Structural Classification of Proteins
Fold: PRTase-like
core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
Lineage:
Root:
scop
Class:
Alpha and beta proteins (a/b)
[51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold:
PRTase-like
[53270]
core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
Superfamilies:
PRTase-like
[53271] (2)
uperfamily
Phosphoribosyltransferases (PRTases)
[53272] (36)
Xanthine-guanine PRTase (XPRTase) [53273]
Escherichia coli
[TaxId: 562]
[53274] (5)
1nul
complexed with mo5, so4
chain a
[34011]
chain b
[34012]
1a95
complexed with bo3, gun, mo2, pcp
chain a
[34013]
chain b
[34014]
chain c
[34015]
chain d
[34016]
1a96
complexed with bo3, mo2, pcp, xan
chain a
[34017]
chain b
[34018]
chain c
[34019]
chain d
[34020]
1a98
mutant
chain a
[34021]
chain b
[34022]
1a97
complexed with 5gp, bo3; mutant
chain a
[34023]
chain b
[34024]
chain c
[34025]
chain d
[34026]
Thermoanaerobacter tengcongensis
[TaxId: 119072]
[142552] (2)
SQ
Q8R7L0
3-180
1yfz
complexed with act, imp, mg; mutant
region a:3-180
[123098]
1yfz
automatically matched to 1YFZ A:3-180
complexed with act, imp, mg; mutant
region b:4-180
[123099]
Hypoxanthine-guanine-xanthine PRTase [53275]
Tritrichomonas foetus
[TaxId: 5724]
[53276] (1)
1hgx
complexed with 5gp, so4
chain a
[34027]
chain b
[34028]
Toxoplasma gondii
[TaxId: 5811]
[53277] (5)
1fsg
complexed with 9dg, mo2, mo3, prp
chain a
[34029]
chain c
[34030]
1qk3
complexed with 5gp
chain a
[34031]
chain b
[34032]
chain c
[34033]
chain d
[34034]
1qk5
complexed with mg, pop, xmp; mutant
chain a
[34035]
chain b
[34036]
1qk4
complexed with imp
chain a
[34037]
chain b
[34038]
chain c
[34039]
chain d
[34040]
1dbr
complexed with mg
chain a
[34041]
chain b
[34042]
chain c
[34043]
chain d
[34044]
Leishmania tarentolae
[TaxId: 5689]
[110658] (1)
SQ
Q9NJI5
1pzm
complexed with 5gp
chain a
[104395]
chain b
[104396]
Glutamine PRPP amidotransferase, C-terminal domain [53278]
Bacillus subtilis
[TaxId: 1423]
[53279] (2)
1gph
complexed with amp, fs4
region 1:235-465
[34045]
region 2:235-465
[34046]
region 3:235-465
[34047]
region 4:235-465
[34048]
1ao0
complexed with 5gp, adp, fs4, mg
region a:235-459
[34049]
region b:235-459
[34050]
region c:235-459
[34051]
region d:235-459
[34052]
Escherichia coli
[TaxId: 562]
[53280] (5)
1ecf
complexed with pin
region a:250-492
[34053]
region b:250-500
[34054]
1ecg
complexed with onl, pin
region a:250-492
[34055]
region b:250-500
[34056]
1ecj
complexed with amp
region a:250-492
[34059]
region b:250-492
[34060]
region c:250-492
[34061]
region d:250-492
[34062]
1ecc
complexed with mn, onl, pcp
region a:250-492
[34057]
region b:250-492
[34058]
1ecb
complexed with 5gp, mg
region a:250-481
[34063]
region b:250-478
[34064]
region c:250-482
[34065]
region d:250-481
[34066]
Guanine PRTase [53281]
Giardia lamblia
[TaxId: 5741]
[53282] (2)
1dqn
complexed with imu, ipa, mg, pop
chain a
[34067]
chain b
[34068]
1dqp
complexed with img, ipa
chain a
[34069]
chain b
[34070]
Hypoxanthine-guanine PRTase (HGPRTase) [53283]
Human (Homo sapiens)
[TaxId: 9606]
[53284] (7)
1z7g
automatically matched to d1bzya_
region a:4-217
[124624]
1z7g
automatically matched to d1bzya_
region b:4-217
[124625]
1z7g
automatically matched to d1bzya_
region c:4-217
[124626]
1z7g
automatically matched to d1bzya_
region d:4-217
[124627]
1bzy
complexed with imu, mg, pop
chain a
[34071]
chain b
[34072]
chain c
[34073]
chain d
[34074]
1hmp
complexed with 5gp
chain a
[34075]
chain b
[34076]
1d6n
chain a
[34077]
chain b
[34078]
Plasmodium falciparum
[TaxId: 5833]
[53285] (1)
1cjb
complexed with irp, mg, pop
chain a
[34079]
chain b
[34080]
chain c
[34081]
chain d
[34082]
Thermoanaerobacter tengcongensis
[TaxId: 119072]
[117671] (1)
SQ
Q8R7L0
1r3u
complexed with act, mg
chain a
[111681]
chain b
[111682]
Hypoxanthine PRTase [53286]
Trypanosoma cruzi
[TaxId: 5693]
[53287] (9)
SQ
Q27796
1tc1
complexed with fmb, mes
chain a
[34083]
chain b
[34084]
1i0l
complexed with 7hp, mo2, mo3, prp; mutant
chain a
[71096]
chain b
[71097]
1tc2
complexed with 7hp, mo2, mo3, mw2, prp
chain a
[34085]
chain b
[34086]
1i13
complexed with 7hp, fmt, mo2, mo3, prp; mutant
chain a
[71098]
chain b
[71099]
1i14
complexed with 7hp, mo2, mo3, prp; mutant
chain a
[71100]
chain b
[71101]
1i0i
complexed with 7hp, mo2, mo3, prp; mutant
chain a
[71094]
chain b
[71095]
1p18
complexed with 7hp, mo2, mo3, prp; mutant
chain a
[104053]
chain b
[104054]
1p17
complexed with imp; mutant
chain a
[104049]
chain b
[104050]
chain c
[104051]
chain d
[104052]
1p19
complexed with imp
chain a
[104055]
chain b
[104056]
chain c
[104057]
chain d
[104058]
Escherichia coli
[TaxId: 562]
[75255] (3)
1g9s
complexed with imp
chain a
[70164]
chain b
[70165]
1g9t
complexed with 5gp
chain a
[70166]
chain b
[70167]
1grv
complexed with mg
chain a
[76321]
chain b
[76322]
Salmonella typhimurium
[TaxId: 90371]
[89728] (1)
1j7j
complexed with mg
chain a
[84131]
chain b
[84132]
Adenine PRTase [53288]
Leishmania donovani
[TaxId: 5661]
[53289] (4)
1qb7
complexed with ade, cit, mg
chain a
[34087]
1qcc
complexed with cit
chain a
[34088]
1qb8
complexed with amp, cit, mg
chain a
[34089]
1qcd
complexed with so4
chain a
[34090]
Leishmania tarentolae
[TaxId: 5689]
[102535] (1)
1mzv
complexed with amp, po4
chain a
[91502]
Giardia lamblia
[TaxId: 5741]
[82455] (2)
1l1q
complexed with 9da, so4
chain a
[77653]
1l1r
ternary complex
complexed with 9da, mg, prp
chain a
[77654]
Baker's yeast (Saccharomyces cerevisiae)
[TaxId: 4932]
[69541] (2)
1g2q
chain a
[65117]
chain b
[65118]
1g2p
complexed with so4
chain a
[65116]
Human (Homo sapiens)
[TaxId: 9606]
[102536] (7)
1zn7
automatically matched to d1orea_
complexed with ade, mg, po4, prp, rp5
region a:3-180
[125374]
1zn7
automatically matched to d1orea_
complexed with ade, mg, po4, prp, rp5
region b:3-180
[125375]
1zn8
automatically matched to d1orea_
complexed with amp, cl
region a:3-180
[125376]
1zn8
automatically matched to d1orea_
complexed with amp, cl
region b:3-180
[125377]
1ore
complexed with amp, cl
chain a
[93452]
1zn9
automatically matched to d1orea_
complexed with amp
region a:3-180
[125378]
1zn9
automatically matched to d1orea_
complexed with amp
region b:3-180
[125379]
Orotate PRTase [53290]
Salmonella typhimurium
[TaxId: 90371]
[53291] (3)
1lh0
complexed with mg, oro, prp
chain a
[73896]
chain b
[73897]
1opr
complexed with mg, oro, prp
chain a
[34091]
1sto
complexed with oh, omp
chain a
[34092]
Escherichia coli
[TaxId: 562]
[53292] (1)
1oro
complexed with so4
chain a
[34093]
chain b
[34094]
Streptococcus pyogenes
[TaxId: 1314]
[142553] (2)
SQ
Q9A076
1-208
2aee
complexed with cl, gol, so4
region a:1-208
[126620]
2aee
automatically matched to 2AEE A:1-208
complexed with cl, gol, so4
region b:1-208
[126621]
Uracil PRTase, Upp [53293]
Bacillus caldolyticus
[TaxId: 1394]
[75256] (1)
1i5e
complexed with u5p
chain a
[71116]
chain b
[71117]
Thermotoga maritima
[TaxId: 2336]
[102538] (1)
TM0721
1o5o
structural genomics
complexed with so4, u5p
chain a
[92509]
chain b
[92510]
chain c
[92511]
chain d
[92512]
Toxoplasma gondii
[TaxId: 5811]
[53295] (6)
1bd3
complexed with po4; mutant
chain a
[34098]
chain b
[34099]
chain c
[34100]
chain d
[34101]
1jlr
complexed with gtp, po4; mutant
chain a
[66859]
chain b
[66860]
chain c
[66861]
chain d
[66862]
1upf
complexed with so4, urf; mutant
chain a
[34102]
chain b
[34103]
chain c
[34104]
chain d
[34105]
1upu
complexed with po4, u5p; mutant
chain a
[34110]
chain b
[34111]
chain c
[34112]
chain d
[34113]
1bd4
complexed with po4, ura; mutant
chain a
[34106]
chain b
[34107]
chain c
[34108]
chain d
[34109]
1jls
complexed with mg, po4, prp, ura; mutant
chain a
[66863]
chain b
[66864]
chain c
[66865]
chain d
[66866]
Thermus thermophilus
[TaxId: 274]
[142554] (4)
SQ
Q72J35
1-208
1v9s
complexed with so4
region a:1-208
[119894]
1v9s
automatically matched to 1V9S A:1-208
complexed with so4
region b:1-208
[119895]
1v9s
automatically matched to 1V9S A:1-208
complexed with so4
region c:1-208
[119896]
1v9s
automatically matched to 1V9S A:1-208
complexed with so4
region d:1-208
[119897]
Sulfolobus solfataricus
[TaxId: 2287]
[142555] (20)
SQ
Q980Q4
2-216
1xtt
complexed with acy, u5p
region a:2-216
[122300]
1xtt
automatically matched to 1XTT A:2-216
complexed with acy, u5p
region b:2-216
[122301]
1xtt
automatically matched to 1XTT A:2-216
complexed with acy, u5p
region c:2-216
[122302]
1xtt
automatically matched to 1XTT A:2-216
complexed with acy, u5p
region d:2-216
[122303]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region a:2-216
[122304]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region b:2-216
[122305]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region c:2-216
[122306]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region d:2-216
[122307]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region e:2-216
[122308]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region f:2-216
[122309]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region g:2-216
[122310]
1xtu
automatically matched to 1XTT A:2-216
complexed with ctp, u5p
region h:2-216
[122311]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region a:2-216
[122312]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region b:2-216
[122313]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region c:2-216
[122314]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region d:2-216
[122315]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region e:2-216
[122316]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region f:2-216
[122317]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region g:2-216
[122318]
1xtv
automatically matched to 1XTT A:2-216
complexed with u5p
region h:2-216
[122319]
Pyrimidine operon regulator PyrR [109612]
bifunctional protein; contains the uracil PRTase and Pyr RNA-binding activities
Bacillus subtilis
[TaxId: 1423]
[53294] (2)
1a3c
complexed with sm, so4
chain a
[34095]
1a4x
complexed with so4
chain a
[34096]
chain b
[34097]
Thermus thermophilus
[TaxId: 274]
[102537] (1)
TT1027
1ufr
structural genomics
complexed with cl
chain a
[99354]
chain b
[99355]
chain c
[99356]
chain d
[99357]
Bacillus caldolyticus
[TaxId: 1394]
[110659] (7)
SQ
P41007
2igb
automatically matched to d1nona_
complexed with edo, u5p
region a:1-179
[147655]
2igb
automatically matched to d1nona_
complexed with edo, u5p
region b:1-179
[147656]
1xzn
automatically matched to d1nona_
complexed with mg, so4
region a:1-179
[122472]
1xzn
automatically matched to d1nona_
complexed with mg, so4
region b:1-179
[122473]
1non
chain a
[103868]
chain b
[103869]
chain c
[103870]
chain d
[103871]
1xz8
automatically matched to d1nona_
complexed with 3gp, 5gp, mg, u5p
region a:1-179
[122469]
1xz8
automatically matched to d1nona_
complexed with 3gp, 5gp, mg, u5p
region b:1-179
[122470]
Mycobacterium tuberculosis
[TaxId: 1773]
[117672] (1)
SQ
P71807
1w30
mutant
chain a
[114118]
chain b
[114119]
Pur operon repressor (PurR), C-terminal domain [102539]
Bacillus subtilis
[TaxId: 1423]
[102540] (2)
1o57
complexed with 1pe, 2pe, epe, p6g, pg4, so4
region a:75-276
[92484]
region b:75-274
[92486]
region c:75-274
[92488]
region d:75-276
[92490]
1p4a
complexed with pcp
region a:75-276
[94091]
region b:75-273
[94093]
region c:75-273
[94095]
region d:75-273
[94097]
Putative phosphoribosyltransferase TT1426 (TTHA1462) [117673]
Thermus thermophilus
[TaxId: 274]
[117674] (1)
SQ
Q5SIB2
1wd5
complexed with mes
chain a
[114524]
Xanthine phosphoribosyltransferase [142556]
Bacillus subtilis
[TaxId: 1423]
[142557] (6)
SQ
P42085
1-191
1y0b
complexed with g4p, na
region a:1-191
[122476]
1y0b
automatically matched to 1Y0B A:1-191
complexed with g4p, na
region b:1-191
[122477]
1y0b
automatically matched to 1Y0B A:1-191
complexed with g4p, na
region c:1-189
[122478]
1y0b
automatically matched to 1Y0B A:1-191
complexed with g4p, na
region d:1-191
[122479]
2fxv
automatically matched to 1Y0B A:1-191
complexed with 5gp, gol
region a:1-190
[134342]
2fxv
automatically matched to 1Y0B A:1-191
complexed with 5gp, gol
region b:1-190
[134343]
Putative phosphoribosyltransferase TTHA1613 [142558]
putative APRTase in UniProt
Thermus thermophilus
[TaxId: 274]
[142559] (5)
SQ
Q5SHW7
2-175
1vch
complexed with acy, ca, cl
region a:2-175
[119980]
1vch
automatically matched to 1VCH A:2-175
complexed with acy, ca, cl
region b:2-175
[119981]
1vch
automatically matched to 1VCH A:2-175
complexed with acy, ca, cl
region c:2-175
[119982]
1vch
automatically matched to 1VCH A:2-175
complexed with acy, ca, cl
region d:2-175
[119983]
1vch
automatically matched to 1VCH A:2-175
complexed with acy, ca, cl
region e:2-175
[119984]
Pprobable purine phosphoribosyltransferase PH0095 [142560]
Pyrococcus horikoshii
[TaxId: 53953]
[142561] (12)
SQ
O57827
1-153
1vdm
region a:1-153
[119994]
1vdm
automatically matched to 1VDM A:1-153
region b:1-153
[119995]
1vdm
automatically matched to 1VDM A:1-153
region c:1-152
[119996]
1vdm
automatically matched to 1VDM A:1-153
region d:1-152
[119997]
1vdm
automatically matched to 1VDM A:1-153
region e:1-153
[119998]
1vdm
automatically matched to 1VDM A:1-153
region f:1-152
[119999]
1vdm
automatically matched to 1VDM A:1-153
region g:1-152
[120000]
1vdm
automatically matched to 1VDM A:1-153
region h:1-153
[120001]
1vdm
automatically matched to 1VDM A:1-153
region i:1-152
[120002]
1vdm
automatically matched to 1VDM A:1-153
region j:1-152
[120003]
1vdm
automatically matched to 1VDM A:1-153
region k:1-152
[120004]
1vdm
automatically matched to 1VDM A:1-153
region l:1-153
[120005]
Phosphoribosylpyrophosphate synthetase-like
[53296] (3)
duplication: consists of two domains of this fold
Phosphoribosylpyrophosphate synthetase [53297]
Bacillus subtilis
[TaxId: 1423]
[53298] (3)
1dku
complexed with abm, ap2
region a:8-166
[34118]
region a:167-315
[34119]
region b:8-166
[34120]
region b:167-315
[34121]
1dkr
complexed with so4
region a:8-166
[34114]
region a:167-316
[34115]
region b:1-166
[34116]
region b:167-315
[34117]
1ibs
complexed with abm, cd, so4
region a:8-166
[66107]
region a:167-315
[66108]
region b:6-166
[66109]
region b:167-315
[66110]
Methanocaldococcus jannaschii
[TaxId: 2190]
[142562] (16)
SQ
Q58761
1-155! SQ
Q58761
156-284
1u9y
region a:1-155
[119655]
1u9y
region a:156-284
[119656]
1u9y
automatically matched to 1U9Y A:1-155
region b:1-155
[119657]
1u9y
automatically matched to 1U9Y A:156-284
region b:156-284
[119658]
1u9y
automatically matched to 1U9Y A:1-155
region c:1-155
[119659]
1u9y
automatically matched to 1U9Y A:156-284
region c:156-284
[119660]
1u9y
automatically matched to 1U9Y A:1-155
region d:1-155
[119661]
1u9y
automatically matched to 1U9Y A:156-284
region d:156-284
[119662]
1u9z
automatically matched to 1U9Y A:1-155
complexed with amp, r5p
region a:1-155
[119663]
1u9z
automatically matched to 1U9Y A:156-284
complexed with amp, r5p
region a:156-284
[119664]
1u9z
automatically matched to 1U9Y A:1-155
complexed with amp, r5p
region b:1-155
[119665]
1u9z
automatically matched to 1U9Y A:156-284
complexed with amp, r5p
region b:156-284
[119666]
1u9z
automatically matched to 1U9Y A:1-155
complexed with amp, r5p
region c:1-155
[119667]
1u9z
automatically matched to 1U9Y A:156-284
complexed with amp, r5p
region c:156-284
[119668]
1u9z
automatically matched to 1U9Y A:1-155
complexed with amp, r5p
region d:1-155
[119669]
1u9z
automatically matched to 1U9Y A:156-284
complexed with amp, r5p
region d:156-284
[119670]
PRPP synthetase-associated protein 1 [142563]
Human (Homo sapiens)
[TaxId: 9606]
[142564] (12)
SQ
Q14558
167-350! SQ
Q14558
7-166
2c4k
complexed with so4, tam
region a:7-166
[129824]
2c4k
complexed with so4, tam
region a:167-350
[129825]
2c4k
automatically matched to 2C4K A:7-166
complexed with so4, tam
region b:7-166
[129826]
2c4k
automatically matched to 2C4K A:167-350
complexed with so4, tam
region b:167-350
[129827]
2c4k
automatically matched to 2C4K A:7-166
complexed with so4, tam
region c:7-166
[129828]
2c4k
automatically matched to 2C4K A:167-350
complexed with so4, tam
region c:167-350
[129829]
2c4k
automatically matched to 2C4K A:7-166
complexed with so4, tam
region d:7-166
[129830]
2c4k
automatically matched to 2C4K A:167-350
complexed with so4, tam
region d:167-350
[129831]
2c4k
automatically matched to 2C4K A:7-166
complexed with so4, tam
region e:7-166
[129832]
2c4k
automatically matched to 2C4K A:167-350
complexed with so4, tam
region e:167-350
[129833]
2c4k
automatically matched to 2C4K A:7-166
complexed with so4, tam
region f:7-166
[129834]
2c4k
automatically matched to 2C4K A:167-350
complexed with so4, tam
region f:167-350
[129835]
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Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
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© 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk