Structural Classification of Proteins
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Family: FolH catalytic domain-like

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Phosphorylase/hydrolase-like [53162]
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. Superfamily: Zn-dependent exopeptidases [53187]
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
    link to SUPERFAMILY database - Superfamily
  5. Family: FolH catalytic domain-like [53210]

Protein Domains:

  1. Transferrin receptor ectodomain, protease-like domain [53211]
    1. Human (Homo sapiens) [TaxId: 9606] [53212] (4)
      1. 1de4 picpicxrefxrefxrefxrefxref
        1. region c:122-189,c:383-608 [33848] picpiclink
        2. region f:122-189,f:383-608 [33849] picpiclink
        3. region i:122-189,i:383-608 [33850] picpiclink
      2. 1cx8 picpicxrefxref
        complexed with nag, sm
        1. region a:122-189,a:383-608 [33851] picpiclink
        2. region b:122-189,b:383-608 [33852] picpiclink
        3. region c:122-189,c:383-608 [33853] picpiclink
        4. region d:122-189,d:383-608 [33854] picpiclink
        5. region e:122-189,e:383-608 [33855] picpiclink
        6. region f:122-189,f:383-608 [33856] picpiclink
        7. region g:122-189,g:383-608 [33857] picpiclink
        8. region h:122-189,h:383-608 [33858] picpiclink
      3. 2nsu picpicxrefxrefxrefxref
        automatically matched to d1cx8a3
        1. region a:122-189,a:383-608 [138548] picpiclink
      4. 2nsu picpicxrefxrefxrefxref
        automatically matched to d1cx8a3
        1. region b:122-189,b:383-608 [138551] picpiclink
  2. Glutamate carboxypeptidase II FOLH1 [142522]
    Folate hydrolase 1, FolH homologue
    1. Human (Homo sapiens) [TaxId: 9606] [142523] (17)
      SQ Q04609 57-117,351-593
      1. 3bi1 picpicxrefxref
        automatically matched to d1z8la3
        complexed with 3bi, bma, ca, cl, man, nag, zn
        1. region a:57-117,a:351-593 [155297] picpiclink
      2. 3bhx picpicxrefxref
        automatically matched to d1z8la3
        complexed with bhx, bma, ca, cl, man, nag, zn
        1. region a:57-117,a:351-593 [155291] picpiclink
      3. 2or4 picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, man, nag, qus, zn
        1. region a:57-117,a:351-593 [139260] picpiclink
      4. 3bi0 picpicxrefxref
        automatically matched to d1z8la3
        complexed with bix, bma, ca, cl, man, nag, zn
        1. region a:57-117,a:351-593 [155294] picpiclink
      5. 2pvw picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, g88, man, nag, zn
        1. region a:57-117,a:351-593 [139757] picpiclink
      6. 2oot picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, man, nag, zn
        1. region a:57-117,a:351-593 [139178] picpiclink
      7. 2c6c picpicxrefxref
        complexed with 24i, ca, cl, man, nag, zn
        1. region a:57-117,a:351-593 [129991] picpiclink
      8. 2pvv picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with ca, cl, man, nag, ose, zn
        1. region a:57-117,a:351-593 [139754] picpiclink
      9. 2c6g picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, glu, man, nag, zn
        1. region a:57-117,a:351-593 [129994] picpiclink
      10. 2jbj picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, g88, man, nag, zn
        1. region a:57-117,a:351-593 [138252] picpiclink
      11. 2cij picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, man, met, nag, zn
        1. region a:57-117,a:351-593 [130495] picpiclink
      12. 2c6p picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, nag, po4, zn
        1. region a:57-117,a:351-593 [130003] picpiclink
      13. 2jbk picpicxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with bma, ca, cl, man, nag, qus, zn
        1. region a:57-117,a:351-593 [138255] picpiclink
      14. 1z8l picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with nag, ndg, zn
        1. region a:57-117,a:351-593 [124708] picpiclink
      15. 1z8l picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with nag, ndg, zn
        1. region b:57-117,b:351-593 [124711] picpiclink
      16. 1z8l picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with nag, ndg, zn
        1. region c:57-117,c:351-593 [124714] picpiclink
      17. 1z8l picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2C6C A:57-117,A:351-593
        complexed with nag, ndg, zn
        1. region d:57-117,d:351-593 [124717] picpiclink

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
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