Structural Classification of Proteins
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Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD

Pfam 02441; formerly DFP, DNA/pantothenate metabolism flavoprotein family

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [52506]
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456
  4. Superfamily: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [52507]
    link to SUPERFAMILY database - Superfamily
  5. Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [52508]
    Pfam 02441; formerly DFP, DNA/pantothenate metabolism flavoprotein family

Protein Domains:

  1. 4'-phosphopantothenoylcysteine decarboxylase (PPC decarboxylase, halotolerance protein Hal3a) [52509]
    involved in signal transduction; binds FMN
    1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [52510] (3)
      1. 1mvl picpic
        complexed with fmn; mutant
        1. chain a [85146] picpiclink
      2. 1e20 picpic
        complexed with bme, fmn, ni
        1. chain a [31759] picpiclink
      3. 1mvn picpic
        complexed with fmn, pco; mutant
        1. chain a [85147] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [102300] (1)
      hypothetical protein mds018
      1. 1qzu picpic
        complexed with fmn
        1. chain a [96663] picpiclink
        2. chain b [96664] picpiclink
        3. chain c [96665] picpiclink
        4. chain d [96666] picpiclink
  2. Epidermin modifying enzyme (peptidyl-cysteine decarboxylase) EpiD [63996]
    binds FMN
    1. Staphylococcus epidermidis [TaxId: 1282] [63997] (2)
      1. 1g5q picpic
        complexed with fmn, trs; mutant
        1. chain a [60288] picpiclink
        2. chain d [60289] picpiclink
        3. chain g [60290] picpiclink
        4. chain l [60291] picpiclink
      2. 1g63 picpic
        complexed with fmn
        1. chain a [60299] picpiclink
        2. chain b [60300] picpiclink
        3. chain c [60301] picpiclink
        4. chain d [60302] picpiclink
        5. chain e [60303] picpiclink
        6. chain f [60304] picpiclink
        7. chain g [60305] picpiclink
        8. chain h [60306] picpiclink
        9. chain i [60307] picpiclink
        10. chain j [60308] picpiclink
        11. chain k [60309] picpiclink
        12. chain l [60310] picpiclink
  3. MrsD [102301]
    binds FAD
    1. Bacillus sp. hil-y85/54728 [TaxId: 69002] [102302] (1)
      1. 1p3y picpic
        complexed with fad
        1. chain 1 [94071] picpiclink
  4. Probable aromatic acid decarboxylase Pad1 [117500]
    1. Escherichia coli O157:H7 [TaxId: 83334] [117501] (1)
      SQ Q9X728
      1. 1sbz picpic
        complexed with fmn
        1. chain a [112068] picpiclink
        2. chain b [112069] picpiclink
        3. chain c [112070] picpiclink
        4. chain d [112071] picpiclink

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk