Family: Subtilases

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Subtilisin-like [52742]
   3 layers: a/b/a, parallel beta-sheet of 7 strands, order 2314567; left-handed crossover connection between strands 2 & 3
4. Superfamily: Subtilisin-like [52743]
   uperfamily
5. Family: Subtilases [52744]

Protein Domains:

1. Subtilisin [52745]
   1. Bacillus subtilis, carlsberg [TaxId: 1423] [52746] (6)
      1. 1r0r
         complexed with ca
         1. chain e [96735]
      2. 1cse
         complexed with ca
         1. chain e [32481]
      3. 2sec
         complexed with ca
         1. chain e [32482]
      4. 1sel
         complexed with ca, sec; mutant
         1. chain a [32483]
         2. chain b [32484]
      5. 1oyv
         complexed with ca
         1. chain a [87618]
         2. chain b [87619]
      6. 1sbc
         complexed with ca
         1. chain a [32485]
   2. Bacillus subtilis, E [TaxId: 1423] [52747] (1)
      1. 1scj
         propeptide complex
         complexed with ca; mutant
         1. chain a [32486]
   3. Bacillus licheniformis [TaxId: 1402] [52748] (17)
      1. 1yu6
         automatically matched to d1af4__
         complexed with ca
         1. region a:1-275 [124040]
      2. 1yu6
         automatically matched to d1af4__
         complexed with ca
         1. region b:1-275 [124041]
      3. 1bh6
         complexed with 1bh, ca, na
         1. chain a [32487]
      4. 1avt
         complexed with cld, na
         1. chain a [32488]
      5. 1sca
         complexed with ca, na
         1. chain a [32489]
      6. 1vsb
         complexed with clb
         1. chain a [32491]
      7. 1scn
         complexed with ape, boc, ca, na
         1. chain e [32490]
      8. 1c3l
         complexed with ca, fmt, xe
         1. chain a [32492]
      9. 1scd
         complexed with ca
         1. chain a [32493]
      10. 1be8
          complexed with ca, tca
          1. chain a [32494]
      11. 1bfu
          complexed with ca, dio
          1. chain a [32496]
      12. 1be6
          complexed with ca, ccn, tca
          1. chain a [32495]
      13. 1af4
          complexed with ca, dio
          1. chain a [32500]
      14. 1av7
          complexed with na, sbl
          1. chain a [32499]
      15. 3vsb
          complexed with na, sbd
          1. chain a [32498]
      16. 1bfk
          complexed with ca, ccn
          1. chain a [32497]
      17. 1scb
          complexed with ca, ccn
          1. chain a [32501]
   4. Bacillus lentus, savinase (TM) [TaxId: 1467] [52749] (2)
      SQ P29600
      1. 1svn
         complexed with ca
         1. chain a [32502]
      2. 1tk2
         complexed with ca, orn
         1. chain a [107067]
   5. Bacillus lentus [TaxId: 1467] [52750] (11)
      1. 1gci
         complexed with ca, gol, so4
         1. chain a [32503]
      2. 1st3
         complexed with ca
         1. chain a [32504]
      3. 1c9n
         complexed with ca, seb, so4; mutant
         1. chain a [32505]
      4. 1q5p
         complexed with ca, seb, so4; mutant
         1. chain a [95903]
      5. 1c9m
         complexed with ca, seb, so4; mutant
         1. chain a [32506]
      6. 1ndu
         complexed with ca; mutant
         1. chain a [91823]
      7. 1c9j
         complexed with ca, so4; mutant
         1. chain a [32507]
      8. 1ndq
         complexed with ca
         1. chain a [91822]
      9. 1jea
         complexed with ca, so4
         1. chain a [32509]
      10. 3bx1
          automatically matched to d1gcia_
          complexed with ca, cl, na
          1. region a:1-275 [155702]
      11. 3bx1
          automatically matched to d1gcia_
          complexed with ca, cl, na
          1. region b:1-275 [155703]
   6. Bacillus amyloliquefaciens, Novo/BPN' [TaxId: 1390] [52751] (52)
      SQ P00782 108-382
      1. 1to2
         complexed with 15p, ca, cit, na; mutant
         1. chain e [112595]
      2. 1tm5
         complexed with 1pe, ca, cit, na; mutant
         1. chain e [112515]
      3. 1lw6
         complexed with ca, sul; mutant
         1. chain e [74293]
      4. 1v5i
         automatically matched to d1ubna_
         complexed with ca, gol, so4; mutant
         1. region a:1-275 [119853]
      5. 1y34
         automatically matched to d1lw6e_
         complexed with 15p, ca, cit, na; mutant
         1. region e:1-270 [122579]
      6. 1tm7
         complexed with 1pe, ca, cit, na; mutant
         1. chain e [112518]
      7. 1y1k
         automatically matched to d1lw6e_
         complexed with 15p, ca, cit, na; mutant
         1. region e:1-270 [122547]
      8. 1tm3
         complexed with 1pe, ca, cit, na; mutant
         1. chain e [112511]
      9. 1y4a
         automatically matched to d1lw6e_
         complexed with 15p, ca, cit, na; mutant
         1. region e:1-270 [122613]
      10. 1tmg
          complexed with 15p, 1pe, ca, cit, na; mutant
          1. chain e [112521]
      11. 1y3c
          automatically matched to d1lw6e_
          complexed with 15p, ca, cit, na; mutant
          1. region e:1-270 [122591]
      12. 1to1
          complexed with 1pe, ca, cit, na; mutant
          1. chain e [112593]
      13. 1tm1
          complexed with 1pe, ca, cit, na; mutant
          1. chain e [112509]
      14. 1s01
          complexed with ca, cs, ipa; mutant
          1. chain a [32511]
      15. 1tm4
          complexed with 1pe, ca, cit, na; mutant
          1. chain e [112513]
      16. 1sup
          complexed with ca, na, pms
          1. chain a [32510]
      17. 1a2q
          complexed with acn, ca; mutant
          1. chain a [32512]
      18. 1aqn
          complexed with ca, ipa, unx; mutant
          1. chain a [32514]
      19. 1sub
          complexed with acn, ca, cya, k p; mutant
          1. chain a [32513]
      20. 1au9
          complexed with ca, ipa, unx; mutant
          1. chain a [32516]
      21. 1y3b
          automatically matched to d1lw6e_
          complexed with 15p, ca, cit, na; mutant
          1. region e:1-270 [122590]
      22. 1y3d
          automatically matched to d1lw6e_
          complexed with 15p, ca, cit, na; mutant
          1. region e:1-270 [122592]
      23. 1y3f
          automatically matched to d1lw6e_
          complexed with 15p, ca, cit, na; mutant
          1. region e:1-270 [122593]
      24. 1y33
          automatically matched to d1lw6e_
          complexed with 15p, ca, cit, na; mutant
          1. region e:1-270 [122578]
      25. 1ak9
          complexed with ca, ipa, na; mutant
          1. chain a [32517]
      26. 2st1
          complexed with ca, so4
          1. chain a [32515]
      27. 1y48
          automatically matched to d1lw6e_
          complexed with 15p, ca, cit, na; mutant
          1. region e:1-270 [122612]
      28. 1yjb
          complexed with ca, hyd; mutant
          1. chain a [32519]
      29. 1sbh
          complexed with ca, hyd; mutant
          1. chain a [32518]
      30. 1gns
          complexed with acn, cso; mutant
          1. chain a [70289]
      31. 1sue
          complexed with dfp, na; mutant
          1. chain a [32520]
      32. 1suc
          complexed with acn, cya, k p; mutant
          1. chain a [32521]
      33. 1yjc
          complexed with ca, hyd; mutant
          1. chain a [32524]
      34. 1s02
          complexed with ca, so4; mutant
          1. chain a [32525]
      35. 1gnv
          complexed with mis; mutant
          1. chain a [70291]
      36. 1yja
          complexed with ca, hyd; mutant
          1. chain a [32527]
      37. 2sic
          complexed with ca
          1. chain e [32522]
      38. 1sud
          complexed with acn, ca, cya, k p; mutant
          1. chain a [32526]
      39. 3sic
          complexed with ca
          1. chain e [32523]
      40. 1st2
          complexed with ca, o o, so4
          1. chain a [32528]
      41. 2sni
          complexed with ca
          1. chain e [32529]
      42. 1sbi
          complexed with ca, hyd; mutant
          1. chain a [32533]
      43. 1y4d
          automatically matched to d1lw6e_
          complexed with ca, na; mutant
          1. region e:1-270 [122614]
      44. 1sua
          mutant
          1. chain a [32531]
      45. 1dui
          1. chain a [32530]
      46. 1ubn
          complexed with ca
          1. chain a [32535]
      47. 1spb
          CASP1
          complexed with na; mutant
          1. chain s [32532]
      48. 1sbn
          complexed with ca; mutant
          1. chain e [32534]
      49. 5sic
          complexed with ca; mutant
          1. chain e [32536]
      50. 1sib
          complexed with ca; mutant
          1. chain e [32537]
      51. 1sbt
          1. chain a [32538]
      52. 2sbt
          complexed with acn
          1. chain a [32539]
2. Messentericopeptidase [52752]
   1. Bacillus mesentericus [TaxId: 1408] [52753] (1)
      1. 1mee
         complexed with ca
         1. chain a [32540]
3. M-proteinase [52754]
   1. Bacillus sp., strain ksm-k16 [TaxId: 1409] [52755] (2)
      SQ Q99405 112-380
      1. 1wsd
         complexed with ca, so4
         1. chain a [114848]
      2. 1mpt
         complexed with ca
         1. chain a [32541]
4. Serine protease PB92 (subtilisin PB92) [52756]
   1. Bacillus alcalophilus [TaxId: 1445] [52757] (2)
      identical sequence to Bacillus lentus, TaxId: 1467
      1. 1iav
         complexed with ca, seb, sul; mutant
         1. chain a [62125]
      2. 1ah2
         1. chain a [32542]
5. Thermostable serine protease [52758]
   1. Bacillus sp., AK.1 [TaxId: 1409] [52759] (1)
      1. 1dbi
         1. chain a [32543]
6. Sphericase [75224]
   1. Bacillus sphaericus [TaxId: 1421] [75225] (3)
      1. 2ixt
         automatically matched to d1ea7a_
         complexed with ca
         1. region a:1-309 [147828]
      2. 2ixt
         automatically matched to d1ea7a_
         complexed with ca
         1. region b:1-309 [147829]
      3. 1ea7
         complexed with ca, s
         1. chain a [70086]
7. Thermitase [52760]
   1. Thermoactinomyces vulgaris [TaxId: 2026] [52761] (4)
      1. 1thm
         complexed with ca, na, so4
         1. chain a [32544]
      2. 2tec
         complexed with ca, na
         1. chain e [32545]
      3. 3tec
         complexed with ca
         1. chain e [32546]
      4. 1tec
         complexed with ca, na
         1. chain e [32547]
8. Proteinase K [52762]
   1. Fungus (Tritirachium album), strain limber [TaxId: 37998] [52763] (28)
      SQ P06873
      1. 2pwa
         automatically matched to d1ic6a_
         complexed with b2a, ca, no3, so4
         1. region a:1-279 [139762]
      2. 2v8b
         automatically matched to d1ic6a_
         complexed with ca, se4
         1. region a:1-279 [152780]
      3. 1ic6
         complexed with ca, no3; mutant
         1. chain a [62257]
      4. 1p7w
         complexed with ca, no3
         1. chain a [104083]
      5. 1p7v
         complexed with ca, no3
         1. chain a [104082]
      6. 2id8
         automatically matched to d1ic6a_
         complexed with 2db, ca, cl, no3
         1. region a:1-279 [137269]
      7. 3dyb
         automatically matched to d1ic6a_
         complexed with ca, dg0, epe
         1. region a:1-279 [157939]
      8. 2prk
         complexed with ca
         1. chain a [32548]
      9. 2duj
         automatically matched to d1ic6a_
         complexed with ca, no3
         1. region a:1-279 [131751]
      10. 2pkc
          complexed with na
          1. chain a [32549]
      11. 1egq
          complexed with ca, cbm
          1. chain a [32550]
      12. 2hpz
          automatically matched to d1ic6a_
          complexed with ca, no3
          1. region a:1-279 [136655]
      13. 2pwb
          automatically matched to d1ic6a_
          complexed with ca, cou, no3
          1. region a:1-279 [139763]
      14. 2pyz
          automatically matched to d1ic6a_
          complexed with au4, ca, no3
          1. region a:1-279 [149959]
      15. 2pq2
          automatically matched to d1ic6a_
          complexed with ca, no3; mutant
          1. region a:1-279 [139743]
      16. 2dqk
          automatically matched to d1ic6a_
          complexed with ca, no3
          1. region a:1-279 [131638]
      17. 1ht3
          complexed with ca, hg
          1. chain a [61243]
      18. 1oyo
          complexed with 3id, ca
          1. chain a [87613]
      19. 2g4v
          automatically matched to d1ic6a_
          complexed with ca, cl, k
          1. region a:1-279 [134612]
      20. 2hd4
          automatically matched to d1ic6a_
          complexed with acy, ca
          1. region a:1-279 [136340]
      21. 1cnm
          complexed with ca, ccn
          1. chain a [32552]
      22. 1ptk
          complexed with ca, hg
          1. chain a [32551]
      23. 1pj8
          complexed with hg, nh2
          1. chain a [88121]
      24. 1pek
          1. chain e [32553]
      25. 3prk
          complexed with ca, ch2, msu
          1. chain e [32554]
      26. 1bjr
          complexed with ca
          1. chain e [32555]
      27. 1pfg
          complexed with ace, nh2
          1. chain a [88060]
      28. 2dp4
          automatically matched to d1bjre_
          1. region e:1-279 [131607]
9. Kexin, N-terminal domain [89692]
   1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89693] (4)
      1. 2id4
         automatically matched to d1r64a2
         complexed with ace, ca, mla, na, nag; mutant
         1. region a:122-460 [137266]
      2. 2id4
         automatically matched to d1r64a2
         complexed with ace, ca, mla, na, nag; mutant
         1. region b:122-460 [137268]
      3. 1r64
         complexed with ace, bor, btb, ca, k, nag
         1. region a:121-460 [97141]
         2. region b:121-460 [97143]
      4. 1ot5
         complexed with ace, bor, ca, nag
         1. region a:123-460 [87410]
         2. region b:123-460 [87412]
10. Furin, N-terminal domain [89694]
    1. Mouse (Mus musculus) [TaxId: 10090] [89695] (1)
       1. 1p8j
          complexed with arm, ca, dka, fuc, gal, man, nag, so4
          1. region a:109-442 [87947]
          2. region b:109-442 [87949]
          3. region c:109-442 [87951]
          4. region d:109-442 [87953]
          5. region e:109-442 [87955]
          6. region f:108-442 [87957]
          7. region g:109-442 [87959]
          8. region h:110-442 [87961]
11. Alkaline serine protease kp-43, N-terminal domain [110578]
    1. Bacillus sp. KSM-KP43 [TaxId: 109322] [110579] (3)
       SQ Q93UV9 207-640
       1. 1wmd
          complexed with ca, dox, gol, so4
          1. region a:1-318 [109409]
       2. 1wme
          complexed with ca
          1. region a:1-318 [109411]
       3. 1wmf
          complexed with ca, dox, gol, sme
          1. region a:1-318 [109413]
12. Fervidolysin [117569]
    1. Fervidobacterium pennivorans [TaxId: 93466] [117570] (1)
       SQ Q93LQ6
       1. 1r6v
          complexed with ca; mutant
          1. chain a [111710]
13. Alkaline serine protease Apa1 [117571]
    1. Pseudoalteromonas sp. AS-11 [TaxId: 247492] [117572] (1)
       SQ Q65Z69 145-579
       1. 1v6c
          complexed with ca, pms, so4
          1. chain a [113544]
          2. chain b [113545]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk