Superfamily: Subtilisin-like

uperfamily

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Subtilisin-like [52742]
   3 layers: a/b/a, parallel beta-sheet of 7 strands, order 2314567; left-handed crossover connection between strands 2 & 3
4. Superfamily: Subtilisin-like [52743]
   uperfamily

Families:

1. Subtilases [52744] (18)
   1. Subtilisin [52745]
      1. Bacillus subtilis, carlsberg [TaxId: 1423] [52746] (6)
         1. 1r0r
            complexed with ca
            1. chain e [96735]
         2. 1cse
            complexed with ca
            1. chain e [32481]
         3. 2sec
            complexed with ca
            1. chain e [32482]
         4. 1sel
            complexed with ca, sec; mutant
            1. chain a [32483]
            2. chain b [32484]
         5. 1oyv
            complexed with ca
            1. chain a [87618]
            2. chain b [87619]
         6. 1sbc
            complexed with ca
            1. chain a [32485]
      2. Bacillus subtilis, E [TaxId: 1423] [52747] (1)
         1. 1scj
            propeptide complex
            complexed with ca; mutant
            1. chain a [32486]
      3. Bacillus licheniformis [TaxId: 1402] [52748] (17)
         1. 1yu6
            automatically matched to d1af4__
            complexed with ca
            1. region a:1-275 [124040]
         2. 1yu6
            automatically matched to d1af4__
            complexed with ca
            1. region b:1-275 [124041]
         3. 1bh6
            complexed with 1bh, ca, na
            1. chain a [32487]
         4. 1avt
            complexed with cld, na
            1. chain a [32488]
         5. 1sca
            complexed with ca, na
            1. chain a [32489]
         6. 1vsb
            complexed with clb
            1. chain a [32491]
         7. 1scn
            complexed with ape, boc, ca, na
            1. chain e [32490]
         8. 1c3l
            complexed with ca, fmt, xe
            1. chain a [32492]
         9. 1scd
            complexed with ca
            1. chain a [32493]
         10. 1be8
             complexed with ca, tca
             1. chain a [32494]
         11. 1bfu
             complexed with ca, dio
             1. chain a [32496]
         12. 1be6
             complexed with ca, ccn, tca
             1. chain a [32495]
         13. 1af4
             complexed with ca, dio
             1. chain a [32500]
         14. 1av7
             complexed with na, sbl
             1. chain a [32499]
         15. 3vsb
             complexed with na, sbd
             1. chain a [32498]
         16. 1bfk
             complexed with ca, ccn
             1. chain a [32497]
         17. 1scb
             complexed with ca, ccn
             1. chain a [32501]
      4. Bacillus lentus, savinase (TM) [TaxId: 1467] [52749] (2)
         SQ P29600
         1. 1svn
            complexed with ca
            1. chain a [32502]
         2. 1tk2
            complexed with ca, orn
            1. chain a [107067]
      5. Bacillus lentus [TaxId: 1467] [52750] (11)
         1. 1gci
            complexed with ca, gol, so4
            1. chain a [32503]
         2. 1st3
            complexed with ca
            1. chain a [32504]
         3. 1c9n
            complexed with ca, seb, so4; mutant
            1. chain a [32505]
         4. 1q5p
            complexed with ca, seb, so4; mutant
            1. chain a [95903]
         5. 1c9m
            complexed with ca, seb, so4; mutant
            1. chain a [32506]
         6. 1ndu
            complexed with ca; mutant
            1. chain a [91823]
         7. 1c9j
            complexed with ca, so4; mutant
            1. chain a [32507]
         8. 1ndq
            complexed with ca
            1. chain a [91822]
         9. 1jea
            complexed with ca, so4
            1. chain a [32509]
         10. 3bx1
             automatically matched to d1gcia_
             complexed with ca, cl, na
             1. region a:1-275 [155702]
         11. 3bx1
             automatically matched to d1gcia_
             complexed with ca, cl, na
             1. region b:1-275 [155703]
      6. Bacillus amyloliquefaciens, Novo/BPN' [TaxId: 1390] [52751] (52)
         SQ P00782 108-382
         1. 1to2
            complexed with 15p, ca, cit, na; mutant
            1. chain e [112595]
         2. 1tm5
            complexed with 1pe, ca, cit, na; mutant
            1. chain e [112515]
         3. 1lw6
            complexed with ca, sul; mutant
            1. chain e [74293]
         4. 1v5i
            automatically matched to d1ubna_
            complexed with ca, gol, so4; mutant
            1. region a:1-275 [119853]
         5. 1y34
            automatically matched to d1lw6e_
            complexed with 15p, ca, cit, na; mutant
            1. region e:1-270 [122579]
         6. 1tm7
            complexed with 1pe, ca, cit, na; mutant
            1. chain e [112518]
         7. 1y1k
            automatically matched to d1lw6e_
            complexed with 15p, ca, cit, na; mutant
            1. region e:1-270 [122547]
         8. 1tm3
            complexed with 1pe, ca, cit, na; mutant
            1. chain e [112511]
         9. 1y4a
            automatically matched to d1lw6e_
            complexed with 15p, ca, cit, na; mutant
            1. region e:1-270 [122613]
         10. 1tmg
             complexed with 15p, 1pe, ca, cit, na; mutant
             1. chain e [112521]
         11. 1y3c
             automatically matched to d1lw6e_
             complexed with 15p, ca, cit, na; mutant
             1. region e:1-270 [122591]
         12. 1to1
             complexed with 1pe, ca, cit, na; mutant
             1. chain e [112593]
         13. 1tm1
             complexed with 1pe, ca, cit, na; mutant
             1. chain e [112509]
         14. 1s01
             complexed with ca, cs, ipa; mutant
             1. chain a [32511]
         15. 1tm4
             complexed with 1pe, ca, cit, na; mutant
             1. chain e [112513]
         16. 1sup
             complexed with ca, na, pms
             1. chain a [32510]
         17. 1a2q
             complexed with acn, ca; mutant
             1. chain a [32512]
         18. 1aqn
             complexed with ca, ipa, unx; mutant
             1. chain a [32514]
         19. 1sub
             complexed with acn, ca, cya, k p; mutant
             1. chain a [32513]
         20. 1au9
             complexed with ca, ipa, unx; mutant
             1. chain a [32516]
         21. 1y3b
             automatically matched to d1lw6e_
             complexed with 15p, ca, cit, na; mutant
             1. region e:1-270 [122590]
         22. 1y3d
             automatically matched to d1lw6e_
             complexed with 15p, ca, cit, na; mutant
             1. region e:1-270 [122592]
         23. 1y3f
             automatically matched to d1lw6e_
             complexed with 15p, ca, cit, na; mutant
             1. region e:1-270 [122593]
         24. 1y33
             automatically matched to d1lw6e_
             complexed with 15p, ca, cit, na; mutant
             1. region e:1-270 [122578]
         25. 1ak9
             complexed with ca, ipa, na; mutant
             1. chain a [32517]
         26. 2st1
             complexed with ca, so4
             1. chain a [32515]
         27. 1y48
             automatically matched to d1lw6e_
             complexed with 15p, ca, cit, na; mutant
             1. region e:1-270 [122612]
         28. 1yjb
             complexed with ca, hyd; mutant
             1. chain a [32519]
         29. 1sbh
             complexed with ca, hyd; mutant
             1. chain a [32518]
         30. 1gns
             complexed with acn, cso; mutant
             1. chain a [70289]
         31. 1sue
             complexed with dfp, na; mutant
             1. chain a [32520]
         32. 1suc
             complexed with acn, cya, k p; mutant
             1. chain a [32521]
         33. 1yjc
             complexed with ca, hyd; mutant
             1. chain a [32524]
         34. 1s02
             complexed with ca, so4; mutant
             1. chain a [32525]
         35. 1gnv
             complexed with mis; mutant
             1. chain a [70291]
         36. 1yja
             complexed with ca, hyd; mutant
             1. chain a [32527]
         37. 2sic
             complexed with ca
             1. chain e [32522]
         38. 1sud
             complexed with acn, ca, cya, k p; mutant
             1. chain a [32526]
         39. 3sic
             complexed with ca
             1. chain e [32523]
         40. 1st2
             complexed with ca, o o, so4
             1. chain a [32528]
         41. 2sni
             complexed with ca
             1. chain e [32529]
         42. 1sbi
             complexed with ca, hyd; mutant
             1. chain a [32533]
         43. 1y4d
             automatically matched to d1lw6e_
             complexed with ca, na; mutant
             1. region e:1-270 [122614]
         44. 1sua
             mutant
             1. chain a [32531]
         45. 1dui
             1. chain a [32530]
         46. 1ubn
             complexed with ca
             1. chain a [32535]
         47. 1spb
             CASP1
             complexed with na; mutant
             1. chain s [32532]
         48. 1sbn
             complexed with ca; mutant
             1. chain e [32534]
         49. 5sic
             complexed with ca; mutant
             1. chain e [32536]
         50. 1sib
             complexed with ca; mutant
             1. chain e [32537]
         51. 1sbt
             1. chain a [32538]
         52. 2sbt
             complexed with acn
             1. chain a [32539]
   2. Messentericopeptidase [52752]
      1. Bacillus mesentericus [TaxId: 1408] [52753] (1)
         1. 1mee
            complexed with ca
            1. chain a [32540]
   3. M-proteinase [52754]
      1. Bacillus sp., strain ksm-k16 [TaxId: 1409] [52755] (2)
         SQ Q99405 112-380
         1. 1wsd
            complexed with ca, so4
            1. chain a [114848]
         2. 1mpt
            complexed with ca
            1. chain a [32541]
   4. Serine protease PB92 (subtilisin PB92) [52756]
      1. Bacillus alcalophilus [TaxId: 1445] [52757] (2)
         identical sequence to Bacillus lentus, TaxId: 1467
         1. 1iav
            complexed with ca, seb, sul; mutant
            1. chain a [62125]
         2. 1ah2
            1. chain a [32542]
   5. Thermostable serine protease [52758]
      1. Bacillus sp., AK.1 [TaxId: 1409] [52759] (1)
         1. 1dbi
            1. chain a [32543]
   6. Sphericase [75224]
      1. Bacillus sphaericus [TaxId: 1421] [75225] (3)
         1. 2ixt
            automatically matched to d1ea7a_
            complexed with ca
            1. region a:1-309 [147828]
         2. 2ixt
            automatically matched to d1ea7a_
            complexed with ca
            1. region b:1-309 [147829]
         3. 1ea7
            complexed with ca, s
            1. chain a [70086]
   7. Thermitase [52760]
      1. Thermoactinomyces vulgaris [TaxId: 2026] [52761] (4)
         1. 1thm
            complexed with ca, na, so4
            1. chain a [32544]
         2. 2tec
            complexed with ca, na
            1. chain e [32545]
         3. 3tec
            complexed with ca
            1. chain e [32546]
         4. 1tec
            complexed with ca, na
            1. chain e [32547]
   8. Proteinase K [52762]
      1. Fungus (Tritirachium album), strain limber [TaxId: 37998] [52763] (28)
         SQ P06873
         1. 2pwa
            automatically matched to d1ic6a_
            complexed with b2a, ca, no3, so4
            1. region a:1-279 [139762]
         2. 2v8b
            automatically matched to d1ic6a_
            complexed with ca, se4
            1. region a:1-279 [152780]
         3. 1ic6
            complexed with ca, no3; mutant
            1. chain a [62257]
         4. 1p7w
            complexed with ca, no3
            1. chain a [104083]
         5. 1p7v
            complexed with ca, no3
            1. chain a [104082]
         6. 2id8
            automatically matched to d1ic6a_
            complexed with 2db, ca, cl, no3
            1. region a:1-279 [137269]
         7. 3dyb
            automatically matched to d1ic6a_
            complexed with ca, dg0, epe
            1. region a:1-279 [157939]
         8. 2prk
            complexed with ca
            1. chain a [32548]
         9. 2duj
            automatically matched to d1ic6a_
            complexed with ca, no3
            1. region a:1-279 [131751]
         10. 2pkc
             complexed with na
             1. chain a [32549]
         11. 1egq
             complexed with ca, cbm
             1. chain a [32550]
         12. 2hpz
             automatically matched to d1ic6a_
             complexed with ca, no3
             1. region a:1-279 [136655]
         13. 2pwb
             automatically matched to d1ic6a_
             complexed with ca, cou, no3
             1. region a:1-279 [139763]
         14. 2pyz
             automatically matched to d1ic6a_
             complexed with au4, ca, no3
             1. region a:1-279 [149959]
         15. 2pq2
             automatically matched to d1ic6a_
             complexed with ca, no3; mutant
             1. region a:1-279 [139743]
         16. 2dqk
             automatically matched to d1ic6a_
             complexed with ca, no3
             1. region a:1-279 [131638]
         17. 1ht3
             complexed with ca, hg
             1. chain a [61243]
         18. 1oyo
             complexed with 3id, ca
             1. chain a [87613]
         19. 2g4v
             automatically matched to d1ic6a_
             complexed with ca, cl, k
             1. region a:1-279 [134612]
         20. 2hd4
             automatically matched to d1ic6a_
             complexed with acy, ca
             1. region a:1-279 [136340]
         21. 1cnm
             complexed with ca, ccn
             1. chain a [32552]
         22. 1ptk
             complexed with ca, hg
             1. chain a [32551]
         23. 1pj8
             complexed with hg, nh2
             1. chain a [88121]
         24. 1pek
             1. chain e [32553]
         25. 3prk
             complexed with ca, ch2, msu
             1. chain e [32554]
         26. 1bjr
             complexed with ca
             1. chain e [32555]
         27. 1pfg
             complexed with ace, nh2
             1. chain a [88060]
         28. 2dp4
             automatically matched to d1bjre_
             1. region e:1-279 [131607]
   9. Kexin, N-terminal domain [89692]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89693] (4)
         1. 2id4
            automatically matched to d1r64a2
            complexed with ace, ca, mla, na, nag; mutant
            1. region a:122-460 [137266]
         2. 2id4
            automatically matched to d1r64a2
            complexed with ace, ca, mla, na, nag; mutant
            1. region b:122-460 [137268]
         3. 1r64
            complexed with ace, bor, btb, ca, k, nag
            1. region a:121-460 [97141]
            2. region b:121-460 [97143]
         4. 1ot5
            complexed with ace, bor, ca, nag
            1. region a:123-460 [87410]
            2. region b:123-460 [87412]
   10. Furin, N-terminal domain [89694]
       1. Mouse (Mus musculus) [TaxId: 10090] [89695] (1)
          1. 1p8j
             complexed with arm, ca, dka, fuc, gal, man, nag, so4
             1. region a:109-442 [87947]
             2. region b:109-442 [87949]
             3. region c:109-442 [87951]
             4. region d:109-442 [87953]
             5. region e:109-442 [87955]
             6. region f:108-442 [87957]
             7. region g:109-442 [87959]
             8. region h:110-442 [87961]
   11. Alkaline serine protease kp-43, N-terminal domain [110578]
       1. Bacillus sp. KSM-KP43 [TaxId: 109322] [110579] (3)
          SQ Q93UV9 207-640
          1. 1wmd
             complexed with ca, dox, gol, so4
             1. region a:1-318 [109409]
          2. 1wme
             complexed with ca
             1. region a:1-318 [109411]
          3. 1wmf
             complexed with ca, dox, gol, sme
             1. region a:1-318 [109413]
   12. Fervidolysin [117569]
       1. Fervidobacterium pennivorans [TaxId: 93466] [117570] (1)
          SQ Q93LQ6
          1. 1r6v
             complexed with ca; mutant
             1. chain a [111710]
   13. Alkaline serine protease Apa1 [117571]
       1. Pseudoalteromonas sp. AS-11 [TaxId: 247492] [117572] (1)
          SQ Q65Z69 145-579
          1. 1v6c
             complexed with ca, pms, so4
             1. chain a [113544]
             2. chain b [113545]
2. Serine-carboxyl proteinase, SCP [52764] (3)
   elaborated with additional structures
   1. Serine-carboxyl proteinase, SCP [52765]
      1. Pseudomonas sp., sedolisin [TaxId: 306] [52766] (9)
         1. 1ga6
            CASP4
            complexed with act, ca, gol
            1. chain a [32556]
         2. 1kdv
            complexed with ace, ca, gol, pha
            1. chain a [68486]
         3. 1kdy
            complexed with ace, ca, gol, pha
            1. chain a [68487]
         4. 1nlu
            complexed with ca, iva
            1. chain a [91966]
         5. 1ga1
            complexed with ca, cl, gol; mutant
            1. chain a [32557]
         6. 1ga4
            complexed with ca, gol, iva; mutant
            1. chain a [32558]
         7. 1kdz
            complexed with ca, iva
            1. chain a [68488]
         8. 1ke1
            complexed with ca, iva
            1. chain a [68489]
         9. 1ke2
            complexed with ca, csi, pha
            1. chain a [68490]
      2. Bacillus novosp. MN-32, kumamolisin [TaxId: 198803] [75226] (7)
         SQ Q8RR56 ! SQ Q8RR56
         1. 1t1g
            complexed with ca, so4; mutant
            1. chain a [106246]
         2. 1t1e
            complexed with ca
            1. region a:192-546 [106244]
         3. 1t1i
            complexed with ca, so4; mutant
            1. chain a [106248]
         4. 1gt9
            complexed with ca, so4
            1. chain 1 [70438]
            2. chain 2 [70439]
         5. 1gtj
            complexed with ace, ca, so4
            1. chain 1 [70503]
            2. chain 2 [70504]
         6. 1gtg
            complexed with ca
            1. chain 1 [70482]
         7. 1gtl
            complexed with ace, ca, so4
            1. chain 1 [70505]
            2. chain 2 [70506]
      3. Alicyclobacillus sendaiensis, kumamolisin-as [TaxId: 192387] [102411] (3)
         SQ Q8GB88
         1. 1sio
            complexed with ace, ca, so4
            1. chain a [98888]
            2. chain b [98889]
            3. chain c [98890]
         2. 1sn7
            complexed with ca
            1. chain a [105806]
         3. 1siu
            complexed with ca, so4; mutant
            1. chain a [98891]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk