Structural Classification of Proteins
home mail help root up expand collapse

Family: Class I glutamine amidotransferases (GAT)

contains a catalytic Cys-His-Glu triad

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Flavodoxin-like [52171]
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. Superfamily: Class I glutamine amidotransferase-like [52317]
    conserved positions of the oxyanion hole and catalytic nucleophile; different constituent families contain different additional structures
    link to SUPERFAMILY database - Superfamily
  5. Family: Class I glutamine amidotransferases (GAT) [52318]
    contains a catalytic Cys-His-Glu triad

Protein Domains:

  1. GMP synthetase [52319]
    1. Escherichia coli [TaxId: 562] [52320] (1)
      1. 1gpm picpicxrefxref
        complexed with amp, cit, mg, po4, pop
        1. region a:3-207 [31405] picpiclink
        2. region b:3-207 [31406] picpiclink
        3. region c:3-207 [31407] picpiclink
        4. region d:3-207 [31408] picpiclink
  2. Carbamoyl phosphate synthetase, small subunit C-terminal domain [52321]
    1. Escherichia coli [TaxId: 562] [52322] (10)
      SQ P00907
      1. 1a9x picpicxrefxrefxrefxrefxref
        complexed with adp, cl, k, mn, net, orn, po4; mutant
        1. region b:1653-1880 [31409] picpiclink
        2. region d:3653-3880 [31410] picpiclink
        3. region f:5653-5880 [31411] picpiclink
        4. region h:7653-7880 [31412] picpiclink
      2. 1c30 picpicxrefxrefxrefxrefxref
        1. region b:153-380 [31413] picpiclink
        2. region d:153-380 [31414] picpiclink
        3. region f:153-380 [31415] picpiclink
        4. region h:153-380 [31416] picpiclink
      3. 1cs0 picpicxrefxrefxrefxrefxref
        1. region b:153-380 [31417] picpiclink
        2. region d:153-380 [31418] picpiclink
        3. region f:153-380 [31419] picpiclink
        4. region h:153-380 [31420] picpiclink
      4. 1t36 picpicxrefxrefxrefxrefxref
        complexed with adp, cl, k, mn, net, orn, po4, u; mutant
        1. region b:153-380 [106308] picpiclink
        2. region d:153-380 [106316] picpiclink
        3. region f:153-380 [106324] picpiclink
        4. region h:153-380 [106332] picpiclink
      5. 1jdb picpicxrefxrefxrefxrefxref
        complexed with adp, cl, e4n, k, mn, orn, po4
        1. region c:153-380 [31433] picpiclink
        2. region f:153-381 [31434] picpiclink
        3. region i:153-380 [31435] picpiclink
        4. region l:153-380 [31436] picpiclink
      6. 1kee picpicxrefxrefxrefxrefxref
        complexed with 143, adp, cl, k, mn, net, orn, pi
        1. region b:153-380 [68499] picpiclink
        2. region d:153-380 [68507] picpiclink
        3. region f:153-380 [68515] picpiclink
        4. region h:153-380 [68523] picpiclink
      7. 1m6v picpicxrefxrefxrefxrefxref
        complexed with adp, cl, k, mn, net, orn, pi; mutant
        1. region b:153-380 [74543] picpiclink
        2. region d:153-380 [74551] picpiclink
        3. region f:153-380 [74559] picpiclink
        4. region h:153-380 [74567] picpiclink
      8. 1c3o picpicxrefxrefxrefxrefxref
        1. region b:153-380 [31421] picpiclink
        2. region d:153-380 [31422] picpiclink
        3. region f:153-380 [31423] picpiclink
        4. region h:153-380 [31424] picpiclink
      9. 1ce8 picpicxrefxrefxrefxrefxref
        complexed with adp, cl, imp, k, mn, net, orn, pi
        1. region b:153-380 [31425] picpiclink
        2. region d:153-380 [31426] picpiclink
        3. region f:153-380 [31427] picpiclink
        4. region h:153-380 [31428] picpiclink
      10. 1bxr picpicxrefxrefxrefxrefxref
        complexed with anp, cl, k, mn, net, orn
        1. region b:153-380 [31429] picpiclink
        2. region d:153-380 [31430] picpiclink
        3. region f:153-380 [31431] picpiclink
        4. region h:153-380 [31432] picpiclink
  3. Anthranilate synthase GAT subunit, TrpG [52323]
    1. Archaeon Sulfolobus solfataricus [TaxId: 2287] [52324] (1)
      1. 1qdl picpicxref
        1. chain b [31437] picpiclink
    2. Salmonella typhimurium [TaxId: 90371] [63969] (1)
      1. 1i1q picpicxref
        complexed with trp
        1. chain b [61544] picpiclink
    3. Serratia marcescens [TaxId: 615] [63970] (2)
      1. 1i7q picpicxref
        complexed with bez, ilg, mg, pyr
        1. chain b [61902] picpiclink
        2. chain d [61904] picpiclink
      2. 1i7s picpicxref
        complexed with trp
        1. chain b [61906] picpiclink
        2. chain d [61908] picpiclink
  4. GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF [69447]
    1. Thermotoga maritima [TaxId: 2336] [69448] (3)
      1. 1k9v picpic
        complexed with acy
        1. chain f [68365] picpiclink
      2. 1gpw picpicxref
        complexed with po4; mutant
        1. chain b [65461] picpiclink
        2. chain d [65463] picpiclink
        3. chain f [65465] picpiclink
      3. 1kxj picpic
        complexed with po4
        1. chain a [73153] picpiclink
        2. chain b [73154] picpiclink
    2. Thermus thermophilus [TaxId: 274] [82350] (1)
      1. 1ka9 picpicxref
        1. chain h [77308] picpiclink
    3. Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId: 4932] [69449] (4)
      1. 1jvn picpicxref
        complexed with 143, ni, pop, so4
        1. region a:-3-229 [67356] picpiclink
        2. region b:-3-229 [67358] picpiclink
      2. 1ox6 picpicxref
        complexed with ni, pop, so4
        1. region a:-3-229 [87506] picpiclink
        2. region b:-3-229 [87508] picpiclink
      3. 1ox5 picpicxref
        complexed with 1pr, 5cs, ni; mutant
        1. region a:-3-229 [87502] picpiclink
        2. region b:3-229 [87504] picpiclink
      4. 1ox4 picpicxref
        complexed with cyd, ni, pop, so4
        1. region a:-3-229 [87498] picpiclink
        2. region b:-3-229 [87500] picpiclink
  5. gamma-glutamyl hydrolase [75154]
    1. Human (Homo sapiens) [TaxId: 9606] [75155] (1)
      1. 1l9x picpic
        complexed with bme
        1. chain a [73762] picpiclink
        2. chain b [73763] picpiclink
        3. chain c [73764] picpiclink
        4. chain d [73765] picpiclink
  6. Hypothetical protein TM1158 [89599]
    1. Thermotoga maritima [TaxId: 2336] [89600] (1)
      1. 1o1y picpic
        structural genomics
        complexed with mse, ocs, so4
        1. chain a [86554] picpiclink
  7. Hypothetical protein YaaE [102250]
    glutamine amidotransferase of SNO/PDX2 family implicated in pyridoxine biosynthesis
    1. Bacillus subtilis [TaxId: 1423] [102251] (3)
      1. 2nv0 picpic
        automatically matched to d1r9ga_
        1. region a:1-195 [138625] picpiclink
      2. 2nv0 picpic
        automatically matched to d1r9ga_
        1. region b:1-194 [138626] picpiclink
      3. 1r9g picpic
        1. chain a [97258] picpiclink
        2. chain b [97259] picpiclink
    2. Bacillus stearothermophilus [TaxId: 1422] [102252] (1)
      1. 1q7r picpic
        structural genomics
        complexed with cl, edo, so4
        1. chain a [96054] picpiclink
  8. CTP synthase PyrG, C-terminal domain [110481]
    1. Escherichia coli [TaxId: 562] [110482] (1)
      SQ P08398
      1. 1s1m picpicxref
        complexed with iod, mg, mpd, so4
        1. region a:287-544 [105201] picpiclink
        2. region b:287-545 [105203] picpiclink
    2. Thermus thermophilus [TaxId: 274] [110483] (3)
      SQ Q5SIA8
      1. 1vco picpicxref
        complexed with gln
        1. region a:298-547 [108508] picpiclink
      2. 1vcm picpicxref
        1. region a:298-547 [108504] picpiclink
      3. 1vcn picpicxref
        complexed with so4
        1. region a:298-547 [108506] picpiclink
  9. FGAM synthase PurL, amidotransferase domain [110484]
    1. Salmonella typhimurium [TaxId: 90371] [110485] (1)
      SQ P74881
      1. 1t3t picpicxrefxrefxrefxref
        complexed with adp, mg, so4
        1. region a:1034-1295 [106382] picpiclink
  10. GMP synthase subunit A, GuaAA [142065]
    1. Archaeon Thermoplasma acidophilum [TaxId: 2303] [142066] (4)
      SQ Q9HJM3 1-196
      1. 2a9v picpic
        complexed with cl, gol, scn
        1. region a:1-196 [126452] picpiclink
      2. 2a9v picpic
        automatically matched to 2A9V A:1-196
        complexed with cl, gol, scn
        1. region b:1-196 [126453] picpiclink
      3. 2a9v picpic
        automatically matched to 2A9V A:1-196
        complexed with cl, gol, scn
        1. region c:1-196 [126454] picpiclink
      4. 2a9v picpic
        automatically matched to 2A9V A:1-196
        complexed with cl, gol, scn
        1. region d:1-196 [126455] picpiclink
    2. Archaeon Pyrococcus horikoshii [TaxId: 53953] [142067] (1)
      SQ O59071 1-188
      1. 1wl8 picpic
        complexed with acy, cl, snn
        1. region a:1-188 [120997] picpiclink
  11. Pyridoxine biosynthesis protein 2, Pdx2 [142068]
    1. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [142069] (2)
      SQ Q5ND68 2-219
      1. 2abw picpic
        complexed with pg4
        1. region a:2-219 [126535] picpiclink
      2. 2abw picpic
        automatically matched to 2ABW A:2-219
        complexed with pg4
        1. region b:2-219 [126536] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk