Structural Classification of Proteins

Fold: TK C-terminal domain-like

: 3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: TK C-terminal domain-like [52921]
3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

Superfamilies:

TK C-terminal domain-like [52922] (3)
uperfamily
1. Transketolase C-terminal domain-like [52923] (5)
  1. Transketolase (TK), C-domain [52924]
    two N-terminal domains are PP and Pyr modules of thiamin-binding fold
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [52925] (7)
    2. Maize (Zea mays) [TaxId: 4577] [82430] (1)
    3. Escherichia coli [TaxId: 562] [89712] (7)
    4. Leishmania mexicana mexicana [TaxId: 44270] [117610] (1)
      SQ Q8MPM3
  2. Pyruvate dehydrogenase E1 component, C-domain [75239]
    E1A and E1B fused together in a single-chain protein
    1. Escherichia coli [TaxId: 562] [75240] (14)
2. Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (6)
  1. Branched-chain alpha-keto acid dehydrogenase [52927]
    1. Human (Homo sapiens) [TaxId: 9606] [52928] (21)
      SQ P21953 52-392
    2. Thermus thermophilus [TaxId: 274] [102468] (4)
  2. 2-oxoisovalerate dehydrogenase E1b, C-domain [52929]
    1. Pseudomonas putida [TaxId: 303] [52930] (5)
  3. E1-beta subunit of pyruvate dehydrogenase, C-domain [69521]
    1. Archaeon Pyrobaculum aerophilum [TaxId: 13773] [69522] (1)
    2. Human (Homo sapiens) [TaxId: 9606] [89713] (3)
  4. Pyruvate dehydrogenase E1-beta, PdhB, C-terminal domain [117611]
    1. Bacillus stearothermophilus [TaxId: 1422] [117612] (2)
      SQ P21874
3. Pyruvate-ferredoxin oxidoreductase, PFOR, domain II [52931] (1)
  1. Pyruvate-ferredoxin oxidoreductase, PFOR, domain II [52932]
    1. Desulfovibrio africanus [TaxId: 873] [52933] (17)