Structural Classification of Proteins
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Family: AstE/AspA-like

Pfam 04952; Succinylglutamate desuccinylase / Aspartoacylase family; contains extra C-terminal domain, new variant of the Barrel-sandwich hybrid fold (scop_cf 51229)

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Phosphorylase/hydrolase-like [53162]
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. Superfamily: Zn-dependent exopeptidases [53187]
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
    link to SUPERFAMILY database - Superfamily
  5. Family: AstE/AspA-like [142526]
    Pfam 04952; Succinylglutamate desuccinylase / Aspartoacylase family; contains extra C-terminal domain, new variant of the Barrel-sandwich hybrid fold (scop_cf 51229)

Protein Domains:

  1. Succinylglutamate desuccinylase AstE [142527]
    1. Vibrio cholerae [TaxId: 666] [142528] (1)
      SQ Q9KSL4 3-342
      1. 2g9d picpic
        1. region a:3-342 [134798] picpiclink
    2. Vibrio parahaemolyticus [TaxId: 670] [142529] (2)
      SQ Q87Q40 4-342
      1. 2bco picpic
        complexed with zn
        1. region a:4-342 [128302] picpiclink
      2. 2bco picpic
        automatically matched to 2BCO A:4-342
        complexed with zn
        1. region b:4-342 [128303] picpiclink
    3. Escherichia coli [TaxId: 562] [142530] (2)
      SQ P76215 1-322
      1. 1yw6 picpic
        complexed with so4
        1. region a:1-322 [124132] picpiclink
      2. 1yw6 picpic
        automatically matched to 1YW6 A:1-322
        complexed with so4
        1. region b:1-322 [124133] picpiclink
    4. Chromobacterium violaceum [TaxId: 536] [142531] (1)
      SQ Q7NU26 2-332
      1. 1yw4 picpic
        complexed with zn
        1. region a:2-332 [124131] picpiclink
  2. Aspartoacylase AspA [159649]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [159650] (1)
      SQ Q6AZ03 4-310
      1. 2gu2 picpic
        complexed with so4, zn
        1. region a:4-310 [147177] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [159651] (1)
      SQ P45381 9-310
      1. 2i3c picpic
        complexed with po4, zn
        1. region a:9-310 [147498] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
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