q93I77 1-421
    16. 3-hydroxykynurenine transaminase [142667]
      1. Malaria mosquito (Anopheles gambiae) [TaxId: 7165] [142668] (8) picpic
        SQ Q4LAM2 2-389
  5. GABA-aminotransferase-like [53417] (27)
    formerly omega-Aminoacid:pyruvate aminotransferase-like
    1. Dialkylglycine decarboxylase [53418]
      1. Pseudomonas cepacia [TaxId: 292] [53419] (16) picpic
    2. Glutamate-1-semialdehyde aminomutase (aminotransferase) [53420]
      1. Synechococcus sp., strain GR6 [TaxId: 1131] [53421] (3) picpic
      2. Synechococcus elongatus [TaxId: 32046] [142669] (1) picpic
        SQ Q8DLK8 45-437
    3. Ornithine aminotransferase [53422]
      1. Human (Homo sapiens) [TaxId: 9606] [53423] (10) picpic
      2. Plasmodium yoelii yoelii [TaxId: 73239] [142670] (6) picpic
        SQ Q7RT90 7-410
    4. 4-aminobutyrate aminotransferase, GABA-aminotransferase [53424]
      1. Pig (Sus scrofa) [TaxId: 9823] [53425] (3) picpic
      2. Escherichia coli [TaxId: 562] [110686] (14) picpic
        SQ P22256
    5. Phosphoserine aminotransferase, PSAT [53426]
      1. Bacillus circulans, subsp. alkalophilus [TaxId: 1397] [53427] (4) picpic
        SQ Q59196
      2. Escherichia coli [TaxId: 562] [53428] (2) picpic
      3. Bacillus alcalophilus [TaxId: 1445] [117697] (19) picpic
        SQ Q9RME2
    6. Serine hydroxymethyltransferase [53429]
      1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [53430] (6) picpic
        SQ P07511
      2. Mouse (Mus musculus) [TaxId: 10090] [53431] (1) picpic
      3. Human (Homo sapiens) [TaxId: 9606] [53432] (1) picpic
      4. Escherichia coli [TaxId: 562] [53433] (2) picpic
      5. Bacillus stearothermophilus [TaxId: 1422] [75272] (7) picpic
      6. Human (Homo sapiens), mitochondrial [TaxId: 9606] [142671] (1) picpic
        SQ P34897 42-504
    7. 3-amino-5-hydroxybenzoic acid synthase (AHBA synthase) [53434]
      1. Amycolatopsis mediterranei [TaxId: 33910] [53435] (2) picpic
    8. Aminotransferase ArnB [82488]
      4-amino-4-deoxy-L-arabinose liposaccharide modifying enzyme
      1. Salmonella typhimurium [TaxId: 90371] [82489] (3) picpic
    9. 2-amino-3-ketobutyrate CoA ligase [64128]
      1. Escherichia coli [TaxId: 562] [64129] (1) picpic
    10. PLP-dependent acyl-CoA synthase (8-amino-7-oxonanoate synthase, AONS) [53436]
      1. Escherichia coli [TaxId: 562] [53437] (4) picpic
    11. Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, BioA [53438]
      synonym: 7,8-diaminopelargonic acid synthase
      1. Escherichia coli [TaxId: 562] [53439] (11) picpic
    12. 1-aminocyclopropane-1-carboxylate synthase (ACC synthase) [53440]
      1. Apple (Malus domestica) [TaxId: 3750] [53441] (4) picpic
      2. Tomato (Lycopersicon esculentum) [TaxId: 4081] [64130] (2) picpic
    13. Aminotransferase homolog WlaK (PglE, Cj1121c) [102603]
      1. Campylobacter jejuni [TaxId: 197] [102604] (3) picpic
    14. Spore coat polysaccharide biosynthesis protein C [142672]
      1. Helicobacter pylori [TaxId: 210] [142673] (6) picpic
        SQ O25130 2-372
    15. Acetylornithine/acetyl-lysine aminotransferase ArgD [142674]
      1. Thermus thermophilus [TaxId: 274] [142675] (6) picpic
        SQ Q93R93 9-395
    16. 5-aminolevulinate synthase [142676]
      1. Rhodobacter capsulatus [TaxId: 1061] [142677] (12) picpic
        SQ P18079 2-397
  6. Ornithine decarboxylase major domain [53444] (1)
    1. Ornithine decarboxylase major domain [53445]
      1. Lactobacillus sp., strain 30a [TaxId: 1591] [53446] (2) picpic
  7. Glycine dehydrogenase subunits (GDC-P) [142678] (2)
    Pfam 02347
    1. Glycine dehydrogenase (decarboxylating) subunit 1 [142679]
      1. Thermus thermophilus [TaxId: 274] [142680] (10) picpic
        SQ Q5SKW8 1-437
    2. Glycine dehydrogenase subunit 2 (P-protein) [142681]
      1. Thermus thermophilus [TaxId: 274] [142682] (10) picpic
        SQ Q5SKW7 2-472
  8. SelA-like [142683] (1)
    Pfam 03841
    1. Hypothetical protein MJ0158 [142684]
      1. Archaeon Methanococcus jannaschii [TaxId: 2190] [142685] (2) picpic
        SQ Q57622 9-374
  9. SepSecS-like [159704] (3)
    Pfam 05889
    1. Selenocysteinyl-tRNA synthase (SepSecS) [159705]
      1. Mouse (Mus musculus) [TaxId: 10090] [159706] (3) picpic
        SQ Q6P6M7 23-467
      2. Archaeoglobus fulgidus [TaxId: 2234] [159707] (4) picpic
        SQ O30207 8-371
      3. Methanococcus maripaludis [TaxId: 39152] [159708] (4) picpic
        SQ Q6LZM9 1-434
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk