Fold: PFL-like glycyl radical enzymes

contains: barrel, closed; n=10, S=10; accommodates a hairpin loop inside the barrel

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: PFL-like glycyl radical enzymes [51997]
   contains: barrel, closed; n=10, S=10; accommodates a hairpin loop inside the barrel

Superfamilies:

1. PFL-like glycyl radical enzymes [51998] (5)
   duplication: the N- and C-terminal halves have similar topologies
   uperfamily
   1. PFL-like [51999] (2)
      Pfam 02901; except the C-terminal ~100 residues covered by Pfam 01228
      1. Pyruvate formate-lyase, PFL [52000]
         1. Escherichia coli [TaxId: 562] [52001] (8)
            1. 1h16
               complexed with coa, dtl, mg, na, pg4, pyr
               1. chain a [76462]
            2. 1h17
               complexed with coa, dtl, mg, na, oxm, pg4
               1. chain a [76463]
            3. 1h18
               complexed with dtl, na, pg4, pyr
               1. chain a [76464]
               2. chain b [76465]
            4. 1cm5
               1. chain a [30671]
               2. chain b [30672]
            5. 1mzo
               complexed with pge, pyr
               1. chain a [79708]
               2. chain b [79709]
            6. 3pfl
               complexed with oxm
               1. chain a [30673]
               2. chain b [30674]
            7. 2pfl
               1. chain a [30675]
               2. chain b [30676]
            8. 1qhm
               1. chain a [30677]
               2. chain b [30678]
      2. Glycerol dehydratase DhaB1 [110445]
         1. Clostridium butyricum [TaxId: 1492] [110446] (3)
            SQ Q8GEZ8
            1. 1r9d
               complexed with gol
               1. chain a [104865]
               2. chain b [104866]
            2. 1r9e
               complexed with pgo
               1. chain a [104867]
               2. chain b [104868]
            3. 1r8w
               1. chain a [104853]
               2. chain b [104854]
   2. R1 subunit of ribonucleotide reductase, C-terminal domain [52002] (2)
      1. R1 subunit of ribonucleotide reductase, C-terminal domain [52003]
         1. Escherichia coli [TaxId: 562] [52004] (8)
            1. 1rlr
               1. region a:222-748 [30679]
            2. 1r1r
               mutant
               1. region a:222-737 [30680]
               2. region b:222-737 [30681]
               3. region c:222-737 [30682]
            3. 5r1r
               mutant
               1. region a:222-738 [30683]
               2. region b:222-738 [30684]
               3. region c:222-738 [30685]
            4. 6r1r
               mutant
               1. region a:222-738 [30686]
               2. region b:222-738 [30687]
               3. region c:222-738 [30688]
            5. 7r1r
               mutant
               1. region a:222-738 [30689]
               2. region b:222-738 [30690]
               3. region c:222-738 [30691]
            6. 2r1r
               complexed with ttp
               1. region a:222-737 [30695]
               2. region b:222-737 [30696]
               3. region c:222-737 [30697]
            7. 3r1r
               complexed with atp
               1. region a:222-737 [30692]
               2. region b:222-737 [30693]
               3. region c:222-737 [30694]
            8. 4r1r
               complexed with gdp, ttp; mutant
               1. region a:222-737 [30698]
               2. region b:222-737 [30699]
               3. region c:222-737 [30700]
         2. Salmonella typhimurium [TaxId: 90371] [110447] (6)
            SQ Q08698
            1. 1peq
               complexed with mg, ttp
               1. region a:175-699 [104132]
            2. 1pem
               1. region a:175-699 [104128]
            3. 1peo
               complexed with dcp, mg
               1. region a:175-699 [104130]
            4. 1peu
               complexed with dtp, mg
               1. region a:175-699 [104134]
            5. 2bq1
               automatically matched to d1pema2
               complexed with dgt, fe, mg
               1. region e:175-699 [128954]
            6. 2bq1
               automatically matched to d1pema2
               complexed with dgt, fe, mg
               1. region f:175-699 [128956]
   3. B12-dependent (class II) ribonucleotide reductase [75131] (1)
      1. B12-dependent (class II) ribonucleotide reductase [75132]
         1. Lactobacillus leichmannii [TaxId: 28039] [75133] (1)
            1. 1l1l
               mutant
               1. chain a [73470]
               2. chain b [73471]
               3. chain c [73472]
               4. chain d [73473]
   4. Class III anaerobic ribonucleotide reductase NRDD subunit [52005] (1)
      1. Class III anaerobic ribonucleotide reductase NRDD subunit [52006]
         1. Bacteriophage T4 [TaxId: 10665] [52007] (5)
            1. 1hk8
               complexed with dgt, mn, zn; mutant
               1. chain a [83540]
            2. 1h7b
               complexed with po4; mutant
               1. chain a [70913]
            3. 1h78
               complexed with dcp, mg; mutant
               1. chain a [70910]
            4. 1h7a
               complexed with dtp, fe2, mg; mutant
               1. chain a [70912]
            5. 1h79
               complexed with fe2, mg, ttp; mutant
               1. chain a [70911]
   5. SP0239-like [159444] (1)
      Pfam 05167; DUF771
      1. Uncharacterized protein SP0239 [159445]
         1. Streptococcus pneumoniae [TaxId: 1313] [159446] (2)
            SQ Q97ST4 1-440
            1. 2ha9
               1. region a:1-440 [147251]
            2. 2ha9
               automatically matched to 2HA9 A:1-440
               1. region b:1-440 [147252]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk