Structural Classification of Proteins
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Family: Quinone reductase

binds FAD

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Flavodoxin-like [52171]
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. Superfamily: Flavoproteins [52218]
    link to SUPERFAMILY database - Superfamily
  5. Family: Quinone reductase [52235]
    binds FAD

Protein Domains:

  1. NAD(P)H:quinone reductase [52236]
    1. Mouse (Mus musculus) [TaxId: 10090] [52237] (1)
      1. 1dxq picpic
        complexed with fad
        1. chain a [31213] picpiclink
        2. chain b [31214] picpiclink
        3. chain c [31215] picpiclink
        4. chain d [31216] picpiclink
    2. Rat (Rattus rattus) [TaxId: 10117] [52238] (1)
      1. 1qrd picpic
        complexed with cbd, dqn, fad
        1. chain a [31217] picpiclink
        2. chain b [31218] picpiclink
    3. Human (Homo sapiens) [TaxId: 9606] [52239] (16)
      1. 1d4a picpic
        complexed with fad
        1. chain a [31219] picpiclink
        2. chain b [31220] picpiclink
        3. chain c [31221] picpiclink
        4. chain d [31222] picpiclink
      2. 1kbq picpic
        complexed with 936, fad
        1. chain a [68391] picpiclink
        2. chain b [68392] picpiclink
        3. chain c [68393] picpiclink
        4. chain d [68394] picpiclink
      3. 1h69 picpic
        complexed with arh, fad
        1. chain a [60665] picpiclink
        2. chain b [60666] picpiclink
        3. chain c [60667] picpiclink
        4. chain d [60668] picpiclink
      4. 1h66 picpic
        complexed with fad, rh1
        1. chain a [60660] picpiclink
        2. chain b [60661] picpiclink
        3. chain c [60662] picpiclink
        4. chain d [60663] picpiclink
      5. 1kbo picpic
        complexed with 340, fad
        1. chain a [68387] picpiclink
        2. chain b [68388] picpiclink
        3. chain c [68389] picpiclink
        4. chain d [68390] picpiclink
      6. 1dxo picpic
        complexed with dqn, fad
        1. chain a [31223] picpiclink
        2. chain b [31224] picpiclink
        3. chain c [31225] picpiclink
        4. chain d [31226] picpiclink
      7. 1gg5 picpic
        complexed with e09, fad
        1. chain a [60480] picpiclink
        2. chain b [60481] picpiclink
        3. chain c [60482] picpiclink
        4. chain d [60483] picpiclink
      8. 1qbg picpic
        complexed with fad
        1. chain a [31227] picpiclink
        2. chain b [31228] picpiclink
        3. chain c [31229] picpiclink
        4. chain d [31230] picpiclink
      9. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region a:1-273 [132783] picpiclink
      10. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region b:1-273 [132784] picpiclink
      11. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region c:1-273 [132785] picpiclink
      12. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region d:1-273 [132786] picpiclink
      13. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region e:1-273 [132787] picpiclink
      14. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region f:1-273 [132788] picpiclink
      15. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region g:1-273 [132789] picpiclink
      16. 2f1o picpic
        automatically matched to d1d4aa_
        complexed with dtc, fad
        1. region h:1-273 [132790] picpiclink
  2. Quinone reductase type 2 (menadione reductase) [52240]
    1. Human (Homo sapiens) [TaxId: 9606] [52241] (24)
      1. 2qwx picpic
        automatically matched to d1qr2a_
        complexed with fad, ml1, zn
        1. region a:1-230 [151441] picpiclink
      2. 2qwx picpic
        automatically matched to d1qr2a_
        complexed with fad, ml1, zn
        1. region b:1-230 [151442] picpiclink
      3. 1sg0 picpic
        automatically matched to d1qr2a_
        complexed with fad, stl, zn
        1. region a:1-230 [118955] picpiclink
      4. 1sg0 picpic
        automatically matched to d1qr2a_
        complexed with fad, stl, zn
        1. region b:1-230 [118956] picpiclink
      5. 1xi2 picpic
        automatically matched to d1qr2a_
        complexed with cb1, fad, zn
        1. region a:1-230 [122012] picpiclink
      6. 1xi2 picpic
        automatically matched to d1qr2a_
        complexed with cb1, fad, zn
        1. region b:1-230 [122013] picpiclink
      7. 2qx4 picpic
        automatically matched to d1qr2a_
        complexed with fad, ml1, zn
        1. region a:1-230 [151447] picpiclink
      8. 2qx4 picpic
        automatically matched to d1qr2a_
        complexed with fad, ml1, zn
        1. region b:1-230 [151448] picpiclink
      9. 2qx8 picpic
        automatically matched to d1qr2a_
        complexed with cl, fad, gol, ml2, zn
        1. region a:1-230 [151451] picpiclink
      10. 2qx8 picpic
        automatically matched to d1qr2a_
        complexed with cl, fad, gol, ml2, zn
        1. region b:1-230 [151452] picpiclink
      11. 2qx6 picpic
        automatically matched to d1qr2a_
        complexed with fad, ml1, zn
        1. region a:1-230 [151449] picpiclink
      12. 2qx6 picpic
        automatically matched to d1qr2a_
        complexed with fad, ml1, zn
        1. region b:1-230 [151450] picpiclink
      13. 2bzs picpic
        automatically matched to d1qr2a_
        complexed with cb1, fad, zn
        1. region a:1-230 [129560] picpiclink
      14. 2bzs picpic
        automatically matched to d1qr2a_
        complexed with cb1, fad, zn
        1. region b:1-230 [129561] picpiclink
      15. 2qmz picpic
        automatically matched to d1qr2a_
        complexed with fad, ldp, zn
        1. region a:1-230 [150905] picpiclink
      16. 2qmz picpic
        automatically matched to d1qr2a_
        complexed with fad, ldp, zn
        1. region b:1-230 [150906] picpiclink
      17. 1zx1 picpic
        automatically matched to d1qr2a_
        complexed with cb1, fad, zn
        1. region a:1-228 [125760] picpiclink
      18. 1zx1 picpic
        automatically matched to d1qr2a_
        complexed with cb1, fad, zn
        1. region b:2-230 [125761] picpiclink
      19. 1qr2 picpic
        complexed with fad, zn
        1. chain a [31231] picpiclink
        2. chain b [31232] picpiclink
      20. 2qr2 picpic
        complexed with fad, vk3, zn
        1. chain a [31233] picpiclink
        2. chain b [31234] picpiclink
      21. 2qx9 picpic
        automatically matched to d1qr2a_
        complexed with fad, ml2, zn
        1. region a:1-230 [151453] picpiclink
      22. 2qx9 picpic
        automatically matched to d1qr2a_
        complexed with fad, ml2, zn
        1. region b:1-230 [151454] picpiclink
      23. 2qmy picpic
        automatically matched to d1qr2a_
        complexed with ad1, fad, zn
        1. region a:1-230 [150903] picpiclink
      24. 2qmy picpic
        automatically matched to d1qr2a_
        complexed with ad1, fad, zn
        1. region b:1-230 [150904] picpiclink
  3. ACP phosphodiesterase AcpD [110470]
    evolved new enzymatic activity
    1. Escherichia coli [TaxId: 562] [110471] (8)
      SQ P41407
      1. 2z98 picpic
        automatically matched to d1tika_
        complexed with edo, fmn
        1. region a:1-200 [154234] picpiclink
      2. 2z9b picpic
        automatically matched to d1tika_
        complexed with edo, fmn
        1. region a:1-200 [154237] picpiclink
      3. 1v4b picpic
        automatically matched to d1tika_
        complexed with edo, fmn, ipa
        1. region a:1-200 [119834] picpiclink
      4. 2z9d picpic
        automatically matched to d1tika_
        complexed with fmn
        1. region a:1-200 [154239] picpiclink
      5. 2z9d picpic
        automatically matched to d1tika_
        complexed with fmn
        1. region b:1-200 [154240] picpiclink
      6. 1tik picpic
        Structural genomics target
        complexed with so4
        1. chain a [107003] picpiclink
      7. 2z9c picpic
        automatically matched to d1tika_
        complexed with dtc, fmn, gol
        1. region a:1-200 [154238] picpiclink
      8. 2d5i picpic
        automatically matched to d1tika_
        complexed with fmn, gol
        1. region a:1-200 [131270] picpiclink
    2. Salmonella typhimurium [TaxId: 90371] [110472] (1)
      SQ Q8XFP4
      1. 1t5b picpic
        Structural genomics target
        complexed with FMN
        complexed with fmn
        1. chain a [106433] picpiclink
        2. chain b [106434] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk